scholarly journals Bioprocess development for muconic acid production from aromatic compounds and lignin

2018 ◽  
Vol 20 (21) ◽  
pp. 5007-5019 ◽  
Author(s):  
Davinia Salvachúa ◽  
Christopher W. Johnson ◽  
Christine A. Singer ◽  
Holly Rohrer ◽  
Darren J. Peterson ◽  
...  
Keyword(s):  
Aromatic Compounds ◽  
Acid Production ◽  
Process Development ◽  
Bioprocess Development ◽  
Muconic Acid ◽  
Bioreactor Process

This work shows parallel strain and bioreactor process development to improve muconic acid production from aromatic compounds and lignin.

scholarly journals Enhancing muconic acid production from glucose and lignin-derived aromatic compounds via increased protocatechuate decarboxylase activity

2016 ◽  
Vol 3 ◽  
pp. 111-119 ◽  
Author(s):  
Christopher W. Johnson ◽  
Davinia Salvachúa ◽  
Payal Khanna ◽  
Holly Smith ◽  
Darren J. Peterson ◽  
...  
Keyword(s):  
Aromatic Compounds ◽  
Acid Production ◽  
Decarboxylase Activity ◽  
Muconic Acid

scholarly journals Oxidation Reactions of Marchantin A Trimethyl Ether and Some Aromatic Compounds using m-Chloroperbenzoic Acid. Formation of Muconic Acid Ester and m-Chlorobenzoate

1999 ◽  
Vol 23 (8) ◽  
pp. 470-471
Author(s):  
Motoo Tori ◽  
Masakazu Sono ◽  
Keiko Takikawa ◽  
Reiko Matsuda ◽  
Masao Toyota ◽  
...  
Keyword(s):  
Aromatic Ring ◽  
Methyl Ether ◽  
Aromatic Compounds ◽  
Acid Ester ◽  
Acid Formation ◽  
Oxidation Reactions ◽  
Muconic Acid ◽  
Trimethyl Ether

On treatment with m-chloroperbenzoic acid, dihydroeugenol methyl ether and marchantin A trimethyl ether afford muconic acid ester derivatives by oxidation of the aromatic ring as well as hydroxylated derivatives; the m-chlorobenzoate of the dihydroeugenol derivative is also observed for the former.

scholarly journals Nitrogen-containing aromatic compounds: quantitative analysis using gas chromatography with nitrogen phosphorus detector

2021 ◽  
Author(s):  
Yuan Rao ◽  
Arno de Klerk
Keyword(s):  
Gas Chromatography ◽  
Quantitative Analysis ◽  
Aromatic Compounds ◽  
Process Development ◽  
Complex Mixtures ◽  
Response Factors ◽  
Cyanide Anion ◽  
Nitrogen Phosphorus Detector ◽  
Assurance Process ◽  
Nitrogen Containing Compounds

AbstractThe nitrogen-containing aromatic compounds found in the petrochemical industry are varied and extend beyond classes such as the anilines, pyrroles and pyridines. Quantification of these nitrogen-containing compounds that may occur in complex mixtures has practical application for quality assurance, process development and the evaluation of conversion processes. Selective detection of nitrogen-containing species in complex mixtures is possible by making use of gas chromatography coupled with a nitrogen phosphorous detector (GC-NPD), which is also called a thermionic detector. Despite the linearity of the NPD response to individual nitrogen-containing compounds, the response factor is different for different compounds and even isomers of the same species. Quantitative analysis using an NPD requires species-specific calibration. The reason for the sensitivity of the NPD to structure is related to the ease of forming the cyano-radical that is ionized to the cyanide anion, which is detected. The operation of the NPD was related to the processes of pyrolysis and subsequent ionization. It was possible to offer plausible explanations for differences in response factors for isomers based on pyrolysis chemistry. Due to this relationship, the NPD response can in the same way be used to provide information of practical relevance beyond its analytical value and a few possible applications were outlined.

scholarly journals Bio Adipic Acid Production from Sodium Muconate and Muconic Acid: A Comparison of two Systems

ChemCatChem ◽  
2019 ◽  
Vol 11 (13) ◽  
pp. 3075-3084 ◽  
Author(s):  
Sofia Capelli ◽  
Davide Motta ◽  
Claudio Evangelisti ◽  
Nikolaos Dimitratos ◽  
Laura Prati ◽  
...  
Keyword(s):  
Adipic Acid ◽  
Acid Production ◽  
Muconic Acid ◽  
Two Systems

