scholarly journals Observation on the Effect of Bone Grafting Alone and Guided Tissue Regeneration Combined with Bone Grafting to Repair Periodontal Intraosseous Defects

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Yongping Yuan ◽  
Jiajia Zhao ◽  
Nv He

Objective. To investigate the curative effect of guided tissue regeneration (GTR) combined with bone grafting and improve the aesthetic appearance of patients’ gingiva. Methods. A total of 86 patients with periodontal intraosseous defects were selected from February 2019 to February 2021. All the patients were divided into a control group and an observation group according to the random number table, with 43 patients in each group. Bone grafting was performed in the control group, while GTR was additionally used in the observation group on the basis of the control group. The surgical data and follow-up data were collected and organized. The alveolar bone mineral density, the change in the height of the bone defect, plaque index (PLI), sulcus hemorrhage index (SBI), PD, gingival recession (GR), clinical attachment loss (CAL), and other relevant data of the two groups in 6 months before and after surgery were compared. Six months after surgery, the cosmetic morphology of the patient's gums in the soft tissues around her teeth was evaluated. Results. Six months after surgery, the alveolar bone density of patients in two groups increased compared with that before surgery, and the height of the bone defect decreased compared with that before surgery. The alveolar bone density of the observation group was higher than that of the control group, and the height of the bone defect was lower than that of the control group ( P < 0.05 ). Six months after surgery, the PLI, SBI, PD, and CAL of patients in both groups were lower than those before surgery, while the GR was higher than that before surgery. PD and CAL values in the observation group were lower than those in the control group, and GR was higher than that in the control group ( P < 0.05 ). Six months after surgery, there was no significant difference in PLI and SBI scores between the two groups ( P < 0.05 ). Six months after surgery, the gingival cosmetic scores of the two groups of patients were higher than those before surgery. The observation group was higher than the control group ( P < 0.05 ). Conclusion. GTR combined with bone grafting has a good effect in the repair of periodontal intraosseous defects and can effectively promote the reconstruction and recovery of periodontal intraosseous defects in patients. At the same time, it can significantly improve the aesthetic appearance of patients’ gums, with good clinical application value.

2010 ◽  
Vol 04 (04) ◽  
pp. 403-411 ◽  
Author(s):  
Gonca Cayir Keles ◽  
Mahmut Sumer ◽  
Burcu Ozkan Cetinkaya ◽  
Ferda Tutkun ◽  
S. Burcak Simsek

Objectives: The aim of this clinical trial was to evaluate the additional benefit of using guided tissue regeneration (GTR) with autogenous cortical bone (ACB) grafting versus ACB grafting alone for the regenerative treatment of intraosseous periodontal defects.Methods: Via a split-mouth design, 12 patients with chronic periodontitis (five men, seven women; mean age, 45.3±4.6 years) who had probing pocket depths (PPDs) of ≥6 mm following initial periodontal therapy were randomly assigned to two treatments in contralateral areas of the dentition: a combination of ACB grafting and GTR (with a absorbable membrane of polylactic acid) or ACB grafting alone. The compared parameters were preoperative and 6-month postoperative PPDs, clinical attachment levels (CALs), and radiographic alveolar bone heights.Results: Both treatment modalities resulted in significant changes in the postoperative measurements from the preoperative values (P<.01). The reduction in the PPDs, gain in the CALs, and gain in the radiographic alveolar bone heights were 4.58±1.08, 4.25±1.06, and 5.50±2.24 mm in the patients treated with ACB grafting and GTR and 4.92±1.00, 4.50±0.80, and 5.92±1.83 mm in those treated with ACB grafting alone, respectively. The differences between the treatments were not statistically significant (P>.05).Conclusions: Within the study limitations, both ACB grafting with GTR and ACB grafting alone lead to significant improvements in clinical and radiographic parameters at 6 months postoperatively. The combined approach does not provide any additional benefit for treating intraosseous periodontal defects. (Eur J Dent 2010;4:403-411)


Author(s):  
I. Mecuku ◽  
A. A Muraev ◽  
Julia V. Gazhva ◽  
S. G Ivashkevich

This review aims to analyze the domestic and foreign professional literature, and it shows the main positive and negative properties of the materials for the manufacture of membranes used in modern dental practice in bone-grafting interventions and guided tissue regeneration. Emphasis is placed on the importance of developing a new individual membrane made of polytetrafluorethylene, due to high relevance of such researches owing toreduce the risk of infection of surgical wounds and high degree of adaptation to the geometry of the bone defect.


