scholarly journals Peptide-functionalized gold nanoparticles: versatile biomaterials for diagnostic and therapeutic applications

2017 ◽  
Vol 5 (5) ◽  
pp. 872-886 ◽  
Author(s):  
Jingyi Zong ◽  
Steven L. Cobb ◽  
Neil R. Cameron
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Targeted Drug Delivery ◽  
Potential Application ◽  
Cancer Therapeutics ◽  
Therapeutic Applications ◽  
Functionalized Gold Nanoparticles ◽  
Anti Cancer ◽  
Targeted Drug ◽  
Oligonucleotide Delivery

This review provides an overview of the current methods used for preparing peptide-functionalized GNPs, and discusses the key properties of this class of biomaterial. In particular, their potential application in areas of sensing, targeted drug delivery, anti-cancer therapeutics and oligonucleotide delivery are discussed.

Recent advances in combinatorial cancer therapy via multifunctionalized gold nanoparticles

Nanomedicine ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. 1221-1237
Author(s):  
Touqeer Ahmad ◽  
Rizwana Sarwar ◽  
Ayesha Iqbal ◽  
Uzma Bashir ◽  
Umar Farooq ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Therapeutic Implications ◽  
Therapeutic Applications ◽  
Diagnosis Of Cancer ◽  
Targeted Drug ◽  
Cancerous Cells

The diverse behavior of nanogold in the therapeutic field is related to its unique size and shape. Nanogold offers improvements in modern diagnostic and therapeutic implications, increases disease specificity and targeted drug delivery, and is relatively economical compared with other chemotherapeutic protocols. The diagnosis of cancer and photothermal therapy improve drastically with the implementation of nanotechnology. Different types of nanoparticles, that is, gold silica nanoshells, nanorods and nanospheres of diverse shapes and geometries, are used widely in the photothermal therapy of cancerous cells and nodules. Numerous reviews have been published on the therapeutic applications of gold nanoparticles, but studies on combinatorial applications of nanogold in cancer therapy are limited. This review focuses on the combinatorial cancer therapy using optical properties of nanogold with different shapes and geometries, and their therapeutic applications in cancer diagnosis, photothermal therapy, cancer imaging and targeted drug delivery.

Spontaneous ultra fast synthesis of gold nanoparticles using Punica granatum for cancer targeted drug delivery

2013 ◽  
Vol 106 ◽  
pp. 208-216 ◽  
Author(s):  
Moorthy Ganeshkumar ◽  
Muniram Sathishkumar ◽  
Thangavel Ponrasu ◽  
Murugan Girija Dinesh ◽  
Lonchin Suguna
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Targeted Drug Delivery ◽  
Punica Granatum ◽  
Targeted Drug ◽  
Fast Synthesis

Multifunctional magnetic-gold nanoparticles for efficient combined targeted drug delivery and interstitial photothermal therapy

2019 ◽  
Vol 554 ◽  
pp. 256-263 ◽  
Author(s):  
Nihal S. Elbialy ◽  
Mohamed M. Fathy ◽  
Reem AL-Wafi ◽  
Reem Darwesh ◽  
Umama A. Abdel-dayem ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Targeted Drug

scholarly journals Colorectal cancer stem cells: a review of targeted drug delivery by gold nanoparticles

RSC Advances ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 973-985 ◽  
Author(s):  
Manali Haniti Mohd-Zahid ◽  
Rohimah Mohamud ◽  
Che Azurahanim Che Abdullah ◽  
JitKang Lim ◽  
Halima Alem ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Drug Delivery ◽  
Stem Cells ◽  
Gold Nanoparticles ◽  
Cancer Stem Cells ◽  
Targeted Drug Delivery ◽  
Targeted Drug ◽  
Colorectal Cancer Stem Cells

The proposed schematic mechanism via which 5-fluorouracil-loaded gold nanoparticles conjugated with CD133 antibody target colorectal cancer stem cells.

Biotinylated carboxymethyl chitosan/CaCO3 hybrid nanoparticles for targeted drug delivery to overcome tumor drug resistance

RSC Advances ◽  
2016 ◽  
Vol 6 (73) ◽  
pp. 69083-69093 ◽  
Author(s):  
Jin-Long Wu ◽  
Xiao-Yan He ◽  
Pei-Yuan Jiang ◽  
Meng-Qing Gong ◽  
Ren-Xi Zhuo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Tumor Cells ◽  
Targeted Drug Delivery ◽  
Carboxymethyl Chitosan ◽  
Hybrid Nanoparticles ◽  
Cancer Drug ◽  
Tumor Drug Resistance ◽  
Anti Cancer ◽  
Targeted Drug

A tumor targeted nano-sized self-assembled drug delivery system could efficiently co-deliver an anti-cancer drug and a drug resistance inhibitor to tumor cells and achieve an improved therapeutic efficiency through inhibition of P-gp function.

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