scholarly journals Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target

2015 ◽  
Vol 51 (86) ◽  
pp. 15637-15640 ◽  
Author(s):  
A. Faust ◽  
T. Völler ◽  
F. Busch ◽  
M. Schäfers ◽  
J. Roth ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Optical Imaging ◽  
Inflammatory Activity ◽  
Imaging Probe ◽  
Inflammatory Processes ◽  
Molecular Imaging Probe ◽  
Novel Target

We describe the development and first evaluation of a novel S100A9 specific molecular imaging probe (Cy5.5-CES271) for optical imaging of local inflammatory activity in vivo.

An in vivo molecular imaging probe 18F-Annexin B1 for apoptosis detection by PET/CT: preparation and preliminary evaluation

APOPTOSIS ◽  
2012 ◽  
Vol 18 (2) ◽  
pp. 238-247 ◽  
Author(s):  
Ming-Wei Wang ◽  
Fang Wang ◽  
Yu-Jia Zheng ◽  
Ying-Jian Zhang ◽  
Yong-Ping Zhang ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Preliminary Evaluation ◽  
Imaging Probe ◽  
Pet Ct ◽  
Apoptosis Detection ◽  
Molecular Imaging Probe ◽  
Annexin B1

Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis

2020 ◽  
Vol 11 (5) ◽  
pp. 1010-1017 ◽  
Author(s):  
Yuhuan Li ◽  
Fangyun Xin ◽  
Jinming Hu ◽  
Shweta Jagdale ◽  
Thomas P. Davis ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Magnetic Resonance ◽  
Optical Imaging ◽  
Dual Modality ◽  
Imaging Probe ◽  
Molecular Imaging Probe ◽  
Targeted Molecular Imaging

A thrombosis-targeted molecular imaging probe with magnetic resonance (MR) and optical dual-modality capacity using dibromomaleimide (DBM)-bearing polymer-grafted NaGdF4 nanoparticles.

DEVELOPMENT OF MOLECULAR IMAGING PROBE FOR IN VIVO IMAGING MISFOLDED PROTEINS

2012 ◽  
Author(s):  
RYUICHI HARADA ◽  
NOBUYUKI OKAMURA ◽  
SHOZO FURUMOTO ◽  
TAKEO YOSHIKAWA ◽  
YUKITSUKA KUDO ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
In Vivo Imaging ◽  
Misfolded Proteins ◽  
Imaging Probe ◽  
Molecular Imaging Probe

scholarly journals Techniques for Molecular Imaging Probe Design

2011 ◽  
Vol 10 (6) ◽  
pp. 7290.2011.00003 ◽  
Author(s):  
Fred Reynolds ◽  
Kimberly A. Kelly
Keyword(s):  
Molecular Imaging ◽  
Target Selection ◽  
Relevant Information ◽  
Probe Design ◽  
Imaging Probe ◽  
Molecular Imaging Probes ◽  
Genomics And Proteomics ◽  
Imaging Probes ◽  
Molecular Imaging Probe ◽  
Underlying Mechanisms

Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.

Synthesis and evaluation of the targeted binding of RGD-containing PEGylated-PEI/DNA polyplex micelles as radiotracers for a tumor-targeting imaging probe

RSC Advances ◽  
2015 ◽  
Vol 5 (130) ◽  
pp. 107455-107465 ◽  
Author(s):  
Adhimoorthy Prasannan ◽  
Tilahun Ayane Debele ◽  
Hsieh-Chih Tsai ◽  
Chiz-Cheng Chao ◽  
Che-Ping Lin ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Ethylene Glycol ◽  
Tumor Targeting ◽  
Poly Ethylene Glycol ◽  
Imaging Probe ◽  
Poly Ethylene

Polyplex micelles with pEGFP and RGD-modified poly(ethylene glycol)-grafted polyethylenimine (E[c(RGDyK)]2-PEG-g-PEI) and were labeled with 99mTc for the in vivo study as proficient probes for molecular imaging.

scholarly journals Breast cancer cell targeted MR molecular imaging probe: Anti-MUC1 antibody-based magnetic nanoparticles

2017 ◽  
Vol 851 ◽  
pp. 012014 ◽  
Author(s):  
P Moradi Khaniabadi ◽  
A. M. S.A Majid ◽  
M Asif ◽  
B Moradi Khaniabadi ◽  
D Shahbazi-Gahrouei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Magnetic Nanoparticles ◽  
Molecular Imaging ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Imaging Probe ◽  
Molecular Imaging Probe

Recent advances in molecular imaging probes for β-amyloid plaques

MedChemComm ◽  
2015 ◽  
Vol 6 (3) ◽  
pp. 391-402 ◽  
Author(s):  
Masahiro Ono ◽  
Hideo Saji
Keyword(s):  
Molecular Imaging ◽  
Optical Imaging ◽  
Amyloid Plaques ◽  
Recent Advances ◽  
Molecular Imaging Probes ◽  
Imaging Probes ◽  
Β Amyloid ◽  
The Brain

We review recent advances in our development of molecular imaging probes for PET, SPECT, and optical imaging for in vivo detection of β-amyloid plaques in the brain.

Sign in / Sign up

Export Citation Format

Share Document