scholarly journals Prominent seasonality of 25(OH)D vitamin deficiency in Latvia: Age and gender-related variations and testing regimen

2022 ◽  
Vol 131 ◽  
pp. 02004
Author(s):  
Sergey Nikulshin ◽  
Jana Osite ◽  
Stella Lapina ◽  
Anda Krisane ◽  
Iveta Dzivite-Krisane ◽  
...  
Keyword(s):  
High Latitude ◽  
Social Impact ◽  
Age Groups ◽  
Central Laboratory ◽  
Cross Sectional ◽  
Age And Gender ◽  
Younger Age ◽  
Optimal Period ◽  
And Gender ◽  
Sectional Analysis

Seasonality of 25(OH)D deficiency rate is a factor of major clinical and social impact and should be considered when planning for appropriate testing and tailored correction. We present retrospective cross-sectional analysis of over a million 25(OH)D tests performed in two leading Latvian laboratories – Central Laboratory and E.Gulbja Laboratory. Both series of tests demonstrated prominent seasonal variability of 25(OH)D deficiency rate (<20 ng/ml) and critical deficiency rate (<12 ng/ml): the lowest percentage of deficient tests was in August, while a significant peak was found in March-April. This trend was present at all ages and in both genders, variations were pronounced even for a high-latitude country and more prominent for critical deficiency, in younger age groups and in males. Analysis of testing regimens of both laboratories revealed that schedule was not optimal, period of higher testing intensity being far removed from the 25(OH)D deficiency peak.

scholarly journals Correlation between bone turnover and metabolic markers with age and gender: a cross-sectional study of hospital information system data

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Ju Shao ◽  
Shao-Song Zhou ◽  
Yuan Qu ◽  
Bi-Bo Liang ◽  
Qing-Hong Yu ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Clinical Research ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Hospital Data ◽  
Medication History ◽  
Cross Sectional ◽  
Age And Gender ◽  
And Gender

Abstract Background Bone turnover and metabolic indicators are related to age and gender. Age and gender should be matched in subjects in disease control research of bone turnover and metabolism, but strict matching of gender and age increases the difficulty and cost of the research. Therefore, the aim of this study was to solve it is necessary to strictly match age and gender in clinical research in bone metabolism. Methods A cross-sectional study was conducted from the data were extracted from the HIS of ZhuJiang Hospital. Data relating to seven bone turnover and metabolic indicators from 1036 patients between January 2018 and October 2019 were analyzed. Results P1NP, β-CTx and 25(OH)D were significant different in individuals younger than 20 years of age. ALP was significantly higher in those under 20 years of age and lower at age 20–39 compared with other age groups. The concentrations of Ca and P were different among the groups aged 0–19, 20–39, and 40–59 years of age groups but exhibited no difference above 60 years of age. PTH expression was not dependent on age. P1NP, β-CTx and PTH concentrations were not significantly different between the genders within the same age group. ALP was significantly different between genders within the age range 20–59 years. Ca and 25(OH)D were significantly different between the genders for those older than 60. Serum P was significantly different in the two genders for those aged 40–79. Patients received both alfacalcidol and calcium treatment differently from the others in P1NP, β-CTx, Serum Ca, P and ALP. Conclusion P1NP and β-CTx were highly correlated with age. If these two indictors require analysis in a case control study, the patients and controls should be strictly matched by age under 20 years. The demarcation point for ALP was 40 years of age. Ca and P were strongly recommended strict matching according to age in disease research. The difference in P1NP, β-CTx, 25(OH)D and ALP between genders depends on age differences. Medication history should be considered in bone turnover and metabolic clinical research.

scholarly journals Correlation between bone turnover and metabolic markers with age and gender: a cross-sectional study of hospital information system data

2020 ◽  
Author(s):  
Shao Ju ◽  
Shaosong Zhou ◽  
Yuan Qu ◽  
bibo liang ◽  
Qing-Hong Yu ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Age And Gender ◽  
Metabolic Markers ◽  
The Difference ◽  
Highly Correlated ◽  
And Gender

Abstract Background: Bone turnover and metabolic indicators are related to age and gender. Age and gender should be matched in subjects in disease control research of bone turnover and metabolism, but strict matching of gender and age increases the difficulty and cost of the research. Therefore, the aim of this study was to solve the question of whether it is necessary to strictly match age and gender in clinical research in bone metabolism.METHODS: Patient data were extracted from the HIS of ZhuJiang Hospital, Southern Medical University. From these data, a cross-sectional study was conducted. Data relating to seven bone turnover and metabolic indicators from 1036 patients between January 2018 and October 2019 were analyzed. A total of 156 patients aged under 20 were identified and analyzed separately. RESULTS: P1NP, β-CTx and 25(OH)D were significant different in individuals younger than 20 years of age. ALP was significantly higher in those under 20 years of age and lower at age 20-39 compared with other age groups. The concentrations of Ca and P were different among the groups aged 0-19, 20-39, and 40-59 years of age groups but exhibited no difference above 60 years of age. PTH expression was not dependent on age. P1NP, β-CTx and PTH concentrations were not significantly different between the genders within the same age group. ALP was significantly different between genders within the age range 20-59 years. Ca and 25(OH)D were significantly different between the genders for those older than 60. Serum P was significantly different in the two genders for those aged 40-79. CONCLUSION: P1NP and β-CTx were highly correlated with age. If these two indictors require analysis in a case control study, the patients and controls should be strictly matched by age under 20 years. The demarcation point for ALP was 40 years of age. Ca and P were strongly recommended strict matching according to age in disease research. The difference in P1NP, β-CTx, 25(OH)D and ALP between genders depends on age differences.

