Label-free quantification of cell-penetrating peptide translocation into liposomes

2016 ◽  
Vol 8 (23) ◽  
pp. 4608-4616 ◽  
Author(s):  
Marie-Lise Jobin ◽  
Isabel D. Alves
Keyword(s):  
Small Molecules ◽  
Lipid Membranes ◽  
Cell Penetrating Peptides ◽  
Cell Penetrating Peptide ◽  
Label Free ◽  
Label Free Quantification ◽  
Cell Penetrating ◽  
Free Quantification ◽  
Peptide Translocation

Cell penetrating peptides (CPPs) are small molecules capable of crossing lipid membranes and transporting cargos of varied sizes and nature inside cells.

Enhanced oral absorption of insulin using colon-specific nanoparticles co-modified with amphiphilic chitosan derivatives and cell-penetrating peptides

2019 ◽  
Vol 7 (4) ◽  
pp. 1493-1506 ◽  
Author(s):  
Feng Guo ◽  
Ting Ouyang ◽  
Taoxing Peng ◽  
Xiuying Zhang ◽  
Baogang Xie ◽  
...  
Keyword(s):  
Oral Absorption ◽  
Cell Penetrating Peptides ◽  
Cell Penetrating Peptide ◽  
Chitosan Derivative ◽  
Chitosan Derivatives ◽  
Cell Penetrating

In this study, amphipathic chitosan derivative (ACS) and cell-penetrating peptide (CPP) co-modified colon-specific nanoparticles (CS-CPP NPs) were prepared and evaluated.

scholarly journals Spectral Clustering Improves Label-Free Quantification of Low-Abundant Proteins

2019 ◽  
Vol 18 (4) ◽  
pp. 1477-1485 ◽  
Author(s):  
Johannes Griss ◽  
Florian Stanek ◽  
Otto Hudecz ◽  
Gerhard Dürnberger ◽  
Yasset Perez-Riverol ◽  
...  
Keyword(s):  
Spectral Clustering ◽  
Label Free ◽  
Label Free Quantification ◽  
Free Quantification

scholarly journals siRNA suppression of hTERT using activatable cell-penetrating peptides in hepatoma cells

2015 ◽  
Vol 35 (2) ◽  
Author(s):  
Hua Li ◽  
Jiwen He ◽  
Huimin Yi ◽  
Guoan Xiang ◽  
Kaiyun Chen ◽  
...  
Keyword(s):  
Hepatoma Cells ◽  
Cell Penetrating Peptides ◽  
Matrix Metalloproteinase 2 ◽  
Cell Penetrating Peptide ◽  
G1 Arrest ◽  
Telomerase Reverse Transcriptase ◽  
Human Telomerase Reverse Transcriptase ◽  
Htert Gene ◽  
Cell Penetrating ◽  
Human Telomerase

In the present study, we delivered human telomerase reverse transcriptase (hTERT) siRNA into SMMC-7721 hepatoma cells using a matrix metalloproteinase-2 (MMP2)-activatable cell-penetrating peptide (aCPP). The siRNA subsequently induced down-regulation of the hTERT gene and G1-arrest, implicating the utility of this delivery system in cancer therapy.

Global Analysis of Protein Expression in A549 Cells After Prolonged Nicotine Exposure by Using Label-free Quantification

2021 ◽  
Vol 41 (8) ◽  
pp. 3833-3842
Author(s):  
SASIKARN KOMKLEOW ◽  
CHURAT WEERAPHAN ◽  
DARANEE CHOKCHAICHAMNANKIT ◽  
PAPADA CHAISURIYA ◽  
CHRIS VERATHAMJAMRAS ◽  
...  
Keyword(s):  
Protein Expression ◽  
Global Analysis ◽  
A549 Cells ◽  
Nicotine Exposure ◽  
Label Free ◽  
Label Free Quantification ◽  
Free Quantification

Label-Free Quantification of Anticancer Drug Imatinib in Human Plasma with Surface Enhanced Raman Spectroscopy

2018 ◽  
Vol 90 (21) ◽  
pp. 12670-12677 ◽  
Author(s):  
Stefano Fornasaro ◽  
Alois Bonifacio ◽  
Elena Marangon ◽  
Mauro Buzzo ◽  
Giuseppe Toffoli ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Human Plasma ◽  
Anticancer Drug ◽  
Surface Enhanced Raman Spectroscopy ◽  
Label Free ◽  
Label Free Quantification ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Free Quantification

Label-free quantification of asymmetric cancer-cell filopodium activities in a multi-gradient chip

Lab on a Chip ◽  
2009 ◽  
Vol 9 (7) ◽  
pp. 884 ◽  
Author(s):  
Tsi-Hsuan Hsu ◽  
Meng-Hua Yen ◽  
Wei-Yu Liao ◽  
Ji-Yen Cheng ◽  
Chau-Hwang Lee
Keyword(s):  
Cancer Cell ◽  
Label Free ◽  
Label Free Quantification ◽  
Free Quantification

scholarly journals A comparison of acyl-moieties for noncovalent functionalization of PLGA and PEG-PLGA nanoparticles with a cell-penetrating peptide

RSC Advances ◽  
2021 ◽  
Vol 11 (57) ◽  
pp. 36116-36124
Author(s):  
Omar Paulino da Silva Filho ◽  
Muhanad Ali ◽  
Rike Nabbefeld ◽  
Daniel Primavessy ◽  
Petra H. Bovee-Geurts ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Plga Nanoparticles ◽  
Cell Penetrating Peptides ◽  
Cell Penetrating Peptide ◽  
Noncovalent Functionalization ◽  
Cell Penetrating ◽  
A Cell

Noncovalent functionalization with acylated cell-penetrating peptides achieves an efficient cellular uptake of PLGA and PEG-PLGA nanoparticles.

scholarly journals Improved Intensity-Based Label-Free Quantification via Proximity-Based Intensity Normalization (PIN)

2014 ◽  
Vol 13 (3) ◽  
pp. 1281-1292 ◽  
Author(s):  
Susan K. Van Riper ◽  
Ebbing P. de Jong ◽  
LeeAnn Higgins ◽  
John V. Carlis ◽  
Timothy J. Griffin
Keyword(s):  
Label Free ◽  
Label Free Quantification ◽  
Free Quantification ◽  
Intensity Normalization

scholarly journals Assessment of Label-Free Quantification in Discovery Proteomics and Impact of Technological Factors and Natural Variability of Protein Abundance

2017 ◽  
Vol 16 (4) ◽  
pp. 1410-1424 ◽  
Author(s):  
MHD Rami Al Shweiki ◽  
Susann Mönchgesang ◽  
Petra Majovsky ◽  
Domenika Thieme ◽  
Diana Trutschel ◽  
...  
Keyword(s):  
Natural Variability ◽  
Protein Abundance ◽  
Label Free ◽  
Technological Factors ◽  
Label Free Quantification ◽  
Free Quantification
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