2007 ◽  
Vol 44 (5) ◽  
pp. 469-475 ◽  
Author(s):  
Julia K. Scott ◽  
Roger M. Webb ◽  
Timothy R. Flood

Objective: To introduce a surgical technique for secondary alveolar bone grafting performed in conjunction with premaxillary osteotomy and guided tissue regeneration in children with bilateral clefts. This paper also looks at the outcomes of this surgery in a series of 15 consecutive patients. Methods: Secondary alveolar bone grafting (with a premaxillary osteotomy and guided tissue regeneration with a collagen membrane) is usually carried out in the mixed dentition stage. This retrospective study used patients’ medical records, radiographs, and clinical examination to assess the outcome of the surgery. Patients were followed up for an average of 3 years. Results: Bone grafting was successful in all cases. No premaxillae were lost and there was no long-term morbidity of the donor site. Radiographic assessment of the bone heights showed an average of 94% retention, 3 months postoperatively. Preliminary assessment of maxillary canine eruption is encouraging, with 79% being fully erupted in those patients who are at least 3 years post–bone grafting. Conclusion: Premaxillary osteotomy allows repositioning of the premaxilla to its optimal preplanned position and successful closure of all fistulae. We have found that use of a collagen membrane is a useful adjunct.


2008 ◽  
Vol 65 (6) ◽  
pp. 462-468 ◽  
Author(s):  
Milos Duka ◽  
Zoran Lazic ◽  
Marija Bubalo

Background/Aim. Osseointegration is a result of cellular migration, differentiation, bone formation, and bone remodeling on the surface of an implant. Each of these processes depends on platelets and blood coagulum. Platelet-rich plasma (PRP) is used to improve osseointegration and stability of implants. The aim of the research was to test the influence that PRP and guided tissue regeneration in bone defects have on bone defect filling and the level of bone resorption in early implant insertion. Methods. This experimental study included 10 dogs. A total of 40 BCT implants were inserted, 4 in each dog (two on the left side and two on the right side), with guided tissue regeneration. Radiologic analyses were done immediately after the insertion and 10 weeks after the insertion. Bone defect filling was measured by a graduated probe 10 weeks after the implant insertion. The following protocols were tested: I - PRP in combination with bovine deproteinized bone (BDB) and resorptive membrane of bovine origin (RBDM), II - BDB + RBDM, III - PRP + RBDM and IV - RBDM. Results. The applied protocols affected differently the bone defect filling and the level of bone resorption. Significantly better results (the lowest bone resorption) were achieved with protocol I (PRP + BDB + RBDM) in comparison with protocols III (PRP + RBDM) and IV (RBDM), but not with protocol II (BDB + RBDM). On the other hand, no significant difference was found among protocols II (BDB + RBDM), III (PRP + RBDM) and IV (RBDM) in the level of bone tissue resorption. Conslusion. The bone defect filling was largest and the level of bone resorption was lowest in the protocol with PRP applied in combination with BDB and RBDM.


2010 ◽  
Vol 43 (3) ◽  
pp. 141
Author(s):  
Sri Kentjananingsih

Background: Tooth extraction can cause alveolar resorption, and will reduce the denture retention. The process of bone resorption looks like the process of osteoporosis. Calcium and vitamin D supplementation is the rational therapy for minimizing bone loss. Miacalcic is the drug of choice for osteporotic patient. Purpose: This study is aimed to know whether the combination of miacalcic, calcium lactate, and vitamin C are effective in inhibiting post extracted alveolar resorption. Methods: Thirty three healthy postmenopausal women were chosen as samples and they were classified randomly into control group (without treatment), 1st experiment group (treatment was started 3 months post extraction), and 2nd experiment group (treatment was started at the 2nd day post extraction). The treatment was done by giving miacalcic nasal spray, calcium lactate 500 mg and vitamin C 100 mg tablets every morning in 10 days every month for 3 months. X-ray photo of the post extracted area were taken an hour, 3 months, and 6 months post-extraction. Results: After 6 month, there was significant difference in buccolingual thickness decreasing among three groups (p<0.05). The maximum mean difference of buccolingual thickness decreasing was 0.72 mm, between control and 2nd experiment groups. There was no significant difference about decreasing bone density among them (p>0.10). The maximum difference of the mean of density decreasing was 1,906 g/cm2/mm between control and 2nd experiment groups. The increasing density mostly occurred in the 2nd experiment group. Conclusion: The combination of miacalcic, calcium lactate, and vitamin C are effective for inhibiting alveolar resorption, although statistically there was no significant difference about bone density decreasing. The sooner this treatment is given the better result will be achieved.Latar belakang: Pencabutan gigi menyebabkan resorpsi tulang alveolaris, dan akan mengurangi retensi geligi tiruan. Proses resorpsi tulang alveol pada osteoporosis mirip dengan proses resorpsi tulang pada penyembuhan luka bekas pencabutan. Miacalcic adalah obat utama untuk penderita osteoporosis. Kalsium dan vitamin D merupakan terapi yang rasional untuk meminimalkan resorpsi tulang. tujuan: Membuktikan apakah kombinasi miacalcic, kalsium laktat, and vitamin C juga efektif menghambat resorpsi tulang alveol pasca pencabutan. Metode: Sampel 33 wanita postmenopause yang sehat, terbagi secara acak ke dalam kelompok kontrol (tanpa perlakuan), kelompok eksperimen 1 (perlakuan mulai 3 bulan pasca pencabutan) dan kelompok eksperimen 2 (perlakuan mulai hari kedua pasca pencabutan). Perlakuannya yaitu: pemberian miacalcic semprot hidung, tablet kalsium laktat 500 mg dan vitamin C 100 mg setiap pagi, 10 hari dalam sebulan, selama tiga bulan. Foto sinar-X dari regio pasca pencabutan dibuat satu jam, 3 bulan, dan 6 bulan pasca pencabutan. Hasil: 6 bulan pasca-cabut, ada beda bermakna perihal selisih tebal bukolingual tulang alveol antar ketiga kelompok (p<0,05). Rerata penurunan ketebalan ini maksimal sebanyak 0.72 mm, antara kelompok kontrol dan kelompok eksperimen 2. Penurunan kepadatan tulang antar ketiga kelompok tidak bermakna (p>0,10). Beda maksimum rerata kepadatan tulang antara kelompok kontrol dan kelompok eksperimen 2 sebesar 1,906 g/cm2/mm. Peningkatan kepadatan terbanyak dialami anggota kelompok eksperimen 2. Kesimpulan: Kombinasi miacalcic, kalsium laktat, vitamin C efektif menghambat resorpsi tulang alveolaris, walaupun secara statistik beda penurunan kepadatan tidak bermakna. Makin awal pemberian perlakuan, hasilnya akan lebih baik.


2020 ◽  
Vol 10 (5) ◽  
pp. 737-742
Author(s):  
Jianxing Han ◽  
Junping Dong ◽  
Hua Zhao ◽  
Yuan Ma ◽  
Shuoran Yang ◽  
...  

Objective: To assess the effect of periodontal tissue regeneration combined with orthodontic treatment on periodontitis and inflammatory factors. Methods : 100 patients with periodontitis were randomly separated into observation group and control group. Patients were treated with periodontal tissue regeneration in control group and received orthodontic treatment in observation group. The periodontal indexes, X-ray cephalometric indexes, serum inflammatory factor levels, tooth mobility, the postoperative complications, efficacy and life quality were measured. Results: After treatment, levels of clinical attachment loss (CAL), probing depth (PD), sulcus bleeding index (SBI), gingival index (GI), plaque index (PLI), SNB angle, SNA angle, IL-8, IL-5, TNF-α and hs-CRP of patients in observation group were significantly decreased, while ANB angle was significantly elevated (p < 0 05). Meanwhile, the treatment effective rate and quality of life score was significantly improved after treatment in observation group (p < 0 05). Conclusion: Periodontal tissue regeneration combined with orthodontic treatment can significantly improve periodontitis symptoms, promote the recovery of tooth function, reduce inflammation and postoperative complications, and improve the uniformity and appearance of teeth in patients with periodontitis.


2009 ◽  
Vol 46 (1) ◽  
pp. 9-18 ◽  
Author(s):  
Tomohisa Nagasao ◽  
Hisao Ogata ◽  
Junpei Miyamoto ◽  
Hua Jiang ◽  
Tsuyoshi Kaneko ◽  
...  

Objective: This is a retrospective study regarding the effect of alveolar bone grafting (ABG) on morphological changes in the bony structure of the nose in alveolar and palatal cleft patients. Methods: Sixty-five randomly selected adults were included in the present study. Of the 65 subjects, 21 had no congenital anomaly and were designated as the control group (n  =  21; mean age 22.4 ± 4.3 years). Forty-four had unilateral complete clefts of the alveolus and palate on the left side. The patients with clefts were further divided into two subgroups based on presence or absence of ABG in their histories. These groups were termed the ABG(+) group (n  =  24; mean age 20.3 ± 2.5 years) and the ABG(−) group (n  =  20; mean age 32 ± 4.5 years), respectively. An anatomical structure that constitutes the bony component of the nose was defined. This structure, composed of the nasal bones and part of the frontal process of the maxilla, was termed the BSEN (bony structure of the external nose). The symmetry of the BSEN was assessed quantitatively by performing morphological measurements on computerized tomographic images of each patient's skull, and these measurements were compared among the control, ABG(+), and ABG(−) groups. Results: The BSEN presented more symmetric features in the ABG(+) group patients than in the ABG(−) group patients. Conclusion: ABG improves symmetry of the BSEN. This finding justifies ABG in terms of cosmetic improvement of the external nose in patients with unilateral complete alveolar and palatal clefts.


2021 ◽  
Vol 11 (4) ◽  
pp. 1474-1484
Author(s):  
Giulio Gabrieli ◽  
Gianluca Esposito

To curb the diffusion of the novel coronavirus (SARS-CoV-2), governments worldwide have introduced different policies, including lockdowns, social distancing, and mandatory mask wearing. Face mask wearing, especially, has an impact on the formation of first impressions, given that when meeting someone for the first time, individuals rely on the only available piece of information, the newly met person’s aesthetic appearance, in order to make initial estimations of other traits, such as competence, intelligence, or trustworthiness. However, face mask wearing affects the aesthetic appearance of an individual, creating uncertainty which, in turn, has been reported to reduce others’ perceived trustworthiness. In this paper, the influence of face mask wearing on strangers’ perceived trustworthiness and aesthetic appearance is assessed to verify the impact of this policy on impression formation. Participants (N = 71) have been instructed to assess the trustworthiness and the aesthetic appearance of a selection of 96 images depicting individuals of different ages (children, adults, and older adults), gender (men and women), and ethnicity (Asians or Caucasians). Participants were randomly divided into two groups: an experimental group and a control group. Participants in the experimental group (N = 38) rated faces of individuals wearing a face mask, while participants in the control group rated the same faces but in the absence of a face mask. Images were presented in random order. For each face, participants were asked to rate the aesthetic appearance and perceived trustworthiness of the stranger on two different 100-point Likert scales. Results demonstrate that (i) the correlation between perceived trustworthiness and aesthetic appearance is not affected by the presence of a face mask, and (ii) age, but not ethnicity and gender, influences the magnitude of differences in perceived trustworthiness levels during mask wearing.


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