One-photon and two-photon stimulation of neurons in a microfluidic culture system

Lab on a Chip ◽  
2016 ◽  
Vol 16 (9) ◽  
pp. 1684-1690 ◽  
Author(s):  
Jae Myung Jang ◽  
Jeonghyeon Lee ◽  
Hyeongeun Kim ◽  
Noo Li Jeon ◽  
Woonggyu Jung

A microfluidic device integrated with microelectrode arrays was developed to investigate neural responses to femtosecond light.

2014 ◽  
Vol 2 (8) ◽  
pp. 1100-1110 ◽  
Author(s):  
Ni Kong ◽  
Kaili Lin ◽  
Haiyan Li ◽  
Jiang Chang

Copper and silicon ions exhibited synergy effects in vascularization stimulation by copper-doped calcium silicate bioceramics in a HDF–HUVEC co-culture system.


2011 ◽  
Vol 11 (5) ◽  
pp. 545-556 ◽  
Author(s):  
Huei-Wen Wu ◽  
Chun-Che Lin ◽  
Shiaw-Min Hwang ◽  
Yu-Jen Chang ◽  
Gwo-Bin Lee

2003 ◽  
Vol 94 (1) ◽  
pp. 220-226 ◽  
Author(s):  
Weirong Zhang ◽  
Paul W. Davenport

It has been demonstrated that phrenic nerve afferents project to somatosensory cortex, yet the sensory pathways are still poorly understood. This study investigated the neural responses in the thalamic ventroposteriolateral (VPL) nucleus after phrenic afferent stimulation in cats and rats. Activation of VPL neurons was observed after electrical stimulation of the contralateral phrenic nerve. Direct mechanical stimulation of the diaphragm also elicited increased activity in the same VPL neurons that were activated by electrical stimulation of the phrenic nerve. Some VPL neurons responded to both phrenic afferent stimulation and shoulder probing. In rats, VPL neurons activated by inspiratory occlusion also responded to stimulation on phrenic afferents. These results demonstrate that phrenic afferents can reach the VPL thalamus under physiological conditions and support the hypothesis that the thalamic VPL nucleus functions as a relay for the conduction of proprioceptive information from the diaphragm to the contralateral somatosensory cortex.


2017 ◽  
Vol 8 (6) ◽  
pp. 2110-2114 ◽  
Author(s):  
Yee Yin Ho ◽  
Junya Nakato ◽  
Takafumi Mizushige ◽  
Ryuhei Kanamoto ◽  
Mamoru Tanida ◽  
...  

Stimulation of growth hormone release induced by intraduodenally administered l-ornithine was mediated by the ghrelin system in rats.


RSC Advances ◽  
2014 ◽  
Vol 4 (42) ◽  
pp. 22129-22140 ◽  
Author(s):  
Chelladurai Chellamboli ◽  
Muthiah Perumalsamy

Owing to an increased demand for fuel and the depletion of fossil fuels, an alternative source such as algae is currently being exploited for biofuel production.


1994 ◽  
Vol 21 (4) ◽  
pp. 201-208
Author(s):  
Jun-Ichi Matsushima ◽  
Chihiro Harada ◽  
Noboru Sakai ◽  
Tohru Ifukube ◽  
Makoto Takahashi

Blood ◽  
1975 ◽  
Vol 45 (3) ◽  
pp. 427-433 ◽  
Author(s):  
DH Chui ◽  
BV Loyer

Abstract Adult SI/SI-d mutant mice have severe macrocytic, normochromic anemia. Moreover these animals are unresponsive to the stimulation of erythropoietin in vivo. By means of a bone marrow cell suspension culture system, the present investigation shows that in adult SI/SI-d marrow, there are cells capable of responding in vitro to erythropoietin in a normal fashion. Moreover, the erythropoietin present in SI/SI-d serum is biologically active in vitro without any prior biochemical modification. These observations support the suggestion that there is a defect in differentiation in the erythroid cell lines of SI/SI-d mice in vivo due to an abnormal hemopoietic microenvironment.


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