A highly sensitive and selective two-photon fluorescent probe for real-time sensing of cytochrome P450 1A1 in living systems

We designed and developed a highly sensitive and selective two-photon fluorescent probe for real-time tracking CYP1A1 activity in cancer tissues and zebrafish.

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A highly selective ratiometric two-photon fluorescent probe for human cytochrome P450 1A1 and its application

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2016.10.159 ◽

2017 ◽

Vol 32 (1) ◽

pp. S37

Author(s):

Ziru Dai ◽

Guang-Bo Ge ◽

Ling Yang ◽

Lei Feng ◽

Jing-Nan Cui ◽

...

Keyword(s):

Cytochrome P450 ◽

Fluorescent Probe ◽

Cytochrome P450 1A1 ◽

Two Photon ◽

Human Cytochrome

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A highly selective ratiometric fluorescent probe based on naphthalimide for detection and imaging of CYP1A1 in living cells and zebrafish

The Analyst ◽

10.1039/c9an01767d ◽

2019 ◽

Vol 144 (24) ◽

pp. 7390-7397 ◽

Cited By ~ 6

Author(s):

Hefang Ji ◽

Xiuxuan Zhang ◽

Yanpeng Dai ◽

Tianzi Xue ◽

Saima Misal ◽

...

Keyword(s):

Cytochrome P450 ◽

Real Time ◽

Fluorescent Probe ◽

Significant Role ◽

Biological Systems ◽

Living Cells ◽

Cytochrome P450 1A1 ◽

Real Time Monitoring ◽

Practical Tool ◽

Ratiometric Fluorescent Probe

Real-time monitoring of the cytochrome P450 1A1 (CYP1A1) activity in complex biological systems via a practical tool is highly sought after because of its significant role in the metabolism and bioactivation of various xenobiotics.

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Highly Sensitive Naphthalene-Based Two-Photon Fluorescent Probe for in Situ Real-Time Bioimaging of Ultratrace Cyclooxygenase-2 in Living Biosystems

Analytical Chemistry ◽

10.1021/ac501944y ◽

2014 ◽

Vol 86 (18) ◽

pp. 9131-9138 ◽

Cited By ~ 36

Author(s):

Hua Zhang ◽

Jiangli Fan ◽

Kui Wang ◽

Jing Li ◽

Caixia Wang ◽

...

Keyword(s):

Real Time ◽

Fluorescent Probe ◽

Cyclooxygenase 2 ◽

Two Photon ◽

Highly Sensitive

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Fluorescence behavior of a unique two-photon fluorescent probe in aggregate and solution states and highly sensitive detection of RNA in water solution and living systems

Chemical Communications ◽

10.1039/c6cc03746a ◽

2016 ◽

Vol 52 (57) ◽

pp. 8838-8841 ◽

Cited By ~ 22

Author(s):

Yong Liu ◽

Fangfang Meng ◽

Longwei He ◽

Xiaoqiang Yu ◽

Weiying Lin

Keyword(s):

Fluorescent Probe ◽

Water Solution ◽

Pure Water ◽

Water Systems ◽

Living Systems ◽

Sensitive Detection ◽

Two Photon ◽

Highly Sensitive ◽

Highly Sensitive Detection ◽

First Time

In this work, we developed a unique fluorescent probe HVC-6 for highly sensitive detection of RNA in pure water systems and living systems by aggregation–disaggregation of the probe for the first time.

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A sensitive two-photon ratiometric fluorescent probe for γ-glutamyltranspeptidase activity detection and imaging in living cells and cancer tissues

New Journal of Chemistry ◽

10.1039/c8nj00520f ◽

2018 ◽

Vol 42 (7) ◽

pp. 5403-5407 ◽

Cited By ~ 6

Author(s):

Wei Liu ◽

Bo Huang ◽

Zong-Xuan Tong ◽

Shuanglong Wang ◽

Yi-Jin Li ◽

...

Keyword(s):

Fluorescent Probe ◽

Living Cells ◽

Selective Detection ◽

Activity Detection ◽

Two Photon ◽

Highly Sensitive ◽

Cancer Tissues ◽

Ratiometric Fluorescent Probe

We develop a novel ratiometric two-photon fluorescent probe that allows highly sensitive and selective detection and imaging of γ-glutamyltranspeptidase activities.

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