Application of ZIF-8–graphene oxide sponge to a solid phase extraction method for the analysis of sex hormones in milk and milk products by high-performance liquid chromatography

2019 ◽  
Vol 43 (6) ◽  
pp. 2783-2789 ◽  
Author(s):  
Xuemei Wang ◽  
Juan Wang ◽  
Tongtong Du ◽  
Haixia Kou ◽  
Xinzhen Du ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Graphene Oxide ◽  
Extraction Method ◽  
High Performance ◽  
Preparation Method ◽  
Solid Phase ◽  
Phase Extraction ◽  
One Pot ◽  
Zeolitic Imidazolate Framework ◽  
Milk Products

A zeolitic imidazolate framework-8 (ZIF-8) incorporating a graphene oxide sponge (GOS) nanocomposite (ZIF-8–GOS) was synthesized successfully by a simple one-pot preparation method.

scholarly journals Magnetic-Dispersive Solid Phase Extraction Based on Graphene Oxide–Fe3O4 Nanocomposites Followed by High Performance Liquid Chromatography-Fluorescence for the Preconcentration and Determination of Terazosin Hydrochloride in Human Plasma

2019 ◽  
Vol 58 (2) ◽  
pp. 178-186 ◽  
Author(s):  
Yaser Pashaei ◽  
Bahram Daraei ◽  
Maryam Shekarchi
Keyword(s):  
High Performance Liquid Chromatography ◽  
Graphene Oxide ◽  
Human Plasma ◽  
High Performance ◽  
Solid Phase ◽  
Phase Extraction ◽  
Plasma Samples ◽  
Dispersive Solid Phase Extraction ◽  
X Ray

Abstract In the present study, a facile modified impregnation method was employed to synthesize superparamagnetic graphene oxide–Fe3O4 (GO–Fe3O4) nanocomposites. Based on the GO–Fe3O4 as adsorbent, a simple and fast magnetic-dispersive solid phase extraction followed by high performance liquid chromatography with fluorescence detection (M-dSPE–HPLC–FL) method was established and validated for the preconcentration and determination of terazosin hydrochloride (TRZ) in human plasma samples. The obtained nanomaterials were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy and vibrating sample magnetometry. Different parameters affecting the extraction efficiency, such as sample pH, amount of sorbent, extraction time, elution solvent and its volume and desorption time, were evaluated and optimized. The linearity of the proposed method was excellent over the range 0.3–50.0 ng mL−1 with an acceptable coefficient of determination (R2 = 0.9989). The limit of quantification and limit of detection were found to be 0.3 and 0.09 ng mL−1, respectively, and the preconcentration factor of 10 was achieved. Intra- and inter-day precision expressed as relative standard deviation (RSD %, n = 6) were between 2.2–3.8% and 4.7–6.4%, respectively. Accuracy, estimated by recovery assays, was 97.7–106.6% with RSD ≤ 5.2%. Ultimately, the applicability of the method was successfully confirmed by the extraction and determination of TRZ in human plasma samples.

scholarly journals Trace determination of chlorpheniramine in human plasma using magnetic dispersive solid-phase extraction based on a graphene oxide/Fe3O4@polythionine nanocomposite combined with high-performance liquid chromatography

RSC Advances ◽  
2017 ◽  
Vol 7 (84) ◽  
pp. 53210-53218 ◽  
Author(s):  
Maryam Ahmadi Daryakenary ◽  
Mohsen Zeeb
Keyword(s):  
High Performance Liquid Chromatography ◽  
Graphene Oxide ◽  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Human Plasma ◽  
High Performance ◽  
Solid Phase ◽  
Phase Extraction ◽  
Dispersive Solid Phase Extraction

Graphene oxide/Fe3O4@polythionine (GO/Fe3O4@PTh) nanocomposite was fabricated for magnetic dispersive solid-phase extraction and high-performance liquid chromatography-ultraviolent detection (HPLC) of chlorpheniramine in human plasma.

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