scholarly journals Incidence of intramammary infections during the dry period without or with antibiotic treatment in dairy cows – a quantitative analysis of published data

2006 ◽  
Vol 37 (1) ◽  
pp. 25-48 ◽  
Author(s):  
Aurélie Robert ◽  
Henri Seegers ◽  
Nathalie Bareille
Keyword(s):  
Quantitative Analysis ◽  
Dairy Cows ◽  
Antibiotic Treatment ◽  
Published Data ◽  
Dry Period ◽  
Intramammary Infections

scholarly journals Comparative efficacy of antimicrobial treatments in dairy cows at dry-off to prevent new intramammary infections during the dry period or clinical mastitis during early lactation: a systematic review and network meta-analysis

2019 ◽  
Vol 20 (2) ◽  
pp. 199-216 ◽  
Author(s):  
C. B. Winder ◽  
J. M. Sargeant ◽  
D. Hu ◽  
C. Wang ◽  
D. F. Kelton ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dairy Cows ◽  
Meta Analysis ◽  
Clinical Mastitis ◽  
Comparative Efficacy ◽  
Dry Period ◽  
Quality Of Reporting ◽  
Intramammary Infections ◽  
Antimicrobial Treatments

AbstractA systematic review and network meta-analysis were conducted to assess the relative efficacy of antimicrobial therapy given to dairy cows at dry-off. Eligible studies were controlled trials assessing the use of antimicrobials compared to no treatment or an alternative treatment, and assessed one or more of the following outcomes: incidence of intramammary infection (IMI) at calving, incidence of IMI during the first 30 days in milk (DIM), or incidence of clinical mastitis during the first 30 DIM. Databases and conference proceedings were searched for relevant articles. The potential for bias was assessed using the Cochrane Risk of Bias 2.0 algorithm. From 3480 initially identified records, 45 trials had data extracted for one or more outcomes. Network meta-analysis was conducted for IMI at calving. The use of cephalosporins, cloxacillin, or penicillin with aminoglycoside significantly reduced the risk of new IMI at calving compared to non-treated controls (cephalosporins, RR = 0.37, 95% CI 0.23–0.65; cloxacillin, RR = 0.55, 95% CI 0.38–0.79; penicillin with aminoglycoside, RR = 0.42, 95% CI 0.26–0.72). Synthesis revealed challenges with a comparability of outcomes, replication of interventions, definitions of outcomes, and quality of reporting. The use of reporting guidelines, replication among interventions, and standardization of outcome definitions would increase the utility of primary research in this area.

Non-antimicrobial approaches at drying-off for treating and preventing intramammary infections in dairy cows. Part 1. Meta-analyses of efficacy of using an internal teat sealant without a concomitant antimicrobial treatment

2019 ◽  
Vol 20 (1) ◽  
pp. 86-97 ◽  
Author(s):  
Simon Dufour ◽  
Vincent Wellemans ◽  
Jean-Philippe Roy ◽  
Pierre Lacasse ◽  
Alfredo Ordonez-Iturriaga ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Antimicrobial Treatment ◽  
Dry Period ◽  
Intramammary Infections ◽  
Current Review ◽  
Bismuth Subnitrate ◽  
Reduce Risk ◽  
High Level ◽  
Meta Analyses ◽  
Better Than

AbstractUse of antimicrobial approaches at drying-off for preventing new intramammary infections (IMI) during the dry period in dairy cows could be replaced by non-antimicrobial approaches. Such approaches would be of interest not only for organic but also for conventional dairy producers. The objective of the current review was to quantify the effect of non-antimicrobial internal teat sealant (ITS)-based approaches at drying-off for treating and preventing IMI, when compared with no treatment or with an antimicrobial-based approach. The protocol for this review was published before initiating the review. A total of 18 trials from 16 articles could be used to investigate the effect of an ITS-based approach. With the available results, we conclude with a high level of confidence that non-antimicrobial ITS-based dry-off approaches are efficient for preventing new IMI during the dry period when compared with no treatment, and would reduce risk of new IMI by 52%. Moreover, we are relatively confident that a bismuth subnitrate-based ITS performed better than an antimicrobial for preventing new IMI during the dry period (a risk reduction of 23%). Similarly, we are relatively confident that an ITS-based approach would only slightly or not at all reduce the prevalence of IMI at calving compared with untreated quarters.

scholarly journals Risk factors for new intramammary infections during the dry period in untreated dairy cows from herds using selective dry cow therapy

animal ◽  
2008 ◽  
Vol 2 (2) ◽  
pp. 247-254 ◽  
Author(s):  
A. Robert ◽  
P. Roussel ◽  
N. Bareille ◽  
D. Ribaud ◽  
F. Sérieys ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dairy Cows ◽  
Dry Period ◽  
Intramammary Infections ◽  
Dry Cow Therapy

scholarly journals Dry Period or Early Lactation—Time of Onset and Associated Risk Factors for Intramammary Infections in Dairy Cows

