Recent advances on the pre-oxidation process in electrocatalytic urea oxidation reaction

2022 ◽  
Author(s):  
Wenbin Sun ◽  
Jiechen Li ◽  
Wen Gao ◽  
Luyao Kang ◽  
Fengcai Lei ◽  
...  

The electrocatalytic urea oxidation reaction (UOR) has attracted substantial research interests during the past few years owing to its critical role in coupled electrochemical systems for energy conversion, for example,...

2020 ◽  
Vol 16 (4) ◽  
pp. 454-486 ◽  
Author(s):  
Smita Verma ◽  
Vishnuvardh Ravichandiran ◽  
Nihar Ranjan ◽  
Swaran J.S. Flora

Nitrogen-containing heterocycles are one of the most common structural motifs in approximately 80% of the marketed drugs. Of these, benzimidazoles analogues are known to elicit a wide spectrum of pharmaceutical activities such as anticancer, antibacterial, antiparasitic, antiviral, antifungal as well as chemosensor effect. Based on the benzimidazole core fused heterocyclic compounds, crescent-shaped bisbenzimidazoles were developed which provided an early breakthrough in the sequence-specific DNA recognition. Over the years, a number of functional variations in the bisbenzimidazole core have led to the emergence of their unique properties and established them as versatile ligands against several classes of pathogens. The present review provides an overview of diverse pharmacological activities of the bisbenzimidazole analogues in the past decade with a brief account of its development through the years.


Author(s):  
Nayab Sheikh ◽  
Muhammad Bilal Tahir ◽  
Nisar Fatima ◽  
Muhammad Sagir ◽  
Muhammad Pervaiz ◽  
...  

2021 ◽  
Vol 14 (6) ◽  
pp. 587
Author(s):  
Zhaoyu Chen ◽  
Qinghua Cui ◽  
Michael Caffrey ◽  
Lijun Rong ◽  
Ruikun Du

Hemagglutinin (HA) plays a critical role during influenza virus receptor binding and subsequent membrane fusion process, thus HA has become a promising drug target. For the past several decades, we and other researchers have discovered a series of HA inhibitors mainly targeting its fusion machinery. In this review, we summarize the advances in HA-targeted development of small molecule inhibitors. Moreover, we discuss the structural basis and mode of action of these inhibitors, and speculate upon future directions toward more potent inhibitors of membrane fusion and potential anti-influenza drugs.


Vaccines ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 354
Author(s):  
Chia-Ming Su ◽  
Raymond Robert Richard Rowland ◽  
Dongwan Yoo

Cellular receptors play a critical role in viral infection. At least seven cellular molecules have been identified as putative viral entry mediators for porcine reproductive and respiratory syndrome virus (PRRSV). Accumulating data indicate that among these candidates, CD163, a cysteine-rich scavenger receptor on macrophages, is the major receptor for PRRSV. This review discusses the recent advances and understanding of the entry of PRRSV into cells, viral pathogenesis in CD163 gene-edited swine, and CD163 as a potential target of receptor–ligand for the control of PRRS.


Metals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 274
Author(s):  
Alexander V. Smolin ◽  
Мikhail N. Mikhailov ◽  
Aleksey F. Gadzaov ◽  
Leonid M. Kustov

The problem of identifying correlations between catalytic and electrocatalytic processes is one of the fundamental problems of catalysis among “simple” organic substances, and the oxidation of CO and rCO2 is of great interest, since CO and CO2 are considered in pairs both during catalytic and electrocatalytic transformations. In the case of electrocatalysis, this analysis is important in the study of fuel cells. In this paper, we studied the correlation between the oxidation of reduced forms of CO2 (rCO2) under potentiodynamic-galvanoctatic electrochemical and open-circuit conditions of measurements on polycrystalline (pc)Pt in H2CO3. Periodic oscillations are revealed at the oxidation of Had and rCO2 on (pc)Pt. Quantum chemical calculations were carried out on the Pt13 cluster in order to identify the mechanisms of the rCO2 oxidation reaction. The correspondence in the energy parameters of the oxidation process of rCO2 under open-circuit conditions and electrochemical conditions is shown. The preliminary analysis of the system using density functional (DFT) calculations is carried out and the most stable systems that are based on Pt13 are found, namely rOH-Pt13-(CO)n, rOH-Pt13-(COH) and rOH-Pt13-(rCOOH). OH• species was chosen as the most likely candidate for the role of the oxidant for rCO2. Preliminary calculations for the expected reactions were carried out, and the optimal PES is revealed.


Author(s):  
Yi Xing ◽  
Yiman Xu ◽  
Qilin Wu ◽  
Gang Wang ◽  
Meifang Zhu

This review presents the recent advances of optoelectronic functional fibers in material selection, fabrication, as well as applications in energy conversion, photoelectric sensing, and logical response.


1969 ◽  
Vol 1 (1) ◽  
pp. 90-110 ◽  
Author(s):  
J. Gani

The theory of storage processes, originally formulated by Moran [1] in 1954, has developed in the past fourteen years into a minor subfield of Applied Probability, closely allied to queueing theory. While dam models with discrete inputs are analogous to queueing processes, the essentially continuous nature of water inflows has distinguished generalized storage processes from queues. Indeed, some of the most complex of storage problems have arisen in the case of continuous flows.


2015 ◽  
Vol 44 (11) ◽  
pp. 3418-3430 ◽  
Author(s):  
J. Wencel-Delord ◽  
A. Panossian ◽  
F. R. Leroux ◽  
F. Colobert

Over the past decade the field of the synthesis of axially chiral compounds has been rapidly expanding. Not only key advances have been achieved concerning the already established strategies but also new synthetic routes have been devised. This review showcases the recent developments in this domain.


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