Copper-Catalyzed Decarboxylative N-Arylation of Indole-2-carboxylic Acids
Keyword(s):
A novel decarboxylative N-arylation of indole-2-carboxylic acids with aryl halides is developed. The reaction proceeds efficiently in the presence of Cu2O as the catalyst to give the corresponding N-aryl indoles in high yields. This synthetic method shows good functional group tolerance and offers an alternative route to construct N-aryl indoles.
Keyword(s):
Keyword(s):
Keyword(s):
2018 ◽
Keyword(s):
2018 ◽
Vol 21
(4)
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pp. 298-301
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