scholarly journals No association of the −521 C/T polymorphism in the promoter of DRD4 with novelty seeking

2001 ◽  
Vol 6 (6) ◽  
pp. 618-619 ◽  
Author(s):  
J Ekelund ◽  
J Suhonen ◽  
M-R Järvelin ◽  
L Peltonen ◽  
D Lichtermann
Keyword(s):  
2010 ◽  
Vol 29 (01/02) ◽  
pp. 31-34 ◽  
Author(s):  
B. Alm ◽  
E. Sobanski
Keyword(s):  

ZusammenfassungDer Zusammenhang zwischen der ADHS des Erwachsenenalters mit Persönlichkeitsstörungen und Persönlichkeitsstruktur wurde noch wenig untersucht. Verfügbare Untersuchungsergebnisse belegen einen Zusammenhang mit spezifischen Persönlichkeitsdimensionen, in erster Linie affektiver Labilität, geringer Selbstverfügbarkeit, passiv-vermeidendem Verhalten bzw. “Novelty seeking” sowie von Cluster-Bund -C-Persönlichkeitsstörungen und der ADHS des Erwachsenenalters, wobei eine differenzielle Assoziation mit Aufmerksamkeitsstörungen und hyperaktiv-impulsivem Verhalten bzw. den Subtypen der ADHS besteht.


Genes ◽  
2021 ◽  
Vol 12 (8) ◽  
pp. 1217
Author(s):  
Marta Niewczas ◽  
Anna Grzywacz ◽  
Katarzyna Leźnicka ◽  
Krzysztof Chmielowiec ◽  
Jolanta Chmielowiec ◽  
...  

Four factors—namely, harm avoidance, novelty seeking, reward addiction and persistence—represent the nature of temperament that is not genetically determined in itself. It was shown in earlier studies that a strong propensity to look for novelty or a tendency to engage in risky behavior is correlated with genetic variants in the area of the genes encoding dopamine receptors. Therefore, the aim of this study is to determine whether there is a relationship between personality traits and genetic variants in the area of the DRD2 dopamine receptor gene in MMA athletes. The participants consisted of 85 mixed martial arts (MMA) athletes and 284 healthy, non-MMA male participants. Their personality traits were measured using the Revised Temperament and Character Inventory. Blood was collected for genetic assays and all samples were genotyped using the real-time PCR method. We observed a statistically significant effect of a complex factor of the DRD2 rs1799732 genotype on MMA participants’ control and reward dependence. Engaging in high-risk sport may be associated with several personality characteristics. The DRD2 rs1799732 polymorphism may be associated with reduced harm avoidance in martial arts athletes, thereby modulating athletes’ predisposition to participate in high-risk sport.


2004 ◽  
Vol 19 (4) ◽  
pp. 193-195 ◽  
Author(s):  
Ladislav Hosák ◽  
Marek Preiss ◽  
Martin Halíř ◽  
Eva Čermáková ◽  
Ladislav Csémy

AbstractWe applied the temperament and character inventory (TCI) personality questionnaire in 41 inpatients dependent on metamphetamine, and 35 controls. Novelty seeking, harm avoidance and self-transcendence were significantly higher, and persistence, self-directedness and cooperativeness were significantly lower in the patients than in the healthy volunteers. The detected differences may be important for prevention and treatment.


2011 ◽  
Vol 71 ◽  
pp. e398
Author(s):  
Ting Li ◽  
Shunying Yu ◽  
Jiang Du ◽  
Hanhui Chen ◽  
Haifeng Jiang ◽  
...  
Keyword(s):  
Drug Use ◽  

2011 ◽  
Vol 186 (1) ◽  
pp. 141-143 ◽  
Author(s):  
Branka Aukst Margetić ◽  
Miro Jakovljević ◽  
Dragutin Ivanec ◽  
Goran Tošić ◽  
Branimir Margetić

2004 ◽  
Vol 34 (8) ◽  
pp. 1407-1418 ◽  
Author(s):  
KELLY L. KLUMP ◽  
MICHAEL STROBER ◽  
CYNTHIA M. BULIK ◽  
LAURA THORNTON ◽  
CRAIG JOHNSON ◽  
...  

Background. Previous studies of personality characteristics in women with eating disorders primarily have focused on women who are acutely ill. This study compares personality characteristics among women who are ill with eating disorders, recovered from eating disorders, and those without eating or other Axis I disorder pathology.Method. Female participants were assessed for personality characteristics using the Temperament and Character Inventory (TCI): 122 with anorexia nervosa (AN; 77 ill, 45 recovered), 279 with bulimia nervosa (BN; 194 ill, 85 recovered), 267 with lifetime histories of both anorexia and bulimia nervosa (AN+BN; 194 ill, 73 recovered), 63 with eating disorder not otherwise specified (EDNOS; 31 ill, 32 recovered), and 507 without eating or Axis I disorder pathology.Results. Women ill with all types of eating disorders exhibited several TCI score differences from control women, particularly in the areas of novelty-seeking, harm avoidance, self-directedness, and cooperativeness. Interestingly, women recovered from eating disorders reported higher levels of harm avoidance and lower self-directedness and cooperativeness scores than did normal control women.Conclusions. Women with eating disorders in both the ill and recovered state show higher levels of harm avoidance and lower self-directedness and cooperativeness scores than normal control women. Although findings suggest that disturbances may be trait-related and contribute to the disorders' pathogenesis, additional research with more representative community controls, rather than our pre-screened, normal controls, is needed to confirm these impressions.


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