Computer Simulation of Field Distribution and Excitation of Denervated Muscle Fibers Caused by Surface Electrodes

1999 ◽  
Vol 23 (5) ◽  
pp. 453-456 ◽  
Author(s):  
Martin Reichel ◽  
Winfried Mayr ◽  
Frank Rattay
Keyword(s):  
Computer Simulation ◽  
Field Distribution ◽  
Muscle Fibers ◽  
Denervated Muscle ◽  
Surface Electrodes

scholarly journals Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging

2017 ◽  
Vol 112 ◽  
pp. 84-92 ◽  
Author(s):  
Natalie Pollock ◽  
Caroline A. Staunton ◽  
Aphrodite Vasilaki ◽  
Anne McArdle ◽  
Malcolm J. Jackson
Keyword(s):  
Muscle Fibers ◽  
Denervated Muscle ◽  
Muscle Aging

scholarly journals Two years of Functional Electrical Stimulation by large surface electrodes for denervated muscles improve skin epidermis in SCI

2018 ◽  
Vol 28 (1) ◽  
Author(s):  
Giovanna Albertin ◽  
Helmut Kern ◽  
Christian Hofer ◽  
Diego Guidolin ◽  
Andrea Porzionato ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Functional Electrical Stimulation ◽  
Muscle Fibers ◽  
Cauda Equina ◽  
Skin Thickness ◽  
Surface Electrodes ◽  
Long Term Treatment ◽  
Cord Injury ◽  
Skin Biopsies

Our previous studies have shown that severely atrophic Quadriceps muscles of spinal cord injury (SCI) patients suffering with complete conus and cauda equina lesions, and thus with permanent denervation-induced atrophy and degeneration of muscle fibers, were almost completely rescued to normal size after two years of home-based Functional Electrical Stimulation (h-bFES). Since we used large surface electrodes to stimulate the thigh muscles, we wanted to know if the skin was affected by long-term treatment. Here we report preliminary data of morphometry of skin biopsies harvested from legs of 3 SCI patients before and after two years of h-bFES to determine the total area of epidermis in transverse skin sections. By this approach we support our recently published results obtained randomly measuring skin thickness in the same biopsies after H-E stain. The skin biopsies data of three subjects, taken together, present indeed a statistically significant 30% increase in the area of the epidermis after two years of h-bFES. In conclusion, we confirm a long term positive modulation of electrostimulated epidermis, that correlates with the impressive improvements of the FES-induced muscle strength and bulk, and of the size of the muscle fibers after 2-years of h-bFES.

The Effect of Activity on the Denervated Endplate

1982 ◽  
Vol 40 ◽  
pp. 192-193
Author(s):  
Bruce R. Pachter ◽  
Arthur Eberstein ◽  
Joseph Goodgold
Keyword(s):  
Electrical Stimulation ◽  
Electrical Properties ◽  
Neuromuscular Junction ◽  
Peripheral Nerve ◽  
Healing Process ◽  
Muscle Fibers ◽  
Entire Length ◽  
Denervated Muscle

Following damage to the peripheral nerve, the neuromuscular junction begins to degenerate, the muscle fibers become sensitive to acetylcholine over their entire length, the membrane electrical properties are altered and the muscle fibers become atrophic. It has been proposed that such anomalies might be due to inactivity, a lack of neurotrophic influence or a combination of both factors. The idea that In activity might be responsible for these changes has led to the use of electrotherapy to influence the healing process and promote nerve reinnervation. It has been recently suggested that electrical stimulation might be beneficial in preserving the neuromuscular junction in the denervated muscle. The present study was undertaken to determine morphologically the effect of electrical stimulation treatment on the endplates in denervated muscle.

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