Blood Pressure and Ageing; Results of a 15–17 Year Follow-Up Study in South Wales

1973 ◽  
Vol 45 (s1) ◽  
pp. 23s-33s ◽  
Author(s):  
W. E. Miall ◽  
Susan Chinn

1. Several recent studies of the relation between blood pressure and ageing have been re-examined, and it is concluded that none satisfactorily investigates the possibility of separate influences of age and attained pressure in determining the rate of change of pressure with time. 2. If the rate of increase of pressure is proportional to the attained pressure, pressure is an exponential function of age. An attempt has been made to determine the relation of blood pressure with age by fitting curves to individuals' measurements made over periods of 15 1/2 and 17 1/2 years in two epidemiological surveys in South Wales. 3. Three models were used: (1) a linear regression, (2) an exponential function, and (3) a model based on the hypothesis that an individual's pressure fluctuates about a constant mean until a variable age at which it increases at a constant rate. Neither model (2) nor model (3) was significantly better than model (1), but this may have been largely due to the small number of measurements (four) for each subject. 4. A positive slope to the linear regression of pressure on time was obtained for most adults. In middle-aged subjects the distributions of these regression coefficients appear unimodal. The rate of increase was higher in those with initially raised values but increased with age independently of the blood pressure level. In these populations some factor related to ageing appears to play a rôle in causing this increase in pressure in addition to any possible direct influence of the attained pressure.

2018 ◽  
Vol 27 (2) ◽  
pp. 114 ◽  
Author(s):  
Bianca N. I. Eskelson ◽  
Vicente J. Monleon

Forest wildfires consume fuel and are followed by post-fire fuel accumulation. This study examines post-fire surface fuel dynamics over 9 years across a wide range of conditions characteristic of California fires in dry conifer and hardwood forests. We estimated post-fire surface fuel loadings (Mgha−1) from 191 repeatedly measured United States national inventory plots in dry conifer and hardwood stands of 49 California forest wildfires and identified differences across fire severity classes – low, moderate and high. No significant change in duff load was detected within the first 9 years post-fire across all forest types and fire severities. Litter, 1-h and 10-h fuels exhibited a quadratic trend over time in dry conifer stands, peaking ~6 years after fire, whereas hardwood stands displayed a constant rate of increase in those fuel types. For 100- and 1000-h fuels, the annual rate of change was constant for dry conifer and hardwood stands with differing rates of change across fire severity classes. This study was based on an extensive, spatially balanced sample across burned dry conifer and hardwood forests of California. Therefore, the estimated patterns of fuel accumulation are generally applicable to wildfires within this population.


To identify the prevalence of early pathology of cardiovascular diseases, a survey of 400 200 girls) in the age group 15 and 17 years old was conducted as a part of routine medical of the level of blood pressure (BP) was carried out, with the calculation of the average level pressure on the basis of three separate measurements estimated by percentile tables for a registration of a standard resting ECG in 12 leads. According to the results of the survey, into 3 groups: with an increase in blood pressure above 95 ‰ (group 1 – 16 people), which recorded in males (p<0,05); Group 2 (67 people) – adolescents with a normal blood pressure level and group 3 of adolescents with a decrease in blood pressure below 5 ‰ changes in the form of rhythm and conduction disturbances were noted in almost every a predominance of sinus tachycardia in the first group. In the third group of adolescents, form of ectopic rhythm and pacemaker migration were significantly more frequently only 78 % of adolescents were referred for consultation and in-depth examination by a pediatric cardiologist.


Hypertension ◽  
1995 ◽  
Vol 26 (6) ◽  
pp. 1195-1199 ◽  
Author(s):  
José Alfie ◽  
Gabriel D. Waisman ◽  
Carlos R. Galarza ◽  
Marissa I. Magi ◽  
Federico Vasvari ◽  
...  

Hypertension ◽  
2003 ◽  
Vol 42 (4) ◽  
pp. 685-692 ◽  
Author(s):  
Alexandre C. Pereira ◽  
Marcilene S. Floriano ◽  
Glória F.A. Mota ◽  
Roberto S. Cunha ◽  
Fernando L. Herkenhoff ◽  
...  

2020 ◽  
Vol 49 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Shuhei Okazaki ◽  
Haruko Yamamoto ◽  
Lydia D. Foster ◽  
Mayumi Fukuda-Doi ◽  
Masatoshi Koga ◽  
...  

Background: Neurological deterioration (ND) has a major influence on the prognosis of intracerebral hemorrhage (ICH); however, factors associated with ND occurring after 24 h of ICH onset are unknown. Methods: We performed exploratory analyses of data from the Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 trial, which compared intensive and standard blood pressure lowering treatment in ICH. NDs were captured on the adverse event case report form. Logistic regression analysis was performed to examine the independent predictors of late ND. Results: Among 1,000 participants with acute ICH, 82 patients (8.2%) developed early ND (≤24 h), and 64 (6.4%) had late ND. Baseline hematoma volume (adjusted OR [aOR] per 1-cm3 increase 1.04, 95% CI 1.02–1.06, p < 0.0001), hematoma volume increase in 24 h (aOR 2.24, 95% CI 1.23–4.07, p = 0.008), and the presence of intraventricular hemorrhage (IVH; aOR 2.38, 95% CI 1.32–4.29, p = 0.004) were independent predictors of late ND (vs. no late ND). Late ND was a significant risk factor for poor 90-day outcome (OR 3.46, 95% CI 1.82–6.56). No statistically significant difference in the incidence of late ND was noted between the 2 treatment groups. Conclusions: Initial hematoma volume, early hematoma volume expansion, and IVH are independent predictors of late ND after ICH. Intensive reduction in the systolic blood pressure level does not prevent the development of late ND.


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