FTIR microspectroscopy coupled with variable selection methods for the identification of flunitrazepam in necrophagous flies

2016 ◽  
Vol 8 (5) ◽  
pp. 968-972 ◽  
Author(s):  
Tainá C. Baia ◽  
Renata A. Gama ◽  
Leomir Aires Silva de Lima ◽  
Kássio M. G. Lima
Keyword(s):  
Variable Selection ◽  
Low Cost ◽  
The Body ◽  
Spectroscopic Techniques ◽  
Selection Methods ◽  
Ftir Microspectroscopy ◽  
Detection And Identification ◽  
Fly Larvae

The detection and identification of a drug in a corpse through the analysis of fly larvae feeding on the body by spectroscopic techniques promises to be of great value, because of their sensitivity, promptness, low cost and simplicity.

Influence of Ascorbic Acid on the Structure and Function of Alpha-2- macroglobulin: Investigations using Spectroscopic and Thermodynamic Techniques

2020 ◽  
Vol 27 (3) ◽  
pp. 201-209
Author(s):  
Syed Saqib Ali ◽  
Mohammad Khalid Zia ◽  
Tooba Siddiqui ◽  
Haseeb Ahsan ◽  
Fahim Halim Khan
Keyword(s):  
Ascorbic Acid ◽  
Conformational Changes ◽  
Structural Changes ◽  
The Body ◽  
Titration Calorimetry ◽  
Spectroscopic Techniques ◽  
Human Beings ◽  
Plasma Ascorbic Acid ◽  
Dietary Antioxidant ◽  
And Function

Background: Ascorbic acid is a classic dietary antioxidant which plays an important role in the body of human beings. It is commonly found in various foods as well as taken as dietary supplement. Objective: The plasma ascorbic acid concentration may range from low, as in chronic or acute oxidative stress to high if delivered intravenously during cancer treatment. Sheep alpha-2- macroglobulin (α2M), a human α2M homologue is a large tetrameric glycoprotein of 630 kDa with antiproteinase activity, found in sheep’s blood. Methods: In the present study, the interaction of ascorbic acid with alpha-2-macroglobulin was explored in the presence of visible light by utilizing various spectroscopic techniques and isothermal titration calorimetry (ITC). Results: UV-vis and fluorescence spectroscopy suggests the formation of a complex between ascorbic acid and α2M apparent by increased absorbance and decreased fluorescence. Secondary structural changes in the α2M were investigated by CD and FT-IR spectroscopy. Our findings suggest the induction of subtle conformational changes in α2M induced by ascorbic acid. Thermodynamics signatures of ascorbic acid and α2M interaction indicate that the binding is an enthalpy-driven process. Conclusion: It is possible that ascorbic acid binds and compromises antiproteinase activity of α2M by inducing changes in the secondary structure of the protein.

scholarly journals Experiments on Energy-Efficient Evaporative Cooling Systems for Poultry Farm Application in Multan (Pakistan)

2021 ◽  
Vol 13 (5) ◽  
pp. 2836
Author(s):  
Khawar Shahzad ◽  
Muhammad Sultan ◽  
Muhammad Bilal ◽  
Hadeed Ashraf ◽  
Muhammad Farooq ◽  
...  
Keyword(s):  
Heat Stress ◽  
Low Cost ◽  
Evaporative Cooling ◽  
Thermal Exposure ◽  
Climatic Conditions ◽  
The Body ◽  
Dew Point ◽  
Sweat Glands ◽  
Cooling Systems ◽  
Humidity Index

Poultry are one of the most vulnerable species of its kind once the temperature-humidity nexus is explored. This is so because the broilers lack sweat glands as compared to humans and undergo panting process to mitigate their latent heat (moisture produced in the body) in the air. As a result, moisture production inside poultry house needs to be maintained to avoid any serious health and welfare complications. Several strategies such as compressor-based air-conditioning systems have been implemented worldwide to attenuate the heat stress in poultry, but these are not economical. Therefore, this study focuses on the development of low-cost and environmentally friendly improved evaporative cooling systems (DEC, IEC, MEC) from the viewpoint of heat stress in poultry houses. Thermodynamic analysis of these systems was carried out for the climatic conditions of Multan, Pakistan. The results appreciably controlled the environmental conditions which showed that for the months of April, May, and June, the decrease in temperature by direct evaporative cooling (DEC), indirect evaporative cooling (IEC), and Maisotsenko-Cycle evaporative cooling (MEC) systems is 7–10 °C, 5–6.5 °C, and 9.5–12 °C, respectively. In case of July, August, and September, the decrease in temperature by DEC, IEC, and MEC systems is 5.5–7 °C, 3.5–4.5 °C, and 7–7.5 °C, respectively. In addition, drop in temperature-humidity index (THI) values by DEC, IEC, and MEC is 3.5–9 °C, 3–7 °C, and 5.5–10 °C, respectively for all months. Optimum temperature and relative humidity conditions are determined for poultry birds and thereby, systems’ performance is thermodynamically evaluated for poultry farms from the viewpoint of THI, temperature-humidity-velocity index (THVI), and thermal exposure time (ET). From the analysis, it is concluded that MEC system performed relatively better than others due to its ability of dew-point cooling and achieved THI threshold limit with reasonable temperature and humidity indexes.