The Swedish Version of the Temperament and Character Inventory (TCI)

2008 ◽  
Vol 24 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Sven Brändström ◽  
Sören Sigvardsson ◽  
Per-Olof Nylander ◽  
Jörg Richter
Keyword(s):  
Personality Assessment ◽  
Age Groups ◽  
Temperament And Character Inventory ◽  
Swedish Version ◽  
Age And Gender ◽  
Younger Age ◽  
Character Inventory ◽  
And Gender ◽  
Independent Effects ◽  
The Impact

Abstract. In order to establish new norms of the Swedish version of the Temperament and Character Inventory (TCI), data from 2,209 Swedish individuals (age between 13 and 80) was analyzed. The second aim was to evaluate the impact of age and gender on the questionnaire scores. The third aim was to investigate whether the TCI can be meaningfully applied to adolescents in personality assessment as a basis for further research and clinical studies. Age and gender showed independent effects on personality dimensions, which implies that age and gender specific norms have to be established for the TCI. Furthermore, the results in terms of inconsistencies in the correlational and factorial structure, as well as low internal consistency scores in the younger age groups, suggest that the adult version of the TCI should not be applied below the age of 17; for these age groups we recommend the use of the junior TCI (JTCI). The inventory is under further development and several items are in need of revision in order to create less complicated formulations, enabling an improvement in the psychometrics.

scholarly journals Correlation between bone turnover and metabolic markers with age and gender: a cross-sectional study of hospital information system data

2020 ◽  
Author(s):  
Shao Ju ◽  
Shaosong Zhou ◽  
Yuan Qu ◽  
Bibo Liang ◽  
Qing-Hong Yu ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Clinical Research ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Hospital Data ◽  
Medication History ◽  
Cross Sectional ◽  
Age And Gender ◽  
And Gender

Abstract Background: Bone turnover and metabolic indicators are related to age and gender. Age and gender should be matched in subjects in disease control research of bone turnover and metabolism, but strict matching of gender and age increases the difficulty and cost of the research. Therefore, the aim of this study was to solve it is necessary to strictly match age and gender in clinical research in bone metabolism.METHODS: A cross-sectional study was conducted from the data were extracted from the HIS of ZhuJiang Hospital. Data relating to seven bone turnover and metabolic indicators from 1036 patients between January 2018 and October 2019 were analyzed.RESULTS: P1NP, β-CTx and 25(OH)D were significant different in individuals younger than 20 years of age. ALP was significantly higher in those under 20 years of age and lower at age 20-39 compared with other age groups. The concentrations of Ca and P were different among the groups aged 0-19, 20-39, and 40-59 years of age groups but exhibited no difference above 60 years of age. PTH expression was not dependent on age. P1NP, β-CTx and PTH concentrations were not significantly different between the genders within the same age group. ALP was significantly different between genders within the age range 20-59 years. Ca and 25(OH)D were significantly different between the genders for those older than 60. Serum P was significantly different in the two genders for those aged 40-79. Patients received both alfacalcidol and calcium treatment differently from the others in P1NP, β-CTx, Serum Ca, P and ALP.CONCLUSION: P1NP and β-CTx were highly correlated with age. If these two indictors require analysis in a case control study, the patients and controls should be strictly matched by age under 20 years. The demarcation point for ALP was 40 years of age. Ca and P were strongly recommended strict matching according to age in disease research. The difference in P1NP, β-CTx, 25(OH)D and ALP between genders depends on age differences. Medication history should be considered in bone turnover and metabolic clinical research.