Pathogens ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 224
Author(s):  
Julia Nitz ◽  
Nicole Wente ◽  
Yanchao Zhang ◽  
Doris Klocke ◽  
Martin tho Seeth ◽  
...  
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Dairy Cows ◽  
Body Condition ◽  
Clinical Mastitis ◽  
Early Lactation ◽  
Dry Period ◽  
Intramammary Infections ◽  
Environmental Pathogens ◽  
Associated Risk Factors

The aim of this study was to define the time-related period of intramammary infections and its relation to risk factors for intramammary infections and clinical mastitis at cow and quarter levels. In total, 269 German Holstein Frisian dairy cows on three farms in Northern and Eastern Germany were included in this study. Quarter milk samples were collected at dry-off, 3 ± 1 days after calving and 17 ± 3 days after calving, for cytomicrobiological examination. Risk factors at quarter- and cow-level associated with intramammary infections and clinical mastitis were recorded during the trial period. Data were analyzed using logistic regression procedures and odds ratios were calculated. Calving for the second time increased the odds of clinical mastitis during the first 100 days of lactation compared to cows calving for the third time or more. A high milk yield after calving was a risk factor for new infections, with environmental pathogens 17 ± 3 days postpartum. A body condition score after calving less than 3.5 was associated with a decreased risk of having an intra-mammary infection (IMI) with non-aureus staphylococci and coryneforms 3 ± 1 days postpartum and consistent body condition between dry-off and early lactation decreased the risk of intramammary infections after calving. The absence of a ring of hyperkeratosis at the teat apex shown at dry-off was associated with a lower risk of intramammary infections with environmental pathogens 17 ± 3 days postpartum. This study shows the important influence of the dry period and early lactation on intramammary infections and clinical mastitis postpartum in dairy cows. Udder quarters may have eliminated pathogens during the dry period in 43.6% of cases in this study. Additionally, new infections occurred during early lactation, so 5.1% more quarters were infected 17 ± 3 days compared to 3 ± 1 days postpartum. New infections can be traced to non-aureus staphylococci and Staphylococcus aureus from dry-off up until 3 ± 1 days postpartum, and to non-aureus staphylococci, Staphylococcus aureus and Streptococcus uberis, after calving. In total, 88.7% of the infected quarters showed new infections with another pathogen species 3 ± 1 days postpartum than at dry-off, and 89.2% of the quarters 17 ± 3 days postpartum than 3 ± 1 days postpartum. In conclusion, the early lactation has just as important an influence on intramammary infections postpartum in dairy cows as the dry period. There is the possibility that udder quarters eliminate pathogens during the early lactation, especially during the dry period. However, there is also the danger that new infections manifest, with a large proportion of new infections occurring after calving. Thus, additional control strategies are of great importance to prevent new infections occurring during early lactation as well as during the dry period to reduce negative effects on milk yield and culling hazards in dairy cows by minimizing the associated risk factors.

Effects of dry period length on milk yield and content and metabolic status of high-producing dairy cows under heat stress

2021 ◽  
Vol 53 (2) ◽  
Author(s):  
A. Boustan ◽  
V. Vahedi ◽  
M. Abdi Farab ◽  
H. Karami ◽  
R. Seyedsharifi ◽  
...  
Keyword(s):  
Heat Stress ◽  
Dairy Cows ◽  
Milk Yield ◽  
Period Length ◽  
Metabolic Status ◽  
Dry Period

scholarly journals MicroRNA profiles of dry secretions through the first three weeks of the dry period from Holstein cows

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Ellie J. Putz ◽  
Austin M. Putz ◽  
Hyeongseon Jeon ◽  
John D. Lippolis ◽  
Hao Ma ◽  
...  
Keyword(s):  
Regression Models ◽  
Transition Period ◽  
Mirna Profile ◽  
Random Regression ◽  
Q Value ◽  
Dry Period ◽  
Regulate Gene Expression ◽  
Intramammary Infections ◽  
Non Coding Rnas ◽  
Insight Into

