Polyethyleneimine coated Fe3O4 magnetic nanoparticles induce autophagy, NF-κB and TGF-β signaling pathway activation in HeLa cervical carcinoma cells via reactive oxygen species generation

2020 ◽  
Vol 8 (1) ◽  
pp. 201-211 ◽  
Author(s):  
Shuli Man ◽  
Miao Li ◽  
Jin Zhou ◽  
Haiyue Wang ◽  
Jinyan Zhang ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Magnetic Nanoparticles ◽  
Cancer Cells ◽  
Signaling Pathways ◽  
Signaling Pathway ◽  
Reactive Oxygen Species Generation ◽  
Carcinoma Cells ◽  
Oxygen Species ◽  
Fe3o4 Magnetic Nanoparticles ◽  
Pathway Activation

Fe3O4 magnetic nanoparticles (MNPs) are proved to induce autophagy, NF-κB and TGF-β signaling pathways activation in cancer cells, which is switched on by induced ROS.

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