scholarly journals Fournier′s gangrene of the penis

2005 ◽  
Vol 38 (02) ◽  
pp. 154-156
Author(s):  
Francis Leo Tauro ◽  
M Roshan ◽  
B S Sathish Rao ◽  
J Ravikrishnan ◽  
Leo T Menezes
Keyword(s):  
Abdominal Wall ◽  
Broad Spectrum ◽  
Normal Skin ◽  
Skin Grafting ◽  
Early Therapy ◽  
Broad Spectrum Antibiotics ◽  
Localized Disease

ABSTRACTFournier′s gangrene is a rare, fulminant, though generally localized disease of the scrotum and penis with occasional extension up the abdominal wall. The usual organism is an anaerobic streptococcus synergistic with some second organism. Our case was unusual in that only the penis was involved without involving the scrotum or abdominal wall. Early therapy is the key, including hospitalization, debridement of entire shaft of the penis distal to the devasted area without excising the normal skin, parenteral broad-spectrum antibiotics & skin grafting. Only few cases of Fournier′s gangrene of the penis have been reported.

scholarly journals Mycobacterium fortuitum abdominal wall abscesses following liposuction

2008 ◽  
Vol 41 (01) ◽  
pp. 58-61
Author(s):  
Hussam Al Soub ◽  
Eman Al-Maslamani ◽  
Mona Al-Maslamani
Keyword(s):  
Antibiotic Therapy ◽  
Abdominal Wall ◽  
Broad Spectrum ◽  
Mycobacterium Fortuitum ◽  
Surgical Drainage ◽  
Abdominal Abscesses ◽  
Broad Spectrum Antibiotics

ABSTRACTwe describe here a case of abdominal abscesses due to mycobacterium fortuitum following liposuction. the abscesses developed three months after the procedure and diagnosis was delayed for five months. the clues for diagnosis were persistent pus discharge in spite of broad spectrum antibiotics and failure to grow any organisms on routine culture. this condition has been rarely reported; however, the increasing number of liposuction procedures done and awareness among physicians will probably result in the identification of more cases. combination antibiotic therapy with surgical drainage in more extensive diseases is essential for cure.

scholarly journals Fourniers gangrene-A case report and literature review

2012 ◽  
Vol 7 (3) ◽  
pp. 62-67
Author(s):  
A Agarwal ◽  
A Karmacharaya ◽  
S Hirachan ◽  
WK Belokar
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Broad Spectrum ◽  
Skin Grafting ◽  
Multiple Organ ◽  
Medical Sciences ◽  
Anaerobic Microorganisms ◽  
Broad Spectrum Antibiotics ◽  
Appropriate Therapy ◽  
Aerobic And Anaerobic

Fournier’s gangrene(FG) is a rare, necrotising fasciitis of the genitals and perineum with occasional cranial extension to the abdominal wall caused by a mixture of aerobic and anaerobic microorganisms. The complications of this synergistic infection are multiple organ failure and death. Due to the aggressive nature of this condition, early diagnosis is crucial. Treatment involves extensive soft tissue debridement and broad-spectrum antibiotics. Despite appropriate therapy, mortality is high. We report a case of a gentleman who presented with gangrenous and necrotic penile, scrotal and perineal areas. Patient was successfully managed by extensive soft tissue debridement, broad spectrum antibiotics and skin grafting. DOI: http://dx.doi.org/10.3126/jcmsn.v7i3.6713 Journal of College of Medical Sciences-Nepal, 2011, Vol-7, No-3, 62-67 

Possible Heparin-Inouceo Subcutaneous Necrosis in a CAPO Patient

1987 ◽  
Vol 7 (3) ◽  
pp. 187-189 ◽  
Author(s):  
Peter J. Somerville ◽  
Elizabeth O'Brien ◽  
Michael Kaye
Keyword(s):  
At Risk ◽  
Peritoneal Dialysis ◽  
Abdominal Wall ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Broad Spectrum ◽  
Anterior Abdominal Wall ◽  
Broad Spectrum Antibiotics

A patient developed subcutaneous necrosis of the tissue of the anterior abdominal wall while carrying out continuous ambulatory peritoneal dialysis (CAPD). This necrosis was preceded by a leak of heparin-containing dialysate into the area. We believe this represents an example of the entity -heparin-induced subcutaneous necrosis. After reviewing the appropriate literature, we have concluded that intraperitoneal heparin should be used with caution in CAPD patients, who are at risk for leakage and heparin necrosis, i.e. those who are diabetic, elderly, obese, and receiving broad spectrum antibiotics.

scholarly journals Trends in Antibiotic Prescribing in Out-of-Hours Primary Care in England from January 2016 to June 2020 to Understand Behaviours during the First Wave of COVID-19

Antibiotics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 32
Author(s):  
Nina J. Zhu ◽  
Monsey McLeod ◽  
Cliodna A. M. McNulty ◽  
Donna M. Lecky ◽  
Alison H. Holmes ◽  
...  
Keyword(s):  
Primary Care ◽  
Time Series ◽  
Patient Outcomes ◽  
Broad Spectrum ◽  
Antibiotic Prescribing ◽  
Broad Spectrum Antibiotic ◽  
Out Of Hours ◽  
Broad Spectrum Antibiotics ◽  
National Quality ◽  
General Practices

We describe the trend of antibiotic prescribing in out-of-hours (OOH) general practices (GP) before and during England’s first wave of the COVID-19 pandemic. We analysed practice-level prescribing records between January 2016 to June 2020 to report the trends for the total prescribing volume, prescribing of broad-spectrum antibiotics and key agents included in the national Quality Premium. We performed a time-series analysis to detect measurable changes in the prescribing volume associated with COVID-19. Before COVID-19, the total prescribing volume and the percentage of broad-spectrum antibiotics continued to decrease in-hours (IH). The prescribing of broad-spectrum antibiotics was higher in OOH (OOH: 10.1%, IH: 8.7%), but a consistent decrease in the trimethoprim-to-nitrofurantoin ratio was observed OOH. The OOH antibiotic prescribing volume diverged from the historical trend in March 2020 and started to decrease by 5088 items per month. Broad-spectrum antibiotic prescribing started to increase in OOH and IH. In OOH, co-amoxiclav and doxycycline peaked in March to May in