Bile acid binding capacity of fish protein hydrolysates from discard species of the West Mediterranean Sea

The valorization of wastes generated in the processing of farmed fish is currently an issue of extreme relevance for the industry, aiming to accomplish the objectives of circular bioeconomy. In the present report, turbot (Scophthalmus maximus) by-products were subjected to Alcalase hydrolysis under the optimal conditions initially defined by response surface methodology. All the fish protein hydrolysates (FPHs) showed a high yield of digestion (>83%), very remarkable degrees of hydrolysis (30–37%), high content of soluble protein (>62 g/L), an excellent profile of amino acids, and almost total in vitro digestibility (higher than 92%). Antioxidant and antihypertensive activities were analyzed in all cases, viscera hydrolysates being the most active. The range of average molecular weights (Mw) of turbot hydrolysates varied from 1200 to 1669 Da, and peptide size distribution showed that the hydrolysate of viscera had the highest content of peptides above 1000 Da and below 200 Da.

Download Full-text

Comparison of in vitro Bile Acid Binding Capacity and in vivo Hypocholesteremic Activity of Cholestyramine

Experimental Biology and Medicine ◽

10.3181/00379727-121-30723 ◽

1966 ◽

Vol 121 (1) ◽

pp. 153-156 ◽

Cited By ~ 9

Author(s):

C. H. Whiteside ◽

H. B. Fluckiger ◽

H. P. Sarett

Keyword(s):

Bile Acid ◽

Binding Capacity ◽

Bile Acid Binding

Download Full-text

In Vitro Bile Acid Binding Capacity of Wheat Bran with Different Particle Sizes

Cereal Chemistry ◽

10.1094/cchem-08-16-0211-r ◽

2017 ◽

Vol 94 (4) ◽

pp. 654-658 ◽

Cited By ~ 3

Author(s):

Chun-yan Li ◽

Andrew L. Mense ◽

Lauren R. Brewer ◽

Chuan Lau ◽

Yong-Cheng Shi

Keyword(s):

Bile Acid ◽

Wheat Bran ◽

Binding Capacity ◽

Particle Sizes ◽

Bile Acid Binding

Download Full-text

Dietary fibre and sterol metabolism in the rat

British Journal Of Nutrition ◽

10.1079/bjn19740096 ◽

1974 ◽

Vol 32 (2) ◽

pp. 447-455 ◽

Cited By ~ 27

Author(s):

B. Morgan ◽

Monique Heald ◽

Sandra D. Atkin ◽

J. Green ◽

E. B. Chain

Keyword(s):

Bile Acid ◽

Dietary Fibre ◽

Synthetic Fibre ◽

Binding Capacity ◽

Sterol Metabolism ◽

Cholesterol Levels ◽

Lignin Fraction ◽

Bile Acid Binding ◽

Hepatic Synthesis

1. Sterol metabolism was studied in rats fed on a semi-synthetic fibre-free diet and in rats fed on diets containing cellulose (200 or 100 g/kg) or sugar-cane fibre (bagasse) at the same levels.2. Rats fed on the diets containing cellulose or bagasse produced significantly greater quantities of faeces than did rats fed on the fibre-free diet.3. Rats given bagasse excreted more bile acid and more neutral sterol in their faeces than did rats fed on cellulose or on the fibre-free diet.4. After 28 d, hepatic synthesis of cholesterol (from acetate) and cholesterol 7α-hydroxylase activity were significantly higher in animals fed on bagasse than in animals fed on the other two diets.5. No significant differences in serum cholesterol levels were seen in rats fed on any of the three diets.6. Food consumption was not substantially altered by the inclusion of bagasse or cellulose in the diets, although the efficiency of foodstuff utilization was generally lower.7. Bagasse adsorbed substantial quantities of cholic acid in vitro, whereas cellulose did not. The lignin fraction prepared from bagasse contributed only slightly to the total bile acid-binding capacity of bagasse.8. The results are discussed in the light of possible effects of dietary fibre on sterol metabolism in man.

Download Full-text