Fabrication of transferrin modified two-photon gold nanoclusters with near-infrared fluorescence and its application for bioimaging

2021 ◽  
Author(s):  
Kangdi He ◽  
Shengrong Yu ◽  
Xiao Wang ◽  
Dian Li ◽  
Jia Chen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Near Infrared ◽  
Gold Nanoclusters ◽  
Living Cells ◽  
Resonance Imaging ◽  
Near Infrared Fluorescence ◽  
Two Photon ◽  
Nir Fluorescence

Transferrin modified AuNCs (Tf-AuNCs) with TP-NIR fluorescence was prepared, and a novel nanoprobe platform Tf-AuNCs@MnO2 was developed for effectively TP-NIR fluorescence and magnetic resonance imaging of living cells and tissues...

scholarly journals Multimodal Mn-doped I–III–VI quantum dots for near infrared fluorescence and magnetic resonance imaging: from synthesis to in vivo application

Nanoscale ◽  
2014 ◽  
Vol 6 (15) ◽  
pp. 9264-9272 ◽  
Author(s):  
Gary Sitbon ◽  
Sophie Bouccara ◽  
Mariana Tasso ◽  
Aurélie Francois ◽  
Lina Bezdetnaya ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Quantum Dots ◽  
Magnetic Resonance ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Resonance Imaging ◽  
Near Infrared Fluorescence ◽  
Nir Fluorescence ◽  
Mn Doped

Cadmium-free quantum dots doped with Mn2+ions show promising results forin vivobimodal MRI and NIR fluorescence imaging.

Near-infrared Fluorescence Optical Imaging in Early Rheumatoid Arthritis: A Comparison to Magnetic Resonance Imaging and Ultrasonography

2015 ◽  
Vol 42 (7) ◽  
pp. 1112-1118 ◽  
Author(s):  
Michaela Krohn ◽  
Sarah Ohrndorf ◽  
Stephanie G. Werner ◽  
Bernd Schicke ◽  
Gerd-Rüdiger Burmester ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Optical Imaging ◽  
Early Rheumatoid Arthritis ◽  
Near Infrared ◽  
Resonance Imaging ◽  
Near Infrared Fluorescence ◽  
Fluorescence Optical Imaging ◽  
Early Ra

Objective.Near-infrared fluorescence optical imaging (FOI) is a novel imaging technology in the detection and evaluation of different arthritides. FOI was validated in comparison to magnetic resonance imaging (MRI), greyscale ultrasonography (GSUS), and power Doppler ultrasonography (PDUS) in patients with early rheumatoid arthritis (RA).Methods.Hands of 31 patients with early RA were examined by FOI, MRI, and US. In each modality, synovitis of the wrist, metacarpophalangeal joints (MCP) 2–5, and proximal interphalangeal joints (PIP) 2–5 were scored on a 4-point scale (0–3). Sensitivity and specificity of FOI were analyzed in comparison to MRI and US as reference methods, differentiating between 3 phases of FOI enhancement (P1–3). Intraclass correlation coefficients (ICC) were calculated to evaluate the agreement of FOI with MRI and US.Results.A total of 279 joints (31 wrists, 124 MCP and 124 PIP joints) were evaluated. With MRI as the reference method, overall sensitivity/specificity of FOI was 0.81/0.00, 0.49/0.84, and 0.86/0.38 for wrist, MCP, and PIP joints, respectively. Under application of PDUS as reference, sensitivity was even higher, while specificity turned out to be low, except for MCP joints (0.88/0.15, 0.81/0.76, and 1.00/0.27, respectively). P2 appears to be the most sensitive FOI phase, while P1 showed the highest specificity. The best agreement of FOI was shown for PDUS, especially with regard to MCP and PIP joints (ICC of 0.57 and 0.53, respectively), while correlation with MRI was slightly lower.Conclusion.FOI remains an interesting diagnostic tool for patients with early RA, although this study revealed limitations concerning the detection of synovitis. Further research is needed to evaluate its full diagnostic potential in rheumatic diseases.

scholarly journals The influence of Gd-DOTA ratios conjugating PLGA-PEG micelles encapsulated IR-1061 in bimodal over–1000 nm near–infrared fluorescence and magnetic resonance imaging

2022 ◽  
Author(s):  
Doan Thi Kim Dung ◽  
Masakazu Umezawa ◽  
Kazunobu Ohnuki ◽  
Karina Nigoghossian ◽  
Kyohei Okubo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Fluorescence Imaging ◽  
Multimodal Imaging ◽  
Near Infrared ◽  
Resonance Imaging ◽  
Biological Objects ◽  
Nir Fluorescence ◽  
Multidimensional Information

Multimodal imaging can provide multidimensional information for understanding concealed microstructures or bioprocesses in biological objects. The combination of over–1000 nm near–infrared (OTN–NIR) fluorescence imaging and magnetic resonance (MR) imaging is...

Novel multifunctional nanospheres of Zn1/3Fe8/3O4@Ag: synthesis, properties and application for multi-modality tumor imaging

2016 ◽  
Vol 4 (40) ◽  
pp. 6510-6515
Author(s):  
Shengping Gao ◽  
Xiaoli Liu ◽  
Chunqiu Zhao ◽  
Meina Su ◽  
Hui Jiang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Near Infrared ◽  
Tumor Imaging ◽  
Resonance Imaging ◽  
Near Infrared Fluorescence ◽  
Nirf Imaging ◽  
Synthesis Properties ◽  
Magnetic Resonance Imaging Mri

New multifunctional nanospheres have been designed and synthesized through a green and facile strategy, which could be readily used in multi-modality tumor imaging through near-infrared fluorescence (NIRF) imaging, magnetic resonance imaging (MRI) and computed tomography (CT) imaging.

Gold nanoclusters decorated with magnetic iron oxide nanoparticles for potential multimodal optical/magnetic resonance imaging

2015 ◽  
Vol 3 (23) ◽  
pp. 5910-5917 ◽  
Author(s):  
Chan Wang ◽  
Yagang Yao ◽  
Qijun Song
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Properties ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Cancer Diagnosis ◽  
Gold Nanoclusters ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Optical And Magnetic Properties

The dual optical and magnetic properties of the synthesized Fe3O4@AuNCs were applicable to cancer diagnosis by fluorescence and MR-based imaging.

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