Recent advances in nanomaterials for enhanced photothermal therapy of tumors

Nanoscale ◽  
2018 ◽  
Vol 10 (48) ◽  
pp. 22657-22672 ◽  
Author(s):  
Jing-Jing Hu ◽  
Ying-Jia Cheng ◽  
Xian-Zheng Zhang
Keyword(s):  
Therapeutic Efficacy ◽  
Photothermal Therapy ◽  
Tumor Treatment ◽  
Recent Advances

Recent advances in nanomaterials for enhanced therapeutic efficacy of photothermal therapy in tumor treatment were highlighted.

Recent advances in MoS2-based photothermal therapy for cancer and infectious disease treatment

2020 ◽  
Vol 8 (27) ◽  
pp. 5793-5807
Author(s):  
Jinping Shi ◽  
Juan Li ◽  
Yan Wang ◽  
Jingjing Cheng ◽  
Can Yang Zhang
Keyword(s):  
Infectious Disease ◽  
Side Effects ◽  
Therapeutic Efficacy ◽  
Photothermal Therapy ◽  
Disease Treatment ◽  
Recent Advances

MoS2-based PTT with high therapeutic efficacy and minimal side-effects could show potential for improving cancer and infectious disease treatments.

Recent advances in the development of metal-organic framework-based gas nanoplatforms for synergistic cancer therapy

2021 ◽  
Author(s):  
Yong Yao ◽  
Danni Jing ◽  
Jianan Zhang ◽  
Youyou Huang ◽  
Xiru Qin ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Therapeutic Efficacy ◽  
Metal Organic Framework ◽  
Research Field ◽  
Tumor Site ◽  
Recent Advances ◽  
Metal Organic ◽  
Organic Framework

Featuring high therapeutic efficacy, biocompatibility, and biosafety, gas therapy as a burgeoning and promising research field has attracted considerable attention in biomedicine. However, the lack of the tumor site accumulation...

The nanomedicine system has successfully inhibited tumor neovascularization using gene silencing, chemotherapy, photothermal therapy, and other therapies

2021 ◽  
Author(s):  
Moataz Dowaidar
Keyword(s):  
Treatment Outcome ◽  
Gene Silencing ◽  
Large Volume ◽  
Photothermal Therapy ◽  
Tumor Model ◽  
Vascular Wall ◽  
Tumor Treatment ◽  
Physical Methods ◽  
Vascular Disruption ◽  
Tumor Neovascularization

Customized nanomedicines can be used in a variety of ways, including angiogenesis suppression, vascular disruption, and vascular infarction. In the angiogenesis suppression approach, VEGF, VEGFR, mTOR, EGFR, bFGF, ROS, and other components have become promising therapeutic targets. The nanomedicine system has successfully inhibited tumor neovascularization using gene silencing, chemotherapy, photothermal therapy, and other therapies. In the vascular disruption approach, VDAs supplied by nanomaterials were bonded with the bonding sites of CA4, COL, PTX, and other medications on microtubules to promote rapid disintegration of tumor vascular wall cells. Combining many medicines increased the tumor treatment outcome even more. For example, disruption of tumor blood arteries caused by nanoparticle-mediated physical methods combined with chemotherapy resulted in effective treatment in a large volume tumor model. The vascular infarction methodology uses a variety of carriers, including nanoparticles, DNA nanorobots, platelet membranes, and others, to carry thrombin, tTF, and other drugs to generate local thrombosis and provide safe and effective tumor treatment.

scholarly journals Psychedelics and hypnosis: Commonalities and therapeutic implications

2018 ◽  
Vol 32 (7) ◽  
pp. 732-740 ◽  
Author(s):  
Clément E Lemercier ◽  
Devin B Terhune
Keyword(s):  
Acute Phase ◽  
Therapeutic Efficacy ◽  
Therapeutic Action ◽  
Therapeutic Implications ◽  
Recent Advances ◽  
Therapeutic Outcomes ◽  
Potential Efficacy