Zum stoffwechsel von aromaten, II. über die muconsäurespaltung von einfachen o-diphenolen / on the metabolism of aromatic compounds, ii * the muconic acid scission of simple o-diphenols

1973 ◽  
Vol 28 (11-12) ◽  
pp. 662-674 ◽  
Author(s):  
Günther Schulz ◽  
Erich Hecker
Keyword(s):  
Acetic Acid ◽  
Sulfuric Acid ◽  
Ethyl Acetate ◽  
Peracetic Acid ◽  
Aromatic Compounds ◽  
Time Course ◽  
Protocatechuic Acid ◽  
Uv Light ◽  
Steric Effects ◽  
Muconic Acid

Abstract The preparation of substituted cis,cis-muconic acids by oxidative ring scission of simple o-di-phenols with peracetic acid is investigated. Scission of pyrocatechol (1) to cis,cis-muconic acid (2) gives optimal yields, if acetic acid or ethyl acetate is used as solvent and if the solution is 15-20% with respect to sulfuric acid free peracetic acid comprising a one molar excess of oxidant. Under similar conditions, 3-tosylamino-pyrocatechol yields with peracetic acid the hitherto unknown α-tosylamino-cis,cis-muconic caid (18). 18 may be converted to α-tosylamino-traras,trans-muconic acid (19) by means of iodine, UV light or heating. From protocatechuic acid (4) under similar conditions not β-carboxy-cis,cis-muconic acid (5) is obtained, but rather β-carboxy-mucono-lactone (6 b, γ-carboxymethyl-β-carboxy-Δα-butenolide). As yet, this lactone has been accessible only from an isomer of β-carboxy-cis,cis-muconic acid, the latter being obtainable by enzymatic scission of protocatechuic acid (4). Steric effects are responsible for both, the formation of the free cis,cis-muconic acids 2 and 18 from pyrocatechol (1) and α-tosylamino-pyrocatechol, and the formation of the γ-lactone 6 b instead of β -carboxy-cis,cis-muconic acid by scission of protocatechuic acid (4). The time course of the reactions shows that - compared to pyrocatechol (1) - a 3-tosylamino-group enhances the peracetic acid scission, whereas a 4-carboxygroup as in 4 slows it down

Development of a Plasmid-Free Biosynthetic Pathway for Enhanced Muconic Acid Production in Pseudomonas chlororaphis HT66

2018 ◽  
Vol 7 (4) ◽  
pp. 1131-1142 ◽  
Author(s):  
Songwei Wang ◽  
Muhammad Bilal ◽  
Yuanna Zong ◽  
Hongbo Hu ◽  
Wei Wang ◽  
...  
Keyword(s):  
Acid Production ◽  
Biosynthetic Pathway ◽  
Pseudomonas Chlororaphis ◽  
Muconic Acid

scholarly journals Recent Advances in Microbial Production of cis,cis-Muconic Acid

Biomolecules ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1238 ◽  
Author(s):  
Sisun Choi ◽  
Han-Na Lee ◽  
Eunhwi Park ◽  
Sang-Jong Lee ◽  
Eung-Soo Kim
Keyword(s):  
Metabolic Pathway ◽  
Aromatic Compounds ◽  
Terephthalic Acid ◽  
De Novo ◽  
Vital Role ◽  
Chemical Processes ◽  
Muconic Acid ◽  
Production Strategies ◽  
Culture Process ◽  
Foreign Genes

cis,cis-Muconic acid (MA) is a valuable C6 dicarboxylic acid platform chemical that is used as a starting material for the production of various valuable polymers and drugs, including adipic acid and terephthalic acid. As an alternative to traditional chemical processes, bio-based MA production has progressed to the establishment of de novo MA pathways in several microorganisms, such as Escherichia coli, Corynebacterium glutamicum, Pseudomonas putida, and Saccharomyces cerevisiae. Redesign of the metabolic pathway, intermediate flux control, and culture process optimization were all pursued to maximize the microbial MA production yield. Recently, MA production from biomass, such as the aromatic polymer lignin, has also attracted attention from researchers focusing on microbes that are tolerant to aromatic compounds. This paper summarizes recent microbial MA production strategies that involve engineering the metabolic pathway genes as well as the heterologous expression of some foreign genes involved in MA biosynthesis. Microbial MA production will continue to play a vital role in the field of bio-refineries and a feasible way to complement various petrochemical-based chemical processes.

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