From molecules to macrostructures: recent development of bioinspired hard tissue repair

2017 ◽  
Vol 5 (8) ◽  
pp. 1435-1449 ◽  
Author(s):  
Chunmei Ding ◽  
Zhuoxin Chen ◽  
Jianshu Li
Keyword(s):  
Tissue Repair ◽  
Hard Tissue

This review summarizes the bioinspired strategies for hard tissue repair, ranging from molecule-induced mineralization, to microscale assembly to macroscaffold fabrication.

Soft and hard tissue repair

2008 ◽  
pp. 87-109
Author(s):  
Stephen Young ◽  
Melissa Calvin
Keyword(s):  
Tissue Repair ◽  
Hard Tissue

scholarly journals A review of protein adsorption on bioceramics

2012 ◽  
Vol 2 (3) ◽  
pp. 259-277 ◽  
Author(s):  
Kefeng Wang ◽  
Changchun Zhou ◽  
Youliang Hong ◽  
Xingdong Zhang
Keyword(s):  
Tissue Regeneration ◽  
Protein Interactions ◽  
Tissue Repair ◽  
Cellular Response ◽  
Biological Activities ◽  
Biological Mechanisms ◽  
Hard Tissue ◽  
Coated Layer ◽  
Sense And Respond

Bioceramics, because of its excellent biocompatible and mechanical properties, has always been considered as the most promising materials for hard tissue repair. It is well know that an appropriate cellular response to bioceramics surfaces is essential for tissue regeneration and integration. As the in vivo implants, the implanted bioceramics are immediately coated with proteins from blood and body fluids, and it is through this coated layer that cells sense and respond to foreign implants. Hence, the adsorption of proteins is critical within the sequence of biological activities. However, the biological mechanisms of the interactions of bioceramics and proteins are still not well understood. In this review, we will recapitulate the recent studies on the bioceramic–protein interactions.

Bioactive Composite Coating on Titanium Implants for Hard Tissue Repair

2007 ◽  
Vol 334-335 ◽  
pp. 1249-1252 ◽  
Author(s):  
Jin Ming Wu ◽  
Min Wang ◽  
Akiyoshi Osaka
Keyword(s):  
Composite Coating ◽  
Low Temperatures ◽  
Tissue Repair ◽  
Body Fluid ◽  
Titanium Implants ◽  
Apatite Formation ◽  
Hard Tissue ◽  
Layer Composite ◽  
Titania Layer ◽  
Hydrolysis Of

A bioactive composite coating consisting of one layer of titania and one layer of apatite was formed on Ti substrate. The first layer of crystalline titania was deposited on Ti at low temperatures either through oxidation of Ti by hydrogen peroxide solution or through hydrolysis of TiF4 or TiCl4 solution. It was shown that the crystalline titania, either in the form of anatase or rutile, induced formation of the second layer of apatite in a simulated body fluid. However, the trace elements in the titania layer affected greatly apatite formation. The Cl incorporated in the titania layer did not hinder apatite formation while F did. The two-layer composite coating should enhance bonding of Ti implants to bone tissue.

Bio-inspired calcium phosphate materials for hard-tissue repair

2016 ◽  
pp. 405-442
Author(s):  
E. Cunningham ◽  
G. Walker ◽  
F. Buchanan ◽  
N. Dunne
Keyword(s):  
Calcium Phosphate ◽  
Tissue Repair ◽  
Hard Tissue

Composites for Hard Tissue Repair

2012 ◽  
Author(s):  
Zaleha Mustafa ◽  
K. Elizabeth Tanner
Keyword(s):  
Tissue Repair ◽  
Hard Tissue

scholarly journals Current materials and approaches in biomaterials and in hard tissue repair

2002 ◽  
Vol 10 (3-4) ◽  
pp. 161-162
Author(s):  
Vasıf Hasırcı
Keyword(s):  
Tissue Repair ◽  
Hard Tissue

SLA 3D printing of high quality spine shaped β-TCP bioceramics for the hard tissue repair applications

2020 ◽  
Vol 46 (6) ◽  
pp. 7609-7614 ◽  
Author(s):  
Tianyuan Zhou ◽  
Le Zhang ◽  
Qing Yao ◽  
Yuelong Ma ◽  
Chen Hou ◽  
...  
Keyword(s):  
3D Printing ◽  
Tissue Repair ◽  
Hard Tissue ◽  
High Quality

Preparation and characterization of gelatin–hydroxyapatite composite microspheres for hard tissue repair

2015 ◽  
Vol 57 ◽  
pp. 113-122 ◽  
Author(s):  
Shao Ching Chao ◽  
Ming-Jia Wang ◽  
Nai-Su Pai ◽  
Shiow-Kang Yen
Keyword(s):  
Tissue Repair ◽  
Hard Tissue ◽  
Composite Microspheres ◽  
Hydroxyapatite Composite

Deformation and Fracture of Bone Analogue Biomaterials Having Different Polymer Matrices

2008 ◽  
Vol 47-50 ◽  
pp. 1391-1394
Author(s):  
Min Wang ◽  
Ya Liu ◽  
Chun Ling Au ◽  
Pik Ki Lai ◽  
Lai Yee Leung ◽  
...  
Keyword(s):  
Polymer Composites ◽  
Tissue Repair ◽  
Mechanical Performance ◽  
Mechanical Tests ◽  
Hard Tissue ◽  
Fracture Characteristics ◽  
The Past ◽  
Reinforced Polymer ◽  
Deformation And Fracture ◽  
Biological Assessments

By mimicking the microstructure of human cortical bone, a variety of bioactive particle reinforced polymer composites have been developed for hard tissue repair. Apart from biological assessments, these composites must be fully evaluated in terms of their mechanical performance before they can be used in patients. The bioactive particles in these composites are normally hard (relative to matrix materials) and brittle bioceramics such as hydroxyapatite (HA), tricalcium phosphate (TCP), Bioglass, etc. The matrices can be either “biostable” polymers such as high density polyethylene (HDPE) and polysulfone (PSU) or biodegradable polymers such as polyhydroxybutyrate (PHB) and poly(L-lactide) (PLLA). These polymers on their own possess different mechanical properties and display different deformation behaviours. With the incorporation of various amounts of particulate HA, TCP or Bioglass, the bone analogue polymeric composites exhibit a spectrum of deformation and fracture characteristics. In our systematic studies of HA/HDPE, Bioglass/HDPE, HA/PSU, HA/PHB, TCP/PHB and a few other bone analogues biomaterials over the past fifteen years, mechanical tests were conducted under a variety of loading conditions (tension, compression, bending, torsion, etc.). Comparisons of deformation and fracture behaviours of these composites were made and presented. The insights that have been gained are important for developing other bioactive ceramic-polymer composites.

Synthesis and Properties of Ceramic Foams for Hard Tissue Repair

2001 ◽  
Vol 218-220 ◽  
pp. 413-416 ◽  
Author(s):  
P. Sepulveda ◽  
Ana Helena A. Bressiani ◽  
José Carlos Bressiani ◽  
L. Meseguer ◽  
B. König Jr
Keyword(s):  
Tissue Repair ◽  
Hard Tissue ◽  
Ceramic Foams
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