scholarly journals Proceduralist Given Sedation is Safe and Feasible in Pediatric Flexible Bronchoscopy

2019 ◽  
Vol 08 (04) ◽  
pp. 214-217 ◽  
Author(s):  
Javeed Iqbal Bhat ◽  
Bashir A. Charoo ◽  
Zubair Mushtaq Tramboo ◽  
Shihab Zahoor
Keyword(s):  
Standard Deviation ◽  
Side Effects ◽  
Flexible Bronchoscopy ◽  
Interquartile Range ◽  
Procedural Sedation ◽  
The Mean

AbstractThe objective of this research was to study the effectiveness and safety of proceduralist given sedation in pediatric flexible bronchoscopy. Flexible bronchoscopy was performed in all 267 patients. All patients received midazolam and/or ketamine. The median (interquartile range [IQR]) age of the studied population was 16 (18) months. The indication of bronchoscopy varied. The mean ± standard deviation (SD) dose of midazolam was 0.109 (0.03) mg/kg and that of ketamine was 1.17 (0.43) mg/kg. We observed minor side effects of procedural sedation. All patients underwent procedure successfully. Flexible bronchoscopy in children can be safely performed under sedation using a combination of midazolam and ketamine.

scholarly journals Blunt and Penetrating Liver Trauma have Similar Outcomes in the Modern Era

2020 ◽  
pp. 145749692092164
Author(s):  
A. A. Keizer ◽  
J. H. C. Arkenbosch ◽  
V. Y. Kong ◽  
R. Hoencamp ◽  
J. L. Bruce ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Injury Severity ◽  
Mortality Rates ◽  
Liver Trauma ◽  
Interquartile Range ◽  
Shock Index ◽  
Hepatic Trauma ◽  
Revised Trauma Score ◽  
The Mean ◽  
Trauma Score

Background: The trend in liver trauma management has progressively become increasingly conservative. However, a vast majority of literature focuses heavily on the management of blunt trauma. This study reviews the management of hepatic trauma at a major trauma center in a developing world setting, in order to compare blunt and penetrating liver trauma and to define current management algorithms and protocols. Methods: All patients who sustained liver trauma between 2012 to 2018 were identified in the Hybrid Electronic Medical Registry and extracted for further analysis. Results: A total of 808 patients with hepatic trauma were managed by our trauma center. There were 658 males and 150 females. The mean age was 30 years (standard deviation 13.3). A total of 68 patients died (8.2%) and a total of 290 (35%) patients required intensive care unit admission. The mean presenting shock index was 0.806 (standard deviation 0.67–1.0), the median Injury Severity Score was 18 (interquartile range 10–25) and the mean Revised Trauma Score was 12 (standard deviation 11–12). There were 367 penetrating and 441 blunt liver injuries. The age distribution was similar in both groups. There were significantly less females in the penetrating group. The shock index and the Injury Severity Score on presentation were significantly worse in the blunt group, respectively: 0.891 (standard deviation 0.31) versus 0.845 (standard deviation 0.69) (p < 0.001) and score 21 (interquartile range 13–27) versus 16 (interquartile range 9–20) (p < 0.01). The opposite applied to the Revised Trauma Score of 11.75 (standard deviation 0.74) versus 11.19 (standard deviation 1.3) (p < 0.001). There were significantly more associated intra-abdominal injuries in the penetrating group than the blunt group, in particular that of hollow organs, and 84% of patients with a penetrating injury underwent a laparotomy while only 33% of the blunt injuries underwent a laparotomy. The mortality rate was comparable between both groups. Conclusion: Hepatic trauma is still associated with a high morbidity rate, although there have been dramatic improvements in mortality rates over the last three decades. The mortality rates for blunt and penetrating liver trauma are now similar. Non-operative management is feasible for over two-thirds of blunt injuries and for just under 20% of penetrating injuries.

scholarly journals PERBANDINGAN EFEKTIVITAS BERKUMUR MENGGUNAKAN LARUTAN PROPOLIS LEBAH 12,38% (APIS MELLIFERA) DAN KLORHEKSIDIN GLUKONAT 0,2 % TERHADAP INDEKS PLAK