AbstractIn dairy cows, the period from the end of lactation through the dry period and into the transition period, requires vast physiological and immunological changes critical to mammary health. The dry period is important to the success of the next lactation and intramammary infections during the dry period will adversely alter mammary function, health and milk production for the subsequent lactation. MicroRNAs (miRNAs) are small non-coding RNAs that can post transcriptionally regulate gene expression. We sought to characterize the miRNA profile in dry secretions from the last day of lactation to 3, 10, and 21 days post dry-off. We identified 816 known and 80 novel miRNAs. We found 46 miRNAs whose expression significantly changed (q-value < 0.05) over the first three weeks of dry-off. Additionally, we examined the slopes of random regression models of log transformed normalized counts and cross analyzed the 46 significantly upregulated and downregulated miRNAs. These miRNAs were found to be associated with important components of pregnancy, lactation, as well as inflammation and disease. Detailing the miRNA profile of dry secretions through the dry-off period provides insight into the biology at work, possible means of regulation, components of resistance and/or susceptibility, and outlets for targeted therapy development.

scholarly journals Effect of increasing digestible undegraded protein supply to dairy cows in late gestation on the yield and composition of milk during the subsequent lactation

1996 ◽  
Vol 63 (2) ◽  
pp. 201-213 ◽  
Author(s):  
J. M. Moorby ◽  
R. J. Dewhurst ◽  
S. Marsden
Keyword(s):  
Dairy Cows ◽  
Milk Protein ◽  
Barley Straw ◽  
Protein Supplement ◽  
Dry Period ◽  
Body Protein ◽  
Grass Silage ◽  
Management Regime ◽  
Protein Pool ◽  
Ad Libitum

AbstractEffects of feeding a protein supplement to dairy cows during the dry period on performance during the following lactation were investigated in two experiments. Holstein-Friesian cows were paired towards the end of lactation, and, after drying off, one of each pair received a typical dry cow management regime of ad libitum grass silage (experiment 1), or a mix of grass silage and distillers' grains or pressed beet pulp (experiment 2). The other cows were offered restricted access to the same basal diet, together with ad libitum access to barley straw and 0·5 kg/day high protein maize gluten meal. During the following lactation, animals from both groups were treated without reference to dry period treatment, and were offered equal access to the same lactation diet. Data were analysed by analysis of variance of experiment means and by parallel curve analysis using sample means. In experiment 1, milk yields were similar (27·2 v. 27·9 (s.e.d. 2·12) kg/day for control and supplemented animals respectively) but milk protein yields, and hence concentrations, were significantly higher (P < 0·001) from supplemented animals (28·9 v. 31·8 (s.e.d. 0·58) g/kg). In experiment 2, milk yields were significantly higher (P < 0·001) from supplemented animals (mean 33·3 v. 35·4 (s.e.d. 1·66) kg/day; however, milk protein yields were also significantly increased (P < 0·001) and the change in milk protein concentration was small. No difference in dry-matter intake was recorded in a subset of animals during early lactation in experiment 2. It is hypothesized that the maternal labile body protein pool was maintained or replenished during the dry period by the provision of the protein supplement, and that this had a significant effect on subsequent lactation performance.

Effects of 2 intramammary antimicrobial formulations on control of mastitis during the dry-period and performance of dairy cows

2021 ◽  
Vol 37 (5) ◽  
pp. 635-640
Author(s):  
Ahmadreza Mirzaei ◽  
Elizabeth A. Cox ◽  
Scott T. Kieser ◽  
Barbara Petersen ◽  
Todd R. Bilby ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Dry Period ◽  
And Performance

scholarly journals CD49f+ mammary epithelial cells decrease in milk from dairy cows stressed by overstocking during the dry period

2017 ◽  
Vol 84 (4) ◽  
pp. 414-417 ◽  
Author(s):  
Mario Baratta ◽  
Silvia Miretti ◽  
Paolo Accornero ◽  
Giovanna Galeati ◽  
Andrea Formigoni ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Dairy Cows ◽  
Differential Expression ◽  
Mammary Epithelial Cells ◽  
Stocking Density ◽  
Mammary Epithelial ◽  
Early Lactation ◽  
Dry Period ◽  
Cytokeratin 18 ◽  
Cell Subpopulations

The work reported in this Research Communication describes the modification in epithelial cell populations during the first and the last month of milking in Holstein Friesian cows that have undergone different management during the dry period, and we report the differential expression of CD49f+ and cytokeratin18+ cell subpopulations. Twenty six cows were randomly divided into 2 balanced groups that were housed at stocking density of either 11 m2 (CTR) or 5 m2 from 21 ± 3 d before the expected calving until calving. Cells collected from milk samples taken in early lactation and late lactation were directly analysed for CD45, CD49f, cytokeratin 14, cytokeratin 18 and cell viability. We observed a differential expression with a significant reduction in CD49f+ (P < 0·01) and cytokeratin 18+ (P < 0·05) cells in early lactation. Differences were still evident in late lactation but were not significant. These observations suggest that mammary epithelial cell immunophenotypes could be associated with different animal management in the dry period and we hypothesise they may have a role as biomarkers for mammary gland function in dairy cows.

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