Dectection of early thrombus formation in LVAD by accoustic fast fourier transformation (FFT) analysis. A novel approach for monitoring

2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
P. von Samson-Himmelstjerna ◽  
A. Meyer ◽  
T. Müller ◽  
N. Zießnitz ◽  
J. Garbade ◽  
...  
2011 ◽  
Vol 27 (5) ◽  
pp. S284 ◽  
Author(s):  
D. Une ◽  
G. Chikazawa ◽  
R. Karkhanis ◽  
J. Vincent ◽  
J. Sever ◽  
...  

2018 ◽  
Vol 141 (1) ◽  
Author(s):  
Arash Nayebzadeh ◽  
Hanieh Tabkhi ◽  
Yoav Peles

Hydrodynamic cavitation downstream a range of micropillar geometries entrenched in a microchannel were studied experimentally. Pressurized helium gas at the inlet tank and vacuum pressure at the outlet propelled distilled water through the device and trigger cavitation. The entire process from cavitation inception to the development of elongated attached cavity was recorded. Three modes of cavitation inception were observed and key parameters of cavitation processes, such as cavity length and angle of attachment, were compared among various micropillar geometries. Cavitation downstream of a triangular micropillar was found to have a distinct inception mode with relatively high cavitation inception numbers. After reaching its full elongated form, it prevailed through a larger system pressures and possessed the longest attached cavity. Cavity angle of attachments was predominantly related to the shape of the micropillar. Micropillars with sharp vertex led to lower cavity attachment angles close to the flow separation point, while circular micropillars resulted in higher angles. Twin circular micropillars have a unique cavitation pattern that was affected by vortex shedding. Fast Fourier transformation (FFT) analysis of the cavity image intensity revealed transverse cavity shedding frequencies in various geometries and provided an estimation for vortex shedding frequencies.


Author(s):  
Takahiro Okabe ◽  
Naoki Katagata ◽  
Toshihiro Sakaki ◽  
Takao Inamura ◽  
Koji Fumoto

This paper describes the investigation of the effect of a prefilmer edge thickness on the breakup phenomena of aliquid film in a prefilmer airblast atomizer. The breakup phenomena of the liquid film at five prefilmer edge thicknesses (160, 500, 1250, 2000, and 3000 μm) under various conditions was observed using a high-speed camera. The breakup length of the liquid film was calculated by an image processing technique developed in this study. In order to quantitatively evaluate the effect of the prefilmer edge thickness on the breakup frequency, the Fast Fourier Transformation (FFT) analysis was conducted based on the time evolution of the breakup length. The results indicated that the breakup length increase and the breakup frequency decreases by increasing prefilmer edge thickness due to a larger volume of a liquid accumulation attaching to the prefilmer edge. The FFT analysis showed that the increase in prefilmer edge thickness causes the transition of the maximal power spectrum to a lower frequency (i.e. less than 100 Hz) due to the increase in the liquid accumulation at the edge as well. Finally, adimensionless correlation has been proposed for the breakup length of a liquid film.DOI: http://dx.doi.org/10.4995/ILASS2017.2017.4931 


Electronics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 192
Author(s):  
Umer Sadiq Khan ◽  
Xingjun Zhang ◽  
Yuanqi Su

The active contour model is a comprehensive research technique used for salient object detection. Most active contour models of saliency detection are developed in the context of natural scenes, and their role with synthetic and medical images is not well investigated. Existing active contour models perform efficiently in many complexities but facing challenges on synthetic and medical images due to the limited time like, precise automatic fitted contour and expensive initialization computational cost. Our intention is detecting automatic boundary of the object without re-initialization which further in evolution drive to extract salient object. For this, we propose a simple novel derivative of a numerical solution scheme, using fast Fourier transformation (FFT) in active contour (Snake) differential equations that has two major enhancements, namely it completely avoids the approximation of expansive spatial derivatives finite differences, and the regularization scheme can be generally extended more. Second, FFT is significantly faster compared to the traditional solution in spatial domain. Finally, this model practiced Fourier-force function to fit curves naturally and extract salient objects from the background. Compared with the state-of-the-art methods, the proposed method achieves at least a 3% increase of accuracy on three diverse set of images. Moreover, it runs very fast, and the average running time of the proposed methods is about one twelfth of the baseline.


