scholarly journals Broad spectrum antibacterial photodynamic and photothermal therapy achieved with indocyanine green loaded SPIONs under near infrared irradiation

2020 ◽  
Vol 8 (16) ◽  
pp. 4616-4625 ◽  
Author(s):  
K. Bilici ◽  
N. Atac ◽  
A. Muti ◽  
I. Baylam ◽  
O. Dogan ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Indocyanine Green ◽  
Broad Spectrum ◽  
Photothermal Therapy ◽  
Bacterial Infections ◽  
Near Infrared ◽  
Alternative Therapies ◽  
Antimicrobial Photodynamic Therapy ◽  
Infrared Irradiation ◽  
Antibiotic Resistant

Antimicrobial photodynamic therapy (aPDT) and antimicrobial photothermal therapy (aPTT) are promising local and effective alternative therapies for antibiotic resistant bacterial infections and biofilms.

scholarly journals Gold Nanorod-Decorated Metallic MoS2 Nanosheets for Synergistic Photothermal and Photodynamic Antibacterial Therapy

Nanomaterials ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3064
Author(s):  
Sibidou Yougbaré ◽  
Chinmaya Mutalik ◽  
Pei-Feng Chung ◽  
Dyah Ika Krisnawati ◽  
Fajar Rinawati ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Visible Light ◽  
Photothermal Therapy ◽  
Bacterial Infections ◽  
Near Infrared ◽  
Agar Plate ◽  
Solution Temperature ◽  
Photothermal Effect ◽  
Plate Counts ◽  
Molybdenum Disulfide Nanosheets

Light-responsive nanocomposites have become increasingly attractive in the biomedical field for antibacterial applications. Visible-light-activated metallic molybdenum disulfide nanosheets (1T-MoS2 NSs) and plasmonic gold nanorods (AuNRs) with absorption at a wavelength of 808 nm were synthesized. AuNR nanocomposites decorated onto 1T-MoS2 NSs (MoS2@AuNRs) were successfully prepared by electrostatic adsorption for phototherapy applications. Based on the photothermal effect, the solution temperature of the MoS2@AuNR nanocomposites increased from 25 to 66.7 °C after 808 nm near-infrared (NIR) laser irradiation for 10 min. For the photodynamic effect, the MoS2@AuNR nanocomposites generated reactive oxygen species (ROS) under visible light irradiation. Photothermal therapy and photodynamic therapy of MoS2@AuNRs were confirmed against E. coli by agar plate counts. Most importantly, the combination of photothermal therapy and photodynamic therapy from the MoS2@AuNR nanocomposites revealed higher antibacterial activity than photothermal or photodynamic therapy alone. The light-activated MoS2@AuNR nanocomposites exhibited a remarkable synergistic effect of photothermal therapy and photodynamic therapy, which provides an alternative approach to fight bacterial infections.

Evaluation of Antimicrobial Photodynamic Therapy Using Indocyanine Green and Near-Infrared Diode Laser AgainstEnterococcus faecalisin Infected Human Root Canals

2017 ◽  
Vol 35 (5) ◽  
pp. 264-269 ◽  
Author(s):  
Charis Beltes ◽  
Nikolaos Economides ◽  
Hercules Sakkas ◽  
Chrissanthy Papadopoulou ◽  
Theodoros Lambrianidis
Keyword(s):  
Photodynamic Therapy ◽  
Indocyanine Green ◽  
Diode Laser ◽  
Near Infrared ◽  
Antimicrobial Photodynamic Therapy ◽  
Root Canals

Indocyanine green-platinum porphyrins integrated conjugated polymer hybrid nanoparticles for near-infrared-triggered photothermal and two-photon photodynamic therapy

2017 ◽  
Vol 5 (9) ◽  
pp. 1856-1862 ◽  
Author(s):  
Xiao-Hui Wang ◽  
Hong-Shang Peng ◽  
Wei Yang ◽  
Zhao-Di Ren ◽  
Xiao-Ming Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Indocyanine Green ◽  
Conjugated Polymer ◽  
Near Infrared ◽  
Hybrid Nanoparticles ◽  
Infrared Irradiation ◽  
Two Photon ◽  
Polymer Hybrid

Indocyanine green-platinum porphyrins integrated conjugated polymer hybrid nanoparticles for bimodal photothermal and two-photon photodynamic therapy with near-infrared irradiation.

scholarly journals Exploiting cyanine dye J-aggregates/monomer equilibrium in hydrophobic protein pockets for efficient multi-step phototherapy: An innovative concept for smart nanotheranostics

Nanoscale ◽  
2021 ◽  
Author(s):  
Matias Luis Picchio ◽  
Julian Bergueiro Álvarez ◽  
Stefanie Wedepohl ◽  
Roque J Minari ◽  
Cecilia Ines Alvarez Igarzabal ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Contrast Agent ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Cyanine Dye ◽  
Hydrophobic Protein ◽  
Nir Dyes ◽  
Protein Pockets ◽  
J Aggregates ◽  
Innovative Concept

After several decades of development in the field of near-infrared (NIR) dyes for photothermal therapy (PTT), indocyanine green (ICG) still remains the only FDA-approved NIR contrast agent. However, upon NIR...

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