Voice In Ear

2021 ◽  
Vol 5 (1) ◽  
pp. 1-25
Author(s):  
Yang Gao ◽  
Yincheng Jin ◽  
Jagmohan Chauhan ◽  
Seokmin Choi ◽  
Jiyang Li ◽  
...  
Keyword(s):  
User Authentication ◽  
Low Cost ◽  
The Body ◽  
Ear Canal ◽  
Replay Attacks ◽  
Increasing Demand ◽  
The Right ◽  
Sound Conduction ◽  
Enrollment Data ◽  
Secure Authentication

With the rapid growth of wearable computing and increasing demand for mobile authentication scenarios, voiceprint-based authentication has become one of the prevalent technologies and has already presented tremendous potentials to the public. However, it is vulnerable to voice spoofing attacks (e.g., replay attacks and synthetic voice attacks). To address this threat, we propose a new biometric authentication approach, named EarPrint, which aims to extend voiceprint and build a hidden and secure user authentication scheme on earphones. EarPrint builds on the speaking-induced body sound transmission from the throat to the ear canal, i.e., different users will have different body sound conduction patterns on both sides of ears. As the first exploratory study, extensive experiments on 23 subjects show the EarPrint is robust against ambient noises and body motions. EarPrint achieves an Equal Error Rate (EER) of 3.64% with 75 seconds enrollment data. We also evaluate the resilience of EarPrint against replay attacks. A major contribution of EarPrint is that it leverages two-level uniqueness, including the body sound conduction from the throat to the ear canal and the body asymmetry between the left and the right ears, taking advantage of earphones' paring form-factor. Compared with other mobile and wearable biometric modalities, EarPrint is a low-cost, accurate, and secure authentication solution for earphone users.

scholarly journals Cytokines as Biomarkers and Their Respective Clinical Cutoff Levels

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Rebecca N. Monastero ◽  
Srinivas Pentyala
Keyword(s):  
Tumor Necrosis ◽  
Inflammatory Diseases ◽  
Low Cost ◽  
The Body ◽  
Tumor Necrosis Factors ◽  
Biochemical Pathways ◽  
Downstream Effects ◽  
Future Work ◽  
Receiver Operator Characteristics ◽  
Cutoff Levels

Cytokines, including interleukins, interferons, tumor necrosis factors, and chemokines, have a variety of pro- and anti-inflammatory effects in the body through a number of biochemical pathways and interactions. Stimuli, actions, interactions, and downstream effects of cytokines have been investigated in more depth in recent years, and clinical research has also been conducted to implicate cytokines in causal patterns in certain diseases. However, particular cutoffs of cytokines as biomarkers for disease processes have not been well studied, and this warrants future work to potentially improve diagnoses for diseases with inflammatory markers. A limited number of studies in this area are reviewed, considering diseases correlated with abnormal cytokine profiles, as well as specific cutoffs at which cytokines have been deemed clinically useful for diagnosing those diseases through Receiver Operator Characteristics modeling. In light of studies such as those discussed in this review, cytokine testing has the potential to support diagnosis due to its lack of invasiveness and low cost, compared to other common types of testing for infections and inflammatory diseases.

scholarly journals Development and evaluation of low-cost walker with trunk support for senior citizen

2017 ◽  
Vol 51 (0) ◽  
Author(s):  
Paloma Hohmann Poier ◽  
Francisco Godke ◽  
José Aguiomar Foggiatto ◽  
Leandra Ulbricht
Keyword(s):  
Senior Citizens ◽  
Low Cost ◽  
Senior Citizen ◽  
Descriptive Study ◽  
The Body ◽  
Two Stage ◽  
Monitoring Time ◽  
Static Body ◽  
Study Development

Abstract OBJECTIVE Develop and evaluate a low-cost walker with trunk support for senior citizens. METHOD Two-stage descriptive study: development of a walker with trunk support and evaluation with fourth age senior citizens. RESULTS Twenty-three fourth age senior citizens were selected. The evaluated criteria were the immediate influence of the walker on the static stabilometry with baropodometer and the evaluation of gait with accelerometers monitoring time and amplitude of the hip movement. There was a significant decrease in the body oscillation of senior citizens with the use of the developed walker, and there were changes in the joint amplitudes of the hip, but they were not significant. CONCLUSION Using low-cost materials, it was possible to develop and equipment that met resistance and effectiveness requirements. The walker interfered in the balance of the senior citizens, reducing significantly the static body oscillation.

Design and operation of a tripod walking robot via dynamics simulation

Robotica ◽  
2010 ◽  
Vol 29 (5) ◽  
pp. 733-743 ◽  
Author(s):  
Conghui Liang ◽  
Hao Gu ◽  
Marco Ceccarelli ◽  
Giuseppe Carbone
Keyword(s):  
Mechanical Design ◽  
Low Cost ◽  
Three Dimensional ◽  
The Body ◽  
Dynamics Simulation ◽  
Walking Ability ◽  
Walking Robot ◽  
Three Dimensional Model ◽  
Software Environment ◽  
Leg Mechanisms

SUMMARYA mechanical design and dynamics walking simulation of a novel tripod walking robot are presented in this paper. The tripod walking robot consists of three 1-degree-of-freedom (DOF) Chebyshev–Pantograph leg mechanisms with linkage architecture. A balancing mechanism is mounted on the body of the tripod walking robot to adjust its center of gravity (COG) during walking for balancing purpose. A statically stable tripod walking gait is performed by synchronizing the motions of the three leg mechanisms and the balancing mechanism. A three-dimensional model has been elaborated in SolidWorks® engineering software environment for a characterization of a feasible mechanical design. Dynamics simulation has been carried out in the MSC.ADAMS® environment with the aim to characterize and to evaluate the dynamic walking performances of the proposed design with low-cost easy-operation features. Simulation results show that the proposed tripod walking robot with proper input torques, gives limited reaction forces at the linkage joints, and a practical feasible walking ability on a flatten ground.

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