scholarly journals Metabolomics study of the therapeutic mechanism of a Chinese herbal formula on collagen-induced arthritis mice

RSC Advances ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 3716-3725 ◽  
Author(s):  
Zhen Jin ◽  
Ji-da Zhang ◽  
Xin Wu ◽  
Gang Cao

Wenjinghuoluo (WJHL) prescription, the typical rheumatoid arthritis (RA) treatment compound in traditional Chinese medicine, shows favorable efficacy.

2009 ◽  
Vol 37 (03) ◽  
pp. 411-426 ◽  
Author(s):  
Stevenson Xutian ◽  
Jun Zhang ◽  
Wozniak Louise

Traditional Chinese Medicine (TCM), originating from oriental philosophy and culture, has been developing through a series of special research and experiments with meditation, accumulation of experiences, and a complete comprehension of ancient theories and methods. However, compared with Conventional Western Medicine (CWM), the theory of TCM is complicated and not easily accepted by Westerners. It is important to explore TCM by using modern scientific techniques and theories. Utilizing his frontier experience and up-to-date scientific knowledge, Dr. Qian Xuesen has been trying to incorporate some key principles with the comprehensive understanding of TCM and clarify difficult but important concepts and principles. Some examples are the existence of invisible matter; 'Qi' and 'Qi monism'; the Heart representing the 'whole will' of human beings; the water environment functioning as a fundamental condition of life; the human body being united with nature and universe as one; the spirit and physical body always being considered unified and connected with the five viscera, especially with the Heart; and the Chinese herbal formula working with different principles than CWM drugs. These works are important for understanding the essence of TCM, the promoting of the modernization of TCM theories by means of the latest of achievements in scientific developments, establishing the direction for future medicines with TCM characteristics, uniting Chinese and Western medicines, and exploiting a bright future for the health of mankind.


2015 ◽  
Vol 10 (1-2) ◽  
pp. 316-339 ◽  
Author(s):  
Wen-Hua Kuo

This study explores the social dynamics in promoting traditional Chinese medicine (tcm) drugs by making them acceptable to biomedical markets. It investigates the Consortium for Globalization of Chinese Medicine (cgcm), an organisation based in Hong Kong in pursuit of advancing tcm, and traces the development of the herbal formula phy906, a Chinese herbal product intensively discussed at the cgcm that has been tested according to the us Food and Drug Administration’s regulation for approval. Departing from accounts on the organisation’s success that focus either on its scientific approach or its leader Yung-chi Cheng, this paper argues that it was the synergy between the cgcm and the pursuit of approval for phy906 that contributed to the regulatory globalisation of tcm. In this process, not only organisations like the cgcm are required to streamline efforts for producing globalised tcm; also researchers are needed who, with cultural commitment, seek for transforming tcm to meet biomedical indications.


2016 ◽  
Vol 2016 ◽  
pp. 1-13 ◽  
Author(s):  
Shu-Wen Weng ◽  
Bor-Chyuan Chen ◽  
Yu-Chiao Wang ◽  
Chun-Kai Liu ◽  
Mao-Feng Sun ◽  
...  

Traditional Chinese medicine (TCM) has long been used for patients with psoriasis. This study aimed to investigate TCM usage in patients with psoriasis. We analyzed a cohort of one million individuals representing the 23 million enrollees randomly selected from the National Health Insurance Research Database in Taiwan. We identified 28,510 patients newly diagnosed with psoriasis between 2000 and 2010. Among them, 20,084 (70.4%) patients were TCM users. Patients who were female, younger, white-collar workers and lived in urbanized area tended to be TCM users. The median interval between the initial diagnosis of psoriasis to the first TCM consultation was 12 months. More than half (N=11,609; 57.8%) of the TCM users received only Chinese herbal medicine. Win-qing-yin and Bai-xian-pi were the most commonly prescribed Chinese herbal formula and single herb, respectively. The core prescription pattern comprised Mu-dan-pi, Wen-qing-yin, Zi-cao, Bai-xian-pi, and Di-fu-zi. Patients preferred TCM than Western medicine consultations when they had metabolic syndrome, hepatitis, rheumatoid arthritis, alopecia areata, Crohn’s disease, cancer, depression, fatty liver, chronic airway obstruction, sleep disorder, and allergic rhinitis. In conclusion, TCM use is popular among patients with psoriasis in Taiwan. Future clinical trials to investigate its efficacy are warranted.


2011 ◽  
Vol 134 (2) ◽  
pp. 399-405 ◽  
Author(s):  
Xiaoyan Shen ◽  
Cuixian Li ◽  
Huifang Zhao ◽  
Songhua Li ◽  
Jifan Chen ◽  
...  

1993 ◽  
Vol 21 (02) ◽  
pp. 159-170 ◽  
Author(s):  
Chung-tei Chou ◽  
Wu-Ion Wu ◽  
Mu-Ian Chang ◽  
Deh-ming Chang

The Chinese herbal formula Suching-huo-hsuei-tang (SHT) was studied to evaluate its efficacy and possible mechanism on adjuvant - induced arthritis (AIA) in rats. SHT was extracted with water, butanol and chloroform into 5 different layers. The top 3 layers of SHT showed a significant suppression of AIA and writhing reaction; the top 2 layers suppressed neutrophil chemotaxis and platelet aggregation. The results suggest that SHT is very promising in the treatment of rheumatoid arthritis (RA) by way of its anti-inflammatory and analgesic action. The possible mechanisms for arthritis are multifactorial.


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