Hand Force of Men and Women Over 65 Years of Age as Measured by Maximum Pinch and Grip Force

2008 ◽  
Vol 16 (1) ◽  
pp. 24-41 ◽  
Author(s):  
Caroline W. Stegink Jansen ◽  
Bruce R. Niebuhr ◽  
Daniel J. Coussirat ◽  
Dana Hawthorne ◽  
Laura Moreno ◽  
...  
Keyword(s):  
Grip Force ◽  
Force Measurement ◽  
Age Groups ◽  
Normative Values ◽  
Cross Sectional ◽  
Age And Gender ◽  
Pinch Force ◽  
Hand Force ◽  
And Gender ◽  
The Impact

This cross-sectional study aimed to assess the impact of age and gender on 4 measures of grip and pinch force of well elderly community dwellers and to provide normative values. The hypotheses were that age and gender affect pinch and grip force and that these 2 factors might interact. Hand strength of 224 seniors 65–92 years old was tested. Grip and pinch force decreased in successively older age groups past 65 years. Men’s grip force exceeded that of women in all age groups. Men’s hand-force decline was steeper than that of women over successive age groups, suggesting that gender differences in force decreased with age. Trends were the same for all 4 types of grip- and pinch-force measurement but were most clearly visible in grip and key-pinch force. Norms were provided for seniors age 65–85+ years in 5-yr increments.

scholarly journals The Who and When of Worry: The Fading Impact of Gender on Worry and Anxiety Severity Among Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 372-372
Author(s):  
Katie Granier ◽  
Rebecca Ingram ◽  
Daniel Segal
Keyword(s):  
Older Adults ◽  
Interaction Effect ◽  
Significant Interaction ◽  
Age Groups ◽  
Significant Interaction Effect ◽  
Age And Gender ◽  
Younger Women ◽  
Younger Age ◽  
Younger Men ◽  
And Gender

Abstract Introduction. This study examined the influence of age and gender on diverse worry constructs and overall anxiety among younger (age 18-30) and older (age 65+) adults. Methods. 411 participants (311 younger, 100 older adults; 77.1% female) completed the PSWQ, BMWS, WDQ, and GAS online. Results. Among a series of 2x2 between-subjects ANOVAs, significant interaction effects between age and gender were found among all worry and anxiety measures. Specifically, there was a significant interaction effect on worry severity as measured by the PSWQ (F[1, 393]=4.28, p&lt;.05), the WDQ (F[1, 397]=8.42, p&lt;.01) and the BMWS (F[1, 396]=10.41, p&lt;.01). Gender had a larger impact on worry among younger adults than older, though both age groups showed similar patterns of women reporting greater worry than men. Though both younger and older adults showed a gender difference in worry severity, this difference was mitigated by late life. There was also an interaction effect on anxiety (GAS total) in that younger women reported greater anxiety than younger men but older adults reported similar anxiety across genders, F(1, 384)=9.78, p&lt;.01. Simple main effects analysis showed that younger women scored higher than older women on all measures of worry and anxiety, whereas younger men scored higher than older men on the PSWQ and WDQ but not the BMWS or GAS. Discussion. Consistent with previous literature, women reported greater worry and anxiety than men. However, this difference was mitigated and even extinguished among some measures in older adults. Possible explanations are discussed.

scholarly journals Prevalence of refractive errors by age and gender in patients reporting to ophthalmology department.

2020 ◽  
Vol 27 (09) ◽  
pp. 1989-1994
Author(s):  
Adeel Ahmed Siddiqui ◽  
Muhammad Ajmal Chaudhary ◽  
Muhammad Zafar Ullah ◽  
Majid Hussain ◽  
Nadeem Ahmed ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
P Value ◽  
Refractive Errors ◽  
Care Hospital ◽  
Age Group ◽  
Ocular Surgery ◽  
Cross Sectional ◽  
Age And Gender ◽  
And Gender

Objectives: To determine the age and gender specific prevalence of different refractive errors in the patients presenting to the Ophthalmology Departments of the tertiary care hospital. Study Design: Analytical Cross-sectional study. Setting: Departments of Outpatient Ophthalmology at THQ Hospital Kabirwala, The Children’s Hospital & The Institute of Child Health Multan and Nishtar Hospital, Multan. Period: January 2020 to May 2020. Material & Methods: A total of 400 patients ≥ 4 years age of either gender were included. Patients with history of ocular surgery, trauma and advanced fundus disease were excluded. Age and gender of the patients was noted. Clinical examination and autorefraction were carried out. Quantitative data is presented as mean ± SD and qualitative data as frequency and percentages. Chi-square test is used to assess the association of refractive errors with age groups and gender. Results: Median age of the participants was 20 years (range 04 – 92 years). Males constituted 58% (n = 232) of the study participants. Most common refractive error were astigmatism (n=298, 74.5%) and myopia in 187 (46.75%) patients. Prevalence of myopia was significantly higher (p-value < 0.001) in 11-20 (39.6%) and 21-40 (34.2%) years age group and in males (64.7%, p-value 0.01). Hypermetropia was significantly higher (p-value <0.001) in 4-10 (36.8%) and ≥ 41 (38.7%) years age group with no gender predilection. Conclusion: This study shows prevalence of myopia being highest in males age 11-40 years and prevalence of hypermetropia being highest in children between 4-10 year and elderly ≥ 41 year with no gender predilection.

Sign in / Sign up

Export Citation Format

Share Document