2014 ◽  
Vol 2 (1) ◽  
pp. 46-55
Author(s):  
Dara Puspita Harvi ◽  
Nur Indrawati Lipoeto ◽  
Hidayati Hidayati
Keyword(s):  
Apis Mellifera ◽  
Standard Deviation ◽  
Side Effects ◽  
Dental Plaque ◽  
Chlorhexidine Gluconate ◽  
Plaque Index ◽  
P Value ◽  
Significant Difference ◽  
The Mean ◽  
Dental Plaque Index

Dental plaque is the primary etiologic in the development of caries and periodontal disease. Chlorhexidine gluconate 0.2% is the mouthwash that is widely used and effective in reducing dental plaque index, but this mouthwash is chemical with few side effects if used for long periods. Propolis is a bee product that has a high content of flavonoids antibacterial and has many benefits in health and has minimal side effects because it belongs to natural product. This study aims to determine differences in the gargling effectiveness using Chlorhexidine gluconate 0.2% and bee propolis solution 12.38% (Apis mellifera) in reducing dental plaque index. The method used in this research was a clinical experimental with the design of one group pretest and posttest. The subjects consisted of 20 students of MA DR. Abd. Ahmad PGAI Padang. Dental plaque index was measured using PHP plaque index before and after gargling using the solution of bee propolis (Apis mellifera) 12.38% and chlorhexidine gluconate 0.2%. The data of research findings were analyzed using paired T-test (p<0.05). The results show that the mean of plaque index reduction of gargling using the solution of bee propolis 12.38% (Apis mellifera) is 0,88 with the standard deviation of ± 0.66 and the mean of plaque index of gargling using Chlorhexidine gluconate 0. 2% is 1.56 with the standard deviation of ± 0.79. There is a significant difference with p value = 0.005 (p <0.05). Chlorhexidine gluconate 0.2% shows higher reduction, but this mouthwash is the chemical with few side effects, while the solution of bee propolis 12.38% (Apis mellifera) is a natural substance that is safer to use.

Use of Trimmed Duplicates Derived from Laboratory Data To Estimate Standard Deviation

1994 ◽  
Vol 77 (6) ◽  
pp. 1660-1663
Author(s):  
Richard L Johnson ◽  
George W Latimer ◽  
Cliff Spiegelman
Keyword(s):  
Standard Deviation ◽  
Normal Distribution ◽  
Laboratory Data ◽  
Interquartile Range ◽  
Mean Absolute Deviation ◽  
Robust Estimators ◽  
Absolute Deviation ◽  
Mean Squared Errors ◽  
The Mean ◽  
Estimate Standard Deviation

Abstract Improved standard deviation estimates from possibly biased duplicate measurements can be derived from appropriately trimmed plots of standard deviation estimates using pairs of replicates vs the quantiles of a half-normal distribution. Simulated studies show that these estimates exhibit generally lower mean-squared errors and biases than do more standard robust estimators of location—¾ times the interquartile range and 3/2 times the mean absolute deviation from the median.

Summarizing data

2020 ◽  
pp. 211-242
Author(s):  
Janet L. Peacock ◽  
Philip J. Peacock
Keyword(s):  
Standard Deviation ◽  
Categorical Data ◽  
Worked Examples ◽  
Interquartile Range ◽  
Different Types ◽  
The Mean

This chapter describes types of quantitative and categorical data and shows how these different types of data can be summarized numerically and in graphs. It gives worked examples of how to calculate the mean, median, standard deviation, and interquartile range, and gives examples of displaying data in graphs.

