Biodegradable PLGA nanoparticles loaded with hydrophobic drugs: confocal Raman microspectroscopic characterization

2015 ◽  
Vol 3 (18) ◽  
pp. 3677-3680 ◽  
Author(s):  
Hu Yan ◽  
Yi-Fan Hou ◽  
Peng-Fei Niu ◽  
Ke Zhang ◽  
Tatsuya Shoji ◽  
...  
Keyword(s):  
Plga Nanoparticles ◽  
Spectroscopic Technique ◽  
Laser Trapping ◽  
Hydrophobic Drugs ◽  
Raman Spectroscopic ◽  
Confocal Raman ◽  
Individual Nanoparticles ◽  
First Time

PLGA nanoparticles with bicyclol and Br-NBP were for the first time successfully characterized by a laser trapping/confocal Raman spectroscopic technique only using individual nanoparticles.

Laser trapping/confocal Raman spectroscopic characterization of PLGA-PEG nanoparticles

Soft Matter ◽  
2018 ◽  
Vol 14 (40) ◽  
pp. 8090-8094 ◽  
Author(s):  
Jie Yang ◽  
Ruo-Nan Zhang ◽  
Dong-Jie Liu ◽  
Xu Zhou ◽  
Tatsuya Shoji ◽  
...  
Keyword(s):  
Glycolic Acid ◽  
Spectroscopic Characterization ◽  
Plga Nanoparticles ◽  
Laser Trapping ◽  
Poly Ethylene Glycol ◽  
Chemical Methods ◽  
Raman Spectroscopic ◽  
Confocal Raman ◽  
Poly Ethylene

We have immobilized poly(ethylene glycol) (PEG) on the surfaces of poly(lactic-co-glycolic acid) (PLGA) nanoparticles by two different chemical methods, i.e., SOCl2 halogenate-alcoholysis and DCC dehydration. The PEG-immobilized PLGA nanoparticles were precisely characterized by the laser trapping/confocal Raman spectroscope.

scholarly journals Raman spectroscopic detection of interleukin-10 and angiotensin converting enzyme

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Shuo Zhang ◽  
Frederieke A. M. van der Mee ◽  
Roel J. Erckens ◽  
Carroll A. B. Webers ◽  
Tos T. J. M. Berendschot
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Biomedical Applications ◽  
Interleukin 10 ◽  
Spectral Features ◽  
Converting Enzyme ◽  
Raman Spectroscopic ◽  
Non Invasive ◽  
Confocal Raman ◽  
First Time ◽  
Enzyme Characteristic

AbstractIn this report we present a confocal Raman system to identify the unique spectral features of two proteins, Interleukin-10 and Angiotensin Converting Enzyme. Characteristic Raman spectra were successfully acquired and identified for the first time to our knowledge, showing the potential of Raman spectroscopy as a non-invasive investigation tool for biomedical applications.

CsOH and its Lighter Homologues – a Comparison

2014 ◽  
Vol 69 (11-12) ◽  
pp. 1229-1236
Author(s):  
Matthias Wörsching ◽  
Constantin Hoch
Keyword(s):  
Gas Phase ◽  
Room Temperature ◽  
Structure Type ◽  
Alkali Metal Hydroxide ◽  
X Ray ◽  
Raman Spectroscopic ◽  
Cesium Hydroxide ◽  
Free Ion ◽  
The One ◽  
First Time

Abstract Cesium hydroxide, CsOH, was for the first time characterised on the basis of single-crystal data. The structure is isotypic to the one of the room-temperature modification of NaOH and can be derived from the NaCl structure type thus allowing the comparison of all alkali metal hydroxide structures. Raman spectroscopic investigations show the hydroxide anion to behave almost as a free ion as in the gas phase. The X-ray investigations indicate possible H atom positions.

Microplasma synthesized gold nanoparticles for surface enhanced Raman spectroscopic detection of methylene blue

2021 ◽  
Author(s):  
Xuanhe Li ◽  
Liangliang Lin ◽  
Wei-Hung Chiang ◽  
Kuan Chang ◽  
Hujun Xu
Keyword(s):  
Rapid Detection ◽  
Chemical Species ◽  
Spectroscopic Technique ◽  
Trace Level ◽  
Raman Spectroscopic ◽  
Non Invasive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Non Destructive

Surface enhanced Raman scattering (SERS) is a powerful and sensitive spectroscopic technique that allows for rapid detection of trace-level chemical species in a non-invasive and non-destructive manner. In the present...

scholarly journals Natural scientific methods in exploration of reference monuments of the Saka Culture in Kazakh Altai

