Application of an ionic-liquid combined with ultrasonic-assisted dispersion ofgold nanoparticles for micro-solid phase extraction of unmetabolized pyridoxine and folic acid in biological fluids prior to high-performance liquid chromatography

RSC Advances ◽  
2015 ◽  
Vol 5 (86) ◽  
pp. 70064-70072 ◽  
Author(s):  
Fahimeh Zare ◽  
Mehrorang Ghaedi ◽  
Ali Daneshfar

A facile and efficient protocol was suggested for the synthesis of gold nanoparticles (Au NPs) and their subsequent transfer to aqueous solution using 1-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, following vigorous shaking with ultrasonic waves.

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