Magnetic core–shell nanoprobe for sensitive killing of cancer cells via induction with a strong external magnetic field

RSC Advances ◽  
2014 ◽  
Vol 4 (39) ◽  
pp. 20077-20085 ◽  
Author(s):  
Samir Mandal ◽  
Nabanita Chatterjee ◽  
Subhadip Das ◽  
Krishna Das Saha ◽  
Keya Chaudhuri

The title system, composed of a highly magnetic core surrounded by a thin arsenite shell, has been synthesized and applied to the magnetically facilitated targeting of anticancer agent (sodium arsenite) at lower dose with minimal side effects and higher efficacy in a biocompatible manner.

2014 ◽  
Vol 2 (12) ◽  
pp. 1750-1760 ◽  
Author(s):  
Tina Gulin-Sarfraz ◽  
Jixi Zhang ◽  
Diti Desai ◽  
Jarmo Teuho ◽  
Jawad Sarfraz ◽  
...  

The joint effect of surface functionalization and an external magnetic field on cellular labeling was studied.


RSC Advances ◽  
2020 ◽  
Vol 10 (64) ◽  
pp. 38818-38830
Author(s):  
Tammar Hussein Ali ◽  
Amar Mousa Mandal ◽  
Thorsten Heidelberg ◽  
Rusnah Syahila Duali Hussen ◽  
Ean Wai Goh

The fabrication ionic magnetic core-shell nanoparticles were simple synthesize with a super-ferromagnetic and small particle size properties, which enabled sufficient DNA particle loading with easy isolation based on an external magnetic field.


2021 ◽  
Author(s):  
Mohd Imran ◽  
Nasser Zouli ◽  
Tansir Ahamad ◽  
Saad M. Alshehri ◽  
Mohammed Rehaan Chandan ◽  
...  

Ferrofluids prepared by dispersing superparamagnetic Fe3O4@C core–shell nanoparticles in water exhibited exceptional enhancement in thermal conductivity without an external magnetic field.


2020 ◽  
Vol 62 (11) ◽  
pp. 2167-2172
Author(s):  
A. S. Kamzin ◽  
I. M. Obaidat ◽  
A. A. Valliulin ◽  
V. G. Semenov ◽  
I. A. Al-Omari

2020 ◽  
Vol 62 (11) ◽  
pp. 1919
Author(s):  
А.С. Камзин ◽  
I.M. Obaidat ◽  
А.А. Валлиулин ◽  
В.Г. Семенов ◽  
I.A. Al-Omari

The results of Mössbauer studies of the composition and magnetic structure of Fe3O4 / -Fe2O3 nanoparticles placed in an external magnetic field with a strength of 1.8 kOe, which is a continuation of the work [A.S. Kamzin, I.M. Obaidat, A.A. Valliulin, V.G. Semenov, I.A. Al-Omari. FTT No. 10/2020]. It is shown that the thickness of the maghemite (-Fe2O3) shell can be changed by the synthesis conditions. It was found that on the surface of the maghemite (-Fe2O3) shell in the Fe3O4 / -Fe2O3 nanocomposites there is a layer in which the magnetic moments are not oriented collinearly to the moments located in the depth of the shell, i.e., there is a canted spin structure. An intermediate layer in the spin-glass state is formed between the core and the shell. The data obtained on the structure of core / shell particles are important for understanding the properties of nanocomposites, which are of great interest for applications in various fields, including biomedicine.


Nanomaterials ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 991 ◽  
Author(s):  
Mohamed S. A. Darwish ◽  
Hohyeon Kim ◽  
Hwangjae Lee ◽  
Chiseon Ryu ◽  
Jae Young Lee ◽  
...  

Magnetic ferrite nanoparticles (MFNs) with high heating efficiency are highly desirable for hyperthermia applications. As conventional MFNs usually show low heating efficiency with a lower specific loss power (SLP), extensive efforts to enhance the SLP of MFNs have been made by varying the particle compositions, sizes, and structures. In this study, we attempted to increase the SLP values by creating core-shell structures of MFNs. Accordingly, first we synthesized three different types of core ferrite nanoparticle of magnetite (mag), cobalt ferrite (cf) and zinc cobalt ferrite (zcf). Secondly, we synthesized eight bi-magnetic core-shell structured MFNs; Fe3O4@CoFe2O4 (mag@cf1, mag@cf2), CoFe2O4@Fe3O4 (cf@mag1, cf@mag2), Fe3O4@ZnCoFe2O4 (mag@zcf1, mag@zcf2), and ZnCoFe2O4@Fe3O4 (zcf@mag1, zcf@mag2), using a modified controlled co-precipitation process. SLP values of the prepared core-shell MFNs were investigated with respect to their compositions and core/shell dimensions while varying the applied magnetic field strength. Hyperthermia properties of the prepared core-shell MFNs were further compared to commercial magnetic nanoparticles under the safe limits of magnetic field parameters (<5 × 109 A/(m·s)). As a result, the highest SLP value (379.2 W/gmetal) was obtained for mag@zcf1, with a magnetic field strength of 50 kA/m and frequency of 97 kHz. On the other hand, the lowest SLP value (1.7 W/gmetal) was obtained for cf@mag1, with a magnetic field strength of 40 kA/m and frequency of 97 kHz. We also found that magnetic properties and thickness of the shell play critical roles in heating efficiency and hyperthermia performance. In conclusion, we successfully enhanced the SLP of MFNs by engineering their compositions and dimensions.


2018 ◽  
Vol 386 ◽  
pp. 156-160
Author(s):  
Ksenya Sergeevna Lukуanenko ◽  
Vladimir Iosifovich Apanasevich ◽  
Leonid Lazarevich Afremov ◽  
Olga Vycheslavovna Tarakova ◽  
Olga Sergeevna Plotnikova ◽  
...  

The possibility of application of magnetic core-shell Fe3O4/Ta2O5nanoparticles has been investigated in order to enhance the effect of radiation therapy. It has been shown, that an increase of the concentration of the core-shell nanoparticles due to the influence of the nonuniform magnetic field enhances the absorption of gamma quanta with energy destroying tumor cells (20-200 keV). In addition, an increase of nanoparticles concentration promotes the formation of electron-positron pairs, annihilation of which are leads to an increase in the number of secondary gamma quanta with an energy of 511 keV.


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