scholarly journals Effect of Autogenous Cortical Bone Grafting in Conjunction with Guided Tissue Regeneration in the Treatment of Intraosseous Periodontal Defects

2010 ◽  
Vol 04 (04) ◽  
pp. 403-411 ◽  
Author(s):  
Gonca Cayir Keles ◽  
Mahmut Sumer ◽  
Burcu Ozkan Cetinkaya ◽  
Ferda Tutkun ◽  
S. Burcak Simsek
Keyword(s):  
Clinical Trial ◽  
Cortical Bone ◽  
Tissue Regeneration ◽  
Chronic Periodontitis ◽  
Bone Grafting ◽  
Alveolar Bone ◽  
Additional Benefit ◽  
Guided Tissue Regeneration ◽  
Treatment Modalities ◽  
Combined Approach

Objectives: The aim of this clinical trial was to evaluate the additional benefit of using guided tissue regeneration (GTR) with autogenous cortical bone (ACB) grafting versus ACB grafting alone for the regenerative treatment of intraosseous periodontal defects.Methods: Via a split-mouth design, 12 patients with chronic periodontitis (five men, seven women; mean age, 45.3±4.6 years) who had probing pocket depths (PPDs) of ≥6 mm following initial periodontal therapy were randomly assigned to two treatments in contralateral areas of the dentition: a combination of ACB grafting and GTR (with a absorbable membrane of polylactic acid) or ACB grafting alone. The compared parameters were preoperative and 6-month postoperative PPDs, clinical attachment levels (CALs), and radiographic alveolar bone heights.Results: Both treatment modalities resulted in significant changes in the postoperative measurements from the preoperative values (P<.01). The reduction in the PPDs, gain in the CALs, and gain in the radiographic alveolar bone heights were 4.58±1.08, 4.25±1.06, and 5.50±2.24 mm in the patients treated with ACB grafting and GTR and 4.92±1.00, 4.50±0.80, and 5.92±1.83 mm in those treated with ACB grafting alone, respectively. The differences between the treatments were not statistically significant (P>.05).Conclusions: Within the study limitations, both ACB grafting with GTR and ACB grafting alone lead to significant improvements in clinical and radiographic parameters at 6 months postoperatively. The combined approach does not provide any additional benefit for treating intraosseous periodontal defects. (Eur J Dent 2010;4:403-411)

scholarly journals In Vitro and In Vivo Studies of Hydrophilic Electrospun PLA95/β-TCP Membranes for Guided Tissue Regeneration (GTR) Applications

Nanomaterials ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 599 ◽  
Author(s):  
Chien-Chung Chen ◽  
Sheng-Yang Lee ◽  
Nai-Chia Teng ◽  
Hsin-Tai Hu ◽  
Pei-Chi Huang ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Animal Study ◽  
Tissue Regeneration ◽  
Alveolar Bone ◽  
Guided Tissue Regeneration ◽  
In Vivo Studies ◽  
Defect Sites ◽  
Significant Difference ◽  
Bone Height

The guided tissue regeneration (GTR) membrane is a barrier intended to maintain a space for alveolar bone and periodontal ligament tissue regeneration but prevent the migration of fast-growing soft tissue into the defect sites. This study evaluated the physical properties, in vivo animal study, and clinical efficacy of hydrophilic PLA95/β-TCP GTR membranes prepared by electrospinning (ES). The morphology and cytotoxicity of ES PLA95/β-TCP membranes were evaluated by SEM and 3-(4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) respectively. The cementum and bone height were measured by an animal study at 8 and 16 weeks after surgery. Fifteen periodontal patients were selected for the clinical trial by using a commercial product and the ES PLA95/β-TCP membrane. Radiographs and various indexes were measured six months before and after surgery. The average fiber diameter for this ES PLA95/β-TCP membrane was 2.37 ± 0.86 µm. The MTT result for the ES PLA95/β-TCP membrane showed negative for cytotoxicity. The significant differences in the cementum and bone height were observed between empty control and the ES PLA95/β-TCP membrane in the animal model (p < 0.05). Clinical trial results showed clinical attachment level (CAL) of both control and ES PLA95/β-TCP groups, with a significant difference from the pre-surgery results after six months. This study demonstrated that the ES PLA95/β-TCP membrane can be used as an alternative GTR membrane for clinical applications.

scholarly journals Observation on the Effect of Bone Grafting Alone and Guided Tissue Regeneration Combined with Bone Grafting to Repair Periodontal Intraosseous Defects

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Yongping Yuan ◽  
Jiajia Zhao ◽  
Nv He
Keyword(s):  
Bone Density ◽  
Bone Defect ◽  
Tissue Regeneration ◽  
Bone Grafting ◽  
Alveolar Bone ◽  
Guided Tissue Regeneration ◽  
Control Group ◽  
Observation Group ◽  
Aesthetic Appearance ◽  
The Aesthetic