2020 ◽  
pp. 21-31
Author(s):  
Zainolla Samashev ◽  
Aidos Erbulatovich Chotbaev ◽  
Nikolai Sergeevich Kurganov ◽  
Dmitrii Vasil'evich Pankin ◽  
Anastasiya Valer'evna Povolotskaya ◽  
...  
Keyword(s):  
Spectroscopic Technique ◽  
Organic Substances ◽  
Identification Procedure ◽  
Scientific Methods ◽  
Raman Spectroscopic ◽  
Gold Jewelry ◽  
Material Component ◽  
Modern Natural ◽  
East Kazakhstan ◽  
Subsequent Identification

This article explores the ancient gold jewelry with inlay, which were discovered in the process of archeological studies conducted in Summer 2018 of grave complexes located on the Eleke Sazy Plateau, Tarbagatay Ridge in East Kazakhstan Region in the burial of a young man belonging to aristocratic ancestry. It refers to the Saka culture, and dates back to approximately VIII-VII centuries BC. Among the discovered objects were garments embroidered with gold, quiver with arrows, and a bronze dagger in gold scabbard. This work studied the golden scabbard for dagger. The scabbard consists of several parts attached to a wooden base and decorated with granulation and inlay. In many cases, only traces of inlay remain. Some gems changed in color in the process of degradation, and currently look grey. Micro-samples for the research were selected from the crumbling fragments of inlay obtained in the process of restoration of the item. Modern natural scientific methods allow studying the material component of the objects of cultural heritage. The identification procedure is now available even based on the remaining particles with characteristic sizes that do not exceed tens of microns. Within the framework this research, the author examined the possibility of selecting such micro-samples with subsequent identification. Application of the Raman spectroscopic technique allowed examining the selected micro-samples on the next stage. The complementary methods imply Fourier-transform infrared spectroscopy for studying organic substances the inlay was attached to.

Target induced aggregation of modified Au@Ag nanoparticles for surface enhanced Raman scattering and its ultrasensitive detection of arsenic(iii) in aqueous solution

RSC Advances ◽  
2015 ◽  
Vol 5 (95) ◽  
pp. 77755-77759 ◽  
Author(s):  
Bo Yang ◽  
Xiaochun Chen ◽  
Renyong Liu ◽  
Bianhua Liu ◽  
Changlong Jiang
Keyword(s):  
Aqueous Solution ◽  
Spectroscopic Technique ◽  
Ultrasensitive Detection ◽  
Selective Detection ◽  
Raman Spectroscopic ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Induced Aggregation

A highly sensitive and selective detection of As(iii) was reported by target induced aggregation of nanoparticles enhanced Raman spectroscopic technique.

Confocal Raman Spectroscopic Analysis of Ceramic Hip Joints

2006 ◽  
pp. 1211-1214
Author(s):  
Giuseppe Pezzotti ◽  
Ian C. Clarke ◽  
C. Jobe ◽  
T. Donaldson ◽  
K. Yamamoto ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
Hip Joints ◽  
Raman Spectroscopic ◽  
Confocal Raman ◽  
Raman Spectroscopic Analysis

Confocal Raman spectroscopic study of painted medieval manuscripts

2001 ◽  
Vol 2 (3) ◽  
pp. 191-198 ◽  
Author(s):  
Francesca Magistro ◽  
Domenico Majolino ◽  
Placido Migliardo ◽  
Rosina Ponterio ◽  
MariaTeresa Rodriquez
Keyword(s):  
Spectroscopic Study ◽  
Raman Spectroscopic ◽  
Medieval Manuscripts ◽  
Raman Spectroscopic Study ◽  
Confocal Raman

Evaluation and Mapping of Heat-Shield Flight Temperature and Composition with Raman Spectroscopic Techniques

1995 ◽  
Vol 49 (5) ◽  
pp. 598-604 ◽  
Author(s):  
D. R. Tallant ◽  
I. Auerbach ◽  
K. L. Higgins
Keyword(s):  
Spectroscopic Technique ◽  
Heat Shield ◽  
Spectroscopic Techniques ◽  
Raman Spectroscopic ◽  
Detailed Surface ◽  
Post Test ◽  
Composition Profiles ◽  
Maximum Temperatures

A Raman spectroscopic technique has been developed which can measure the maximum temperatures experienced by charring heat-shield materials and determine their post-test compositions (char, pyrolysis zone, and virgin resin). The technique has the capabilities of analyzing circular areas less than 0.1 mm in diameter or rectangles 0.1 mm in width and 2 mm in length. It can provide fine detailed surface and internal mappings and perform the analyses rapidly and conveniently in the laboratory following testing or flight recovery. Representative plots of temperature and composition profiles are provided. The data are compared with computations from the Charring Material Ablation (CMA) code.

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