Anti-fatigue effect of Auxis thazard oligopeptide via modulation of AMPK/ PGC-1α pathway in mice

2022 ◽  
Author(s):  
yushan qu ◽  
Hongwu Ji ◽  
wenkui song ◽  
Shuo Peng ◽  
Suhong Zhan ◽  
...  
Keyword(s):  

In this study, the anti-fatigue effect and mechanism of Auxis thazard oligopeptide (ATO) were studied by exhaustive swimming in mice. The results showed that ATO could significantly prolong the exhaustive...

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
DW Lim ◽  
D Lee ◽  
J Sagong ◽  
YT Kim ◽  
MY Kim ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1688
Author(s):  
Ying-Ju Chen ◽  
Chun-Yen Kuo ◽  
Zwe-Ling Kong ◽  
Chin-Ying Lai ◽  
Guan-Wen Chen ◽  
...  

The Taiwan Tilapia is an important aquaculture product in Taiwan. The aquatic by-products generated during Tilapia processing, such as fish bones and skin, are rich in minerals and protein. We aimed to explore the effect of a dietary supplement, comprising a mixture of fermented Tilapia by-products and Monostroma nitidum oligosaccharides as the raw materials, combined with physical training on exercise performance and fatigue. We used a mouse model that displays a phenotype of accelerated aging. Male senescence-accelerated mouse prone-8 (SAMP8) mice were divided into two control groups—with or without physical training—and supplemented with different doses (0.5 times: 412 mg/kg body weight (BW)/day; 1 time: 824 mg/kg BW/day; 2 times: 1648 mg/kg BW/day) of fermented Tilapia by-products and Monostroma nitidum oligosaccharide-containing mixture and combined with exercise training groups. Exercise performance was determined by testing forelimb grip strength and with a weight-bearing exhaustive swimming test. Animals were sacrificed to collect physical fatigue-related biomarkers. Mice dosed at 824 or 1648 mg/kg BW/day showed improvement in their exercise performance (p < 0.05). In terms of biochemical fatigue indicators, supplementation of 824 or 1648 mg/kg BW/day doses of test substances could effectively reduce blood urea nitrogen concentration and lactate concentration and increase the lactate ratio (p < 0.05) and liver glycogen content post-exercise (p < 0.05). Based on the above results, the combination of physical training and consumption of a dietary supplementation mixture of fermented Tilapia by-products and Monostroma nitidum oligosaccharides could improve the exercise performance of mice and help achieve an anti-fatigue effect.


2002 ◽  
Vol 62 (3) ◽  
pp. 453-457 ◽  
Author(s):  
B. M. M. FERNANDES ◽  
A. KOHN ◽  
A. L. SANTOS

Rhipidocotyle pentagonum (Ozaki, 1924) is reported for the first time in South America parasitizing Auxis thazard and in a new host Katsuwonus pelamis. Tergestia laticollis (Rudolphi, 1819) is reported for the first time in South America and in Thunnus albacares, representing a new host record. Copiatestes filiferus (Leuckart, in Sars, 1885) is recorded for the first time in Brazil and in Thunnus albacares, another new host record. Tetrochetus coryphaenae (Yamaguti, 1934) is presented for the first time in Brazil parasitizing Thunnus albacares.


1908 ◽  
Vol 28 ◽  
pp. 615-626
Author(s):  
James G. Gray ◽  
Alexander D. Ross

SUMMARY1. Nickel and the Heusler alloy give “sensitive states” of nearly 2 and about 5 per cent. respectively for a magnetising field of 8 C.G.S. units.2. Steel wire specimens dropped vertically on a stone slab from a height of 1 metre showed a reduction of 37 per cent, in the “sensitive state” for a single fall, 49 per cent, for three falls, 62 per cent, for ten falls, and 73 per cent, for fifty falls.3. After the “sensitive state” has been removed from a specimen by the process of demagnetising by reversals, it cannot be completely restored by reannealing. That is, the specimens exhibit a fatigue effect.4. In the case of one variety of steel, the “sensitive state” had been reduced to less than one-half its original value after seven annealings, and to one-fifth after seventeen.5. No recovery from the fatigue condition was observed in specimens which had been laid aside for fifty-four days.6. Repeated annealings without intermediate magnetic testing showed neither an augmentation of the “sensitive state” nor a fatigue effect.7. Specimens demagnetised at −190° C., heated to room temperature, and cooled again to −190° C., showed a small “sensitive state” at that temperature.8. Larger effects were induced by heating from −190° C. to 15° C., or by cooling from 15° C. to −190° C.9. A “sensitive state” could be induced by any variation of temperature, but not by exposure to a steady temperature, either high or low. The effect is associated solely with change of temperature.10. The amount of “sensitive state” induced by equal temperature alterations varies with the position of the range on the temperature scale and with the material.11. The change from the “sensitive” to the normal condition is unaccompanied by any appreciable change in the specific electrical resistance or elastic constants of the material.


2012 ◽  
Vol 426 (1) ◽  
pp. 142-151 ◽  
Author(s):  
V. Ya. Shur ◽  
A. R. Akhmatkhanov ◽  
I. S. Baturin

2007 ◽  
Vol 40 ◽  
pp. S587
Author(s):  
M. Kasović ◽  
T. Pribanić ◽  
V. Medved

Sign in / Sign up

Export Citation Format

Share Document