Objective. To investigate the curative effect of guided tissue regeneration (GTR) combined with bone grafting and improve the aesthetic appearance of patients’ gingiva. Methods. A total of 86 patients with periodontal intraosseous defects were selected from February 2019 to February 2021. All the patients were divided into a control group and an observation group according to the random number table, with 43 patients in each group. Bone grafting was performed in the control group, while GTR was additionally used in the observation group on the basis of the control group. The surgical data and follow-up data were collected and organized. The alveolar bone mineral density, the change in the height of the bone defect, plaque index (PLI), sulcus hemorrhage index (SBI), PD, gingival recession (GR), clinical attachment loss (CAL), and other relevant data of the two groups in 6 months before and after surgery were compared. Six months after surgery, the cosmetic morphology of the patient's gums in the soft tissues around her teeth was evaluated. Results. Six months after surgery, the alveolar bone density of patients in two groups increased compared with that before surgery, and the height of the bone defect decreased compared with that before surgery. The alveolar bone density of the observation group was higher than that of the control group, and the height of the bone defect was lower than that of the control group ( P < 0.05 ). Six months after surgery, the PLI, SBI, PD, and CAL of patients in both groups were lower than those before surgery, while the GR was higher than that before surgery. PD and CAL values in the observation group were lower than those in the control group, and GR was higher than that in the control group ( P < 0.05 ). Six months after surgery, there was no significant difference in PLI and SBI scores between the two groups ( P < 0.05 ). Six months after surgery, the gingival cosmetic scores of the two groups of patients were higher than those before surgery. The observation group was higher than the control group ( P < 0.05 ). Conclusion. GTR combined with bone grafting has a good effect in the repair of periodontal intraosseous defects and can effectively promote the reconstruction and recovery of periodontal intraosseous defects in patients. At the same time, it can significantly improve the aesthetic appearance of patients’ gums, with good clinical application value.

Premaxillary Osteotomy and Guided Tissue Regeneration in Secondary Bone Grafting in Children with Bilateral Cleft Lip and Palate

2007 ◽  
Vol 44 (5) ◽  
pp. 469-475 ◽  
Author(s):  
Julia K. Scott ◽  
Roger M. Webb ◽  
Timothy R. Flood
Keyword(s):  
Tissue Regeneration ◽  
Bone Grafting ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Alveolar Bone ◽  
Guided Tissue Regeneration ◽  
Mixed Dentition ◽  
Collagen Membrane ◽  
Alveolar Bone Grafting ◽  
Secondary Alveolar Bone Grafting

Objective: To introduce a surgical technique for secondary alveolar bone grafting performed in conjunction with premaxillary osteotomy and guided tissue regeneration in children with bilateral clefts. This paper also looks at the outcomes of this surgery in a series of 15 consecutive patients. Methods: Secondary alveolar bone grafting (with a premaxillary osteotomy and guided tissue regeneration with a collagen membrane) is usually carried out in the mixed dentition stage. This retrospective study used patients’ medical records, radiographs, and clinical examination to assess the outcome of the surgery. Patients were followed up for an average of 3 years. Results: Bone grafting was successful in all cases. No premaxillae were lost and there was no long-term morbidity of the donor site. Radiographic assessment of the bone heights showed an average of 94% retention, 3 months postoperatively. Preliminary assessment of maxillary canine eruption is encouraging, with 79% being fully erupted in those patients who are at least 3 years post–bone grafting. Conclusion: Premaxillary osteotomy allows repositioning of the premaxilla to its optimal preplanned position and successful closure of all fistulae. We have found that use of a collagen membrane is a useful adjunct.

scholarly journals Role of sea buckthorn oil in management of chronic periodontitis: follow-up study

2016 ◽  
Vol 4 (2) ◽  
pp. 33 ◽  
Author(s):  
Anamika Sharma ◽  
Shatakshi Sharma ◽  
Shivi Khattri ◽  
Harshita Garg
Keyword(s):  
Chronic Periodontitis ◽  
Periodontal Ligament ◽  
Alveolar Bone ◽  
Sea Buckthorn ◽  
Long Term Results ◽  
Treatment Modalities ◽  
Adjunctive Treatment ◽  
Scaling And Root Planing ◽  
Root Planing ◽  
Sea Buckthorn Oil

Periodontitis is an inflammatory condition resulting in loss of periodontal ligament and alveolar bone. Nonsurgical therapy remains the cornerstone of periodontal treatment. For sustained plaque control it plays an important role in achieving successful long-term results for the care of Chronic Periodontitis subjects. Proper maintenance and patient hygiene plays a vital role in suppression of re-colonization of micro-organism. Many adjunctive treatment modalities along with mechanical debridement have been clinically used and investigated for their efficacy. Systemic antioxidants in conjunction with scaling and root planing can offer additional effects and can be used as an adjunctive treatment. Patients with periodontal disease display increased PMN number and activity, resulting in high degree of free radical release culminating in heightened oxidative damage to gingival tissues, periodontal ligament and alveolar bone. Damage mediated by free radicals can be mitigated by "antioxidant defense system ".Sea buckthorn oil is an omega-7 fatty acid antioxidant which has unique botanical and nutritional properties thereby benefiting mucous membrane by reducing inflammation, improving wound healing and showing excellent antibacterial property. In this research patients were prescribed systemic antioxidant after the phase 1 therapy ie scaling and root planing to observe its effects on the various clinical parameters.

scholarly journals COMPARATIVE CHARACTERISTICS OF VARIOUS TYPES OF MEMBRANES USED FOR BONE GRAFTING AND GUIDED TISSUE REGENERATION IN DENTISTRY AND MAXILLOFACIAL SURGERY

2017 ◽  
Vol 21 (5) ◽  
pp. 291-296
Author(s):  
I. Mecuku ◽  
A. A Muraev ◽  
Julia V. Gazhva ◽  
S. G Ivashkevich
Keyword(s):  
Bone Defect ◽  
Tissue Regeneration ◽  
Bone Grafting ◽  
Maxillofacial Surgery ◽  
Guided Tissue Regeneration ◽  
Dental Practice ◽  
Risk Of Infection ◽  
Professional Literature ◽  
Surgical Wounds ◽  
High Degree

This review aims to analyze the domestic and foreign professional literature, and it shows the main positive and negative properties of the materials for the manufacture of membranes used in modern dental practice in bone-grafting interventions and guided tissue regeneration. Emphasis is placed on the importance of developing a new individual membrane made of polytetrafluorethylene, due to high relevance of such researches owing toreduce the risk of infection of surgical wounds and high degree of adaptation to the geometry of the bone defect.

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