scholarly journals Valorization of rapeseed meal. 3. Effects of glucosinolate content on food intake, weight gain, liver weight and plasma thyroid hormone levels in growing rats

1987 ◽  
Vol 27 (1A) ◽  
pp. 57-66 ◽  
Author(s):  
M. VERMOREL ◽  
Marie-Jeanne DAVICCO ◽  
J. EVRARD ◽  
Y. ANGLARET ◽  
M. GENEST ◽  
...  
Keyword(s):  
Weight Gain ◽  
Thyroid Hormone ◽  
Food Intake ◽  
Liver Weight ◽  
Rapeseed Meal ◽  
Glucosinolate Content ◽  
Hormone Levels ◽  
Growing Rats ◽  
Thyroid Hormone Levels

Long-term effects of thyrotropin-releasing hormone and histidyl-proline diketopiperazine on the maturation of homeothermia and mitochondrial enzyme activities in neonatal rats

1988 ◽  
Vol 119 (4) ◽  
pp. 575-581 ◽  
Author(s):  
Chiaki Miyamori ◽  
Taizo Kato ◽  
Eiichi Imura ◽  
Akisato Murata ◽  
Tamotsu Sato ◽  
...  
Keyword(s):  
Weight Gain ◽  
Thyroid Hormone ◽  
Body Temperature ◽  
Cytochrome C ◽  
Enzyme Activities ◽  
Body Weight Gain ◽  
Neonatal Rats ◽  
Hormone Levels ◽  
Cytochrome C Reductase ◽  
Thyroid Hormone Levels

Abstract. To elucidate the mechanism by which TRH and its metabolite, histidyl-proline diketopiperazine (cyclo(His-Pro)), act on the maturation of homoiothermy, the chronic effects of intrathecal administration of the peptides on body temperature, serum thyroid hormone levels, and mitochondrial energy-producing enzyme activities were examined in neonatal rats. The two peptides or an equimolar mixture of both were injected intrathecally at a dose of 3, 6 and 9 nmol for 7 consecutive days during the 1st, 2nd or 3rd week of life, respectively. Control rats were treated with saline and they were sacrificed at 6 weeks of age. Although food and water intake were not decreased, body weight gain was slightly reduced in the rats treated with TRH or cyclo(His-Pro) during the 1st and 2nd week of life, whereas the mixturetreated rats showed normal weight gain. Body temperature at 25°C was not different in the TRH- and cyclo(HisPro)-treated groups, whereas after cold exposure (5°C for 3 h), the groups treated with TRH during the 1st and 2nd week of life had an impaired thermoregulation at 5 weeks of age. Serum T4 and T3 concentrations were similar in all groups, except in the rats treated with TRH during the 2nd week of life; their thyroid hormone levels were slightly reduced. The TRH treatment suppressed mitochondrial cytochrome c reductase and glucose-6-phosphatase activities, whereas cyclo(His-Pro) reduced cytochrome c reductase and malic enzyme activities. In contrast, α-glycerophosphate dehydrogenase was enhanced by both treatments. These results suggest that TRH and cyclo(His-Pro) modulate the central thermoregulatory mechanism and produce particular changes in the mitochondrial respiratory chains in peripheral thermogenic tissues.

Seasonal changes in weight gain, growth hormone, and thyroid hormones in intact and castrated male moose (Alces alces alces)

1982 ◽  
Vol 60 (11) ◽  
pp. 2941-2946 ◽  
Author(s):  
Morten Ryg
Keyword(s):  
Growth Hormone ◽  
Weight Gain ◽  
Thyroid Hormone ◽  
Food Intake ◽  
Thyroid Hormones ◽  
Seasonal Changes ◽  
Alces Alces ◽  
Serum Concentrations ◽  
Rapid Weight Gain ◽  
Thyroid Hormone Levels

To elucidate possible endocrine mechanisms in the control of cyclic weight gain in moose, serum concentrations of growth hormone (GH), thyroxine (T4), and triiodothyronine (T3) were recorded during the year in two intact and one castrated male moose. Changes in the levels of these hormones were compared with changes in weight gain. Growth hormone often increased to peak values in April or May, but was generally low throughout the period of greatest weight gain. Thyroid hormone levels increased in spring and decreased in autumn, corresponding to onset and cessation of rapid weight gain. Changes in triiodothyronine levels may have been secondary to changes in food intake.

Evaluation of Positive Inotropic Drug Effects on Thyroid Hormone Levels after Open Heart Surgery

2015 ◽  
Vol 16 (2) ◽  
pp. 78
Author(s):  
Umit Kervan ◽  
Anil Ozen ◽  
Utku Unal ◽  
Irfan Tasoglu ◽  
Mahmut Mustafa Ulas ◽  
...  
Keyword(s):  
Drug Therapy ◽  
Thyroid Hormone ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Inotropic Drug ◽  
Hormone Levels ◽  
Inotropic Drugs ◽  
Positive Inotropic Drug ◽  
Thyroid Hormone Levels

<p><b>Objective:</b> The aim of this study was to examine the effects of positive inotropic drugs, including adrenaline, dopamine, and dobutamine on thyroid hormone levels following open heart surgery.</p><p><b>Methods:</b> We analyzed free thyroid hormones (FT3 and FT4) and thyroid-stimulating hormones (TSH) in 200 consecutive patients undergoing open heart surgery. Patients were divided into 5 groups according to the inotropic drug administration as follows: Group A (n = 46) received dopamine alone; Group B (n = 40), dopamine and dobutamine; Group C (n = 36), dopamine, dobutamine, and adrenaline; Group D (n = 32), adrenaline alone; and Group E (n = 46), placebo. Procedural factors affecting thyroid hormones were recorded and included cardiopulmonary bypass (CPB) time, cross-clamping time, degree of hypothermia, and the duration and doses of positive inotropic drugs. Blood samples for hormone assays were collected before initiation of inotropic drug therapy (baseline) and postoperatively at 24, 72, and 120 hours after drug therapy.</p><p><b>Results:</b> FT3, FT4, and TSH levels at baseline were similar in all groups. Although there was a trend showing very slight increases in thyroid hormone levels from baseline to the 24th, 72nd, and 120th postoperative hours after drug therapy, these changes were not significant, and there were also no significant differences between the groups. There was also no significant statistical difference in CPB time, cross-clamping time, degree of hypothermia, and duration and doses of positive inotropic drugs between groups.</p><p><b>Conclusion:</b> Although thyroid hormone levels were affected by positive inotropic drug usage after open heart surgery, this effect was not significant and thyroid hormone levels remained within normal ranges.</p>

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