Background: Recent research on psychedelics and hypnosis demonstrates the value of both methods in the treatment of a range of psychopathologies with overlapping applications and neurophenomenological features. The potential of harnessing the power of suggestion to influence the phenomenological response to psychedelics toward more therapeutic action has remained unexplored in recent research and thereby warrants empirical attention. Aims: Here we aim to elucidate the phenomenological and neurophysiological similarities and dissimilarities between psychedelic states and hypnosis in order to revisit how contemporary knowledge may inform their conjunct usage in psychotherapy. Methods: We review recent advances in phenomenological and neurophysiological research on psychedelics and hypnosis, and we summarize early investigations on the coupling of psychedelics and hypnosis in scientific and therapeutic contexts. Results/outcomes: We highlight commonalities and differences between psychedelics and hypnosis that point to the potential efficacy of combining the two in psychotherapy. We propose multiple research paths for coupling these two phenomena at different stages in the preparation, acute phase and follow-up of psychedelic-assisted psychotherapy in order to prepare, guide and integrate the psychedelic experience with the aim of enhancing therapeutic outcomes. Conclusions/interpretation: Harnessing the power of suggestion to modulate response to psychedelics could enhance their therapeutic efficacy by helping to increase the likelihood of positive responses, including mystical-type experiences.

Leveraging BODIPY nanomaterials for enhanced tumor photothermal therapy

2021 ◽  
Author(s):  
Chong Ma ◽  
Tao Zhang ◽  
Zhigang Xie
Keyword(s):  
Side Effects ◽  
Photothermal Therapy ◽  
Tumor Treatment ◽  
The Past

In the past ten years, photothermal therapy (PTT) has attracted widespread attention in tumor treatment due to its non-invasiveness and little side effects. PTT utilize the heat produced by photothermal...

Photothermal Therapy Combined with Light-Induced Generation of Alkyl Radicals for Enhanced Efficacy of Tumor Treatment

2020 ◽  
Vol 2 (10) ◽  
pp. 4188-4194
Author(s):  
Qihang Wu ◽  
Jinfeng Han ◽  
Chaonan Li ◽  
Tingting Sun ◽  
Zhigang Xie
Keyword(s):  
Photothermal Therapy ◽  
Tumor Treatment ◽  
Alkyl Radicals

Recent advances of polyoxometalates in multi-functional imaging and photothermal therapy

2020 ◽  
Vol 8 (36) ◽  
pp. 8189-8206 ◽  
Author(s):  
Xueping Kong ◽  
Guofeng Wan ◽  
Bao Li ◽  
Lixin Wu
Keyword(s):  
Functional Imaging ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Imaging Techniques ◽  
Tumor Therapy ◽  
Recent Advances ◽  
Bio Imaging

The recent advances of polyoxometalate clusters in terms of near infrared photothermal properties for targeted tumor therapy have been summarized while the combined applications with various bio-imaging techniques and chemotherapies are reviewed.

scholarly journals Research on Targeted Thermal Effect of Molybdenum Disulfide Nanosheets Modified by Nucleic Acid Aptamers

2020 ◽  
Vol 185 ◽  
pp. 04003
Author(s):  
Bo pang ◽  
Lihong Jin ◽  
Liying Wang
Keyword(s):  
Nucleic Acid ◽  
Molybdenum Disulfide ◽  
Therapeutic Effect ◽  
Photothermal Therapy ◽  
Effective Concentration ◽  
Tumor Treatment ◽  
Nucleic Acid Aptamers ◽  
Low Toxicity ◽  
Good Biocompatibility ◽  
Molybdenum Disulfide Nanosheets

In this paper, the surface of molybdenum disulfide nanosheets synthesized by hydrothermal method was modified with bovine serum albumin (BSA) and nucleic acid aptamers in order to construct a photothermal system with high target recognition, stable size, good biocompatibility and low toxicity Nano material molybdenum disulfide; Under 808 nm laser irradiation, suitable functionalized molybdenum disulfide nanosheets can produce singlet oxygen at an effective concentration for photodynamic therapy, and at the same time, photothermal therapy can also be used to achieve synergistic therapy and the therapeutic effect is more excellent. This shows that such functionalized molybdenum disulfide nanosheets have excellent therapeutic effect and great potential in tumor treatment.

scholarly journals Recent progress in H2S activated diagnosis and treatment agents

RSC Advances ◽  
2019 ◽  
Vol 9 (58) ◽  
pp. 33578-33588 ◽  
Author(s):  
Xiaodong Wang ◽  
Lu An ◽  
Qiwei Tian ◽  
Kuili Cui
Keyword(s):  
Recent Progress ◽  
Diagnosis And Treatment ◽  
Tumor Treatment ◽  
Recent Advances

This review summarizes the recent advances in H2S detection probes and H2S-activated tumor treatment agents.

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