Author(s):  
Yousun Li

In the time domain simulation of the response of an offshore structure under random waves, the time histories of the wave field should be generated as the input to the dynamic equations. Herein the wave field is the wave surface elevation, the water particle velocities and accelerations at structural members. The generated time histories should be able to match the given wave-field spectral descriptions, to trace the structural member motions if it is a compliant offshore structure, and be numerically efficient. Most frequently used generation methods are the direct summation of a limited number of cosine functions, the Fast Fourier Transformation, and the digital filtering model. However, none of them can really satisfy all the above requirements. A novel technique, called the Modulated Discrete Fourier Transformation, has been developed. Under this method, the wave time histories at each time instant is a summation of a few time-varying complex functions. The simulated time histories have continuous spectral density functions, and the motions of the structural members are well included. This method seems to be superior to all the conventional methods in terms of the above mentioned three requirements.


Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Ulrich Herken ◽  
Weilun Quan

Purpose: Amplitude spectrum area (AMSA), which is calculated from the ventricular fibrillation (VF) waveform using fast Fourier transformation, has been recognized as a predictor of successful defibrillation (DF) and as an index of myocardial perfusion and viability during resuscitation. In this study, we investigated whether a change in AMSA occurring during CPR would predict DF outcome for subsequent DF attempts after a failed DF. We hypothesized that a patient responding to CPR with an increase in AMSA would have an increased likelihood of DF success. Methods: This was a retrospective analysis of out-of-hospital cardiac arrest patients who received a second DF due to initially shock-resistant VF. A total of 193 patients with an unsuccessful first DF were identified in a manufacturer database of electrocardiographic defibrillator records. AMSA was calculated for the first DF (AMSA1) and the second DF (AMSA2) during a 2.1 sec window ending 0.5 sec prior to DF. A successful DF attempt was defined as the presence of an organized rhythm with a rate ≥ 40 / min starting within 60 sec from the DF and lasting for > 30 sec. After the failed first DF, all patients received CPR for 2 to 3 minutes before delivery of the second DF. Change in AMSA (dAMSA) was calculated as dAMSA = AMSA2 - AMSA1. Results: The overall second DF success rate was 14.5%. Multivariable logistic regression showed that both AMSA1 and dAMSA were independent predictors of second DF success with odds ratios of 1.24 (95% CI 1.12 - 1.38, p<0.001) and 1.27 (95% CI 1.16 - 1.41, p<0.001) for each mVHz change in AMSA or dAMSA, respectively. Conclusions: In initially DF-resistant VF, a high initial AMSA value predicted an increased likelihood of second shock success. An increase of AMSA in response to CPR also predicted a higher second shock success rate. Monitoring of AMSA during resuscitation therefore may be useful to guide CPR efforts, possibly including timing of second shock delivery. These findings also further support the value of AMSA as indicator of myocardial viability.


2015 ◽  
Vol 113 (06) ◽  
pp. 1312-1322 ◽  
Author(s):  
Sofia Nordling ◽  
Jaan Hong ◽  
Karin Fromell ◽  
Fredrik Edin ◽  
Johan Brännström ◽  
...  

SummaryIschaemia-reperfusion injury (IRI) poses a major challenge in many thrombotic conditions and in whole organ transplantation. Activation of the endothelial cells and shedding of the protective vascular glycocalyx during IRI increase the risk of innate immune activation, cell infiltration and severe thrombus formation, promoting damage to the tissue. Here, we present a novel one-step strategy to protect the vasculature by immobilisation of a unique multi-arm heparin conjugate to the endothelium. Applying a new in vitro blood endothelial cell chamber model, the heparin conjugate was found to bind not only to primary human endothelial cells but also directly to the collagen to which the cells adhered. Incubation of hypoxic endothelial cells with freshly drawn human blood in the blood chambers elicited coagulation activation reflected by thrombin anti-thrombin formation and binding of platelets and neutrophils. Immobilisation of the heparin conjugate to the hypoxic endothelial cells created a protective coating, leading to a significant reduction of the recruitment of blood cells and coagulation activation compared to untreated hypoxic endothelial cells. This novel approach of immobilising multi-arm heparin conjugates on the endothelial cells and collagen of the basement membrane ensures to protect the endothelium against IRI in thrombotic disorders and in transplantation.


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