At Least One Standard Deviation Above the Mean

1969 ◽  
Vol 14 (9) ◽  
pp. 470-471
Author(s):  
M. DAVID MERRILL
Keyword(s):  
Standard Deviation ◽  
The Mean

The Estimation of Blood Platelet Survival

1972 ◽  
Vol 28 (03) ◽  
pp. 447-456 ◽  
Author(s):  
E. A Murphy ◽  
M. E Francis ◽  
J. F Mustard
Keyword(s):  
Standard Deviation ◽  
Least Squares ◽  
Experimental Error ◽  
Blood Platelet ◽  
Least Squares Estimation ◽  
Systematic Relationship ◽  
Platelet Survival ◽  
The Mean ◽  
Normally Distributed

SummaryThe characteristics of experimental error in measurement of platelet radioactivity have been explored by blind replicate determinations on specimens taken on several days on each of three Walker hounds.Analysis suggests that it is not unreasonable to suppose that error for each sample is normally distributed ; and while there is evidence that the variance is heterogeneous, no systematic relationship has been discovered between the mean and the standard deviation of the determinations on individual samples. Thus, since it would be impracticable for investigators to do replicate determinations as a routine, no improvement over simple unweighted least squares estimation on untransformed data suggests itself.

PENGARUH PENDIDIKAN KESEHATAN REPRODUKSI PADA PEER GROUP (TEMAN SEBAYA) TERHADAP PENGETAHUAN DAN PERSEPSI REMAJA TENTANG PENDEWASAAN USIA PERKAWINAN DI SMA NEGERI 1 KECAMATAN NAMORAMBE KAB. DELI SERDANG 2018

2020 ◽  
Vol 1 (2) ◽  
pp. 56-66
Author(s):  
Irma Linda
Keyword(s):  
Standard Deviation ◽  
Health Education ◽  
Reproductive Health ◽  
Peer Group ◽  
Peer Groups ◽  
A Value ◽  
Significant Difference ◽  
Reproductive Health Education ◽  
The Mean ◽  
Adolescent Perceptions

Background: Early marriages are at high risk of marital failure, poor family quality, young pregnancies at risk of maternal death, and the risk of being mentally ill to foster marriage and be responsible parents. Objective: To determine the effect of reproductive health education on peer groups (peers) on the knowledge and perceptions of adolescents about marriage age maturity. Method: This research uses the Quasi experimental method with One group pre and post test design, conducted from May to September 2018. The statistical analysis used in this study is a paired T test with a confidence level of 95% (α = 0, 05). Results: There is an average difference in the mean value of adolescent knowledge between the first and second measurements is 0.50 with a standard deviation of 1.922. The mean difference in mean scores of adolescent perceptions between the first and second measurements was 4.42 with a standard deviation of 9.611. Conclusion: There is a significant difference between adolescent knowledge on the pretest and posttest measurements with a value of P = 0.002, and there is a significant difference between adolescent perceptions on the pretest and posttest measurements with a value of p = 0.001. Increasing the number of facilities and facilities related to reproductive health education by peer groups (peers) in adolescents is carried out on an ongoing basis at school, in collaboration with local health workers as prevention of risky pregnancy.

Regularity and latency of units in ventral cochlear nucleus: implications for unit classification and generation of response properties

1988 ◽  
Vol 60 (1) ◽  
pp. 1-29 ◽  
Author(s):  
E. D. Young ◽  
J. M. Robert ◽  
W. P. Shofner
Keyword(s):  
Standard Deviation ◽  
Cochlear Nucleus ◽  
Interspike Interval ◽  
Rate Adaptation ◽  
Stellate Cells ◽  
Instantaneous Rate ◽  
Ventral Cochlear Nucleus ◽  
Bushy Cell ◽  
Low Pass ◽  
The Mean

1. The responses of neurons in the ventral cochlear nucleus (VCN) of decerebrate cats are described with regard to their regularity of discharge and latency. Regularity is measured by estimating the mean and standard deviation of interspike intervals as a function of time during responses to short tone bursts (25 ms). This method extends the usual interspike-interval analysis based on interval histograms by allowing the study of temporal changes in regularity during transient responses. The coefficient of variation (CV), equal to the ratio of standard deviation to mean interspike interval, is used as a measure of irregularity. Latency is measured as the mean and standard deviation of the latency of the first spike in response to short tone bursts, with 1.6-ms rise times. 2. The regularity and latency properties of the usual PST histogram response types are shown. Five major PST response type classes are used: chopper, primary-like, onset, onset-C, and unusual. The presence of a prepotential in a unit's action potentials is also noted; a prepotential implies that the unit is recorded from a bushy cell. 3. Units with chopper PST histograms give the most regular discharge. Three varieties of choppers are found. Chop-S units (regular choppers) have CVs less than 0.35 that are approximately constant during the response; chop-S units show no adaptation of instantaneous rate, as measured by the inverse of the mean interspike interval. Chop-T units have CVs greater than 0.35, show an increase in irregularity during the response and show substantial rate adaptation. Chop-U units have CVs greater than 0.35, show a decrease in irregularity during the response, and show a variety of rate adaptation behaviors, including negative adaptation (an increase in rate during a short-tone response). Irregular choppers (chop-T and chop-U units) rarely have CVs greater than 0.5. Choppers have the longest latencies of VCN units; all three groups have mean latencies at least 1 ms longer than the shortest auditory nerve (AN) fiber mean latencies. 4. Chopper units are recorded from stellate cells in VCN (35, 42). Our results for chopper units suggest a model for stellate cells in which a regularly firing action potential generator is driven by the summation of the AN inputs to the cell, where the summation is low-pass filtered by the membrane capacitance of the cell.(ABSTRACT TRUNCATED AT 400 WORDS)

scholarly journals Blood Oxygenation Level Dependent Magnetic Resonance Imaging (MRI), Dynamic Contrast Enhanced MRI and Diffusion Weighted MRI for Benign and Malignant Breast Cancer Discrimination: A Preliminary Experience

Cancers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 2421
Author(s):  
Roberta Fusco ◽  
Vincenza Granata ◽  
Mauro Mattace Raso ◽  
Paolo Vallone ◽  
Alessandro Pasquale De Rosa ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Univariate Analysis ◽  
Mean Value ◽  
Blood Oxygenation ◽  
Breast Lesions ◽  
Dce Mri ◽  
Malignant Lesions ◽  
The Mean ◽  
And Diffusion ◽  
Skewness And Kurtosis

Purpose. To combine blood oxygenation level dependent magnetic resonance imaging (BOLD-MRI), dynamic contrast enhanced MRI (DCE-MRI), and diffusion weighted MRI (DW-MRI) in differentiation of benign and malignant breast lesions. Methods. Thirty-seven breast lesions (11 benign and 21 malignant lesions) pathologically proven were included in this retrospective preliminary study. Pharmaco-kinetic parameters including Ktrans, kep, ve, and vp were extracted by DCE-MRI; BOLD parameters were estimated by basal signal S0 and the relaxation rate R2*; and diffusion and perfusion parameters were derived by DW-MRI (pseudo-diffusion coefficient (Dp), perfusion fraction (fp), and tissue diffusivity (Dt)). The correlation coefficient, Wilcoxon-Mann-Whitney U-test, and receiver operating characteristic (ROC) analysis were calculated and area under the ROC curve (AUC) was obtained. Moreover, pattern recognition approaches (linear discrimination analysis and decision tree) with balancing technique and leave one out cross validation approach were considered. Results. R2* and D had a significant negative correlation (−0.57). The mean value, standard deviation, Skewness and Kurtosis values of R2* did not show a statistical significance between benign and malignant lesions (p > 0.05) confirmed by the ‘poor’ diagnostic value of ROC analysis. For DW-MRI derived parameters, the univariate analysis, standard deviation of D, Skewness and Kurtosis values of D* had a significant result to discriminate benign and malignant lesions and the best result at the univariate analysis in the discrimination of benign and malignant lesions was obtained by the Skewness of D* with an AUC of 82.9% (p-value = 0.02). Significant results for the mean value of Ktrans, mean value, standard deviation value and Skewness of kep, mean value, Skewness and Kurtosis of ve were obtained and the best AUC among DCE-MRI extracted parameters was reached by the mean value of kep and was equal to 80.0%. The best diagnostic performance in the discrimination of benign and malignant lesions was obtained at the multivariate analysis considering the DCE-MRI parameters alone with an AUC = 0.91 when the balancing technique was considered. Conclusions. Our results suggest that the combined use of DCE-MRI, DW-MRI and/or BOLD-MRI does not provide a dramatic improvement compared to the use of DCE-MRI features alone, in the classification of breast lesions. However, an interesting result was the negative correlation between R2* and D.

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