A deep-red emission fluorescent probe for detection of viscosity in living cells and mice

2019 ◽  
Vol 11 (20) ◽  
pp. 2626-2629 ◽  
Author(s):  
Shiying Gao ◽  
Yanyan Ma ◽  
Weiying Lin
Keyword(s):  
Fluorescent Probe ◽  
High Stability ◽  
Living Cells ◽  
Living Systems ◽  
Red Emission ◽  
Low Cytotoxicity ◽  
In Cells

A deep-red emission fluorescent probe HY for detecting viscosity in living systems was developed. The probe exhibited ideal properties including good selectivity, high stability and low cytotoxicity. Importantly, the probe HY has been successfully utilized for monitoring viscosity variations in cells and living mice.

A carbonothioate-based far-red fluorescent probe for the specific detection of mercury ions in living cells and zebrafish

The Analyst ◽  
2019 ◽  
Vol 144 (4) ◽  
pp. 1426-1432 ◽  
Author(s):  
Qingxia Duan ◽  
Hanchuang Zhu ◽  
Caiyun Liu ◽  
Ruifang Yuan ◽  
Zhaotong Fang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Water Samples ◽  
Environmental Water ◽  
Living Cells ◽  
Living Systems ◽  
Environmental Water Samples ◽  
Mercury Ions ◽  
Specific Detection

A simple far-red fluorescent probe was developed to monitor mercury ions in environmental water samples and in living systems.

A mitochondria-targeted and deep-red emission ratiometric fluorescent probe for real-time visualization of SO2 in living cells, zebrafish and living mice

The Analyst ◽  
2019 ◽  
Vol 144 (16) ◽  
pp. 4972-4977 ◽  
Author(s):  
Wenjie Gao ◽  
Yanyan Ma ◽  
Weiying Lin
Keyword(s):  
Real Time ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Fast Imaging ◽  
Red Emission ◽  
Real Time Visualization ◽  
Ratiometric Fluorescent Probe

A mitochondria-targeted and red-emissive ratiometric fluorescent probe for fast imaging of SO2 in living cells and zebrafish has been developed, and the changes of SO2 in living mice have been visualized in real time with this probe.

A FRET-based ratiometric two-photon fluorescent probe for superoxide anion detection and imaging in living cells and tissues

The Analyst ◽  
2019 ◽  
Vol 144 (5) ◽  
pp. 1704-1710 ◽  
Author(s):  
Shan Yao ◽  
Chunli Ma ◽  
Yanbing Lu ◽  
Xianzhe Wei ◽  
Xiaowen Feng ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Superoxide Anion ◽  
Living Cells ◽  
Anion Detection ◽  
Two Photon ◽  
Dual Channels ◽  
In Cells

A FRET-based ratiometric two-photon fluorescent probe for superoxide anion detection and imaging in cells and tissue was reported with dual-channels.

A rhodamine-based fluorescent probe for Fe3+: synthesis, theoretical calculation and bioimaging application

2019 ◽  
Vol 11 (19) ◽  
pp. 2565-2570 ◽  
Author(s):  
Zhao Cheng ◽  
Lei Zheng ◽  
Hao Xu ◽  
Long Pang ◽  
Hao He
Keyword(s):  
Theoretical Calculation ◽  
Fluorescent Probe ◽  
Fluorescence Imaging ◽  
Living Cells ◽  
Low Cytotoxicity

A rhodamine-based fluorescent probe J1 with low cytotoxicity and characteristic fluorescence imaging of intracellular Fe3+ in living cells L929.

A dual-site two-photon fluorescent probe for visualizing mitochondrial aminothiols in living cells and mouse liver tissues

2016 ◽  
Vol 40 (9) ◽  
pp. 7399-7406 ◽  
Author(s):  
Fangfang Meng ◽  
Yong Liu ◽  
Xiaoqiang Yu ◽  
Weiying Lin
Keyword(s):  
Fluorescent Probe ◽  
Mouse Liver ◽  
Living Cells ◽  
Living Systems ◽  
Two Photon ◽  
Long Period ◽  
First Time ◽  
Dual Site ◽  
Liver Tissues

In this work, we developed a dual-site two-photon (TP) fluorescent RSH probe (CA-TPP) for imaging mitochondrial RSH in living systems. In particular, probe CA-TPP was capable of using TP fluorescence to track mitochondrial RSH over a long period for the first time.

A red emission fluorescent probe for hydrogen sulfide and its application in living cells imaging

2013 ◽  
Vol 54 (23) ◽  
pp. 2980-2982 ◽  
Author(s):  
Tao Chen ◽  
Yi Zheng ◽  
Zhaochao Xu ◽  
Miao Zhao ◽  
Yongnan Xu ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Red Emission

Ultrafast deep-red emission fluorescent probe for highly selective imaging of endogenous cysteine in living cells and mice

2019 ◽  
Vol 290 ◽  
pp. 581-590 ◽  
Author(s):  
Zhengliang Lu ◽  
Yanan Lu ◽  
Chunhua Fan ◽  
Xin Sun ◽  
Wenqiang Shao ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Red Emission

Tracking mitochondrial viscosity in living systems based on a two-photon and near red probe

2019 ◽  
Vol 43 (43) ◽  
pp. 16945-16949 ◽  
Author(s):  
Min Peng ◽  
Junling Yin ◽  
Weiying Lin
Keyword(s):  
Fluorescence Probe ◽  
Living Cells ◽  
Living Systems ◽  
Red Emission ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence ◽  
Viscosity Changes

A two-photon fluorescence probe, Mito-V, with near-red emission to measure the viscosity changes of mitochondria in living cells and in vivo.

scholarly journals A Phenothiazine-HPQ Based Fluorescent Probe with a Large Stokes Shift for Sensing Biothiols in Living Systems

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2337
Author(s):  
Yan Zheng ◽  
Peng Hou ◽  
Yu Li ◽  
Jingwen Sun ◽  
Hongxia Cui ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Enhancement ◽  
Stokes Shift ◽  
Redox Properties ◽  
Living Systems ◽  
Selective Detection ◽  
Large Stokes Shift ◽  
Low Cytotoxicity ◽  
Mcf 7

Due to the redox properties closely related to numerous physiological and pathological processes, biothiols, including cysteine (Cys), homocysteine (Hcy) and glutathione (GSH), have received considerable attention in biological science. On account of the important physiological roles of these biothiols, it is of profound significance to develop sensitive and selective detection of biothiols to understand their biological profiles. In this work, we reported an efficient fluorescent probe, PHPQ-SH, for detecting biothiols in vitro and vivo, based on the phenothiazine-HPQ skeleton, with DNBS (2,4-dinitrobenzenesulfonate) as the response unit. Probe PHPQ-SH exhibited brilliant sensing performances toward thiols, including a large Stokes shift (138 nm), excellent sensitivity (for GSH, LOD = 18.3 nM), remarkable fluorescence enhancement (163-fold), low cytotoxicity, rapid response (8 min), and extraordinary selectivity. Finally, the probe PHPQ-SH illustrated herein was capable of responding and visualizing biothiols in MCF-7 cells and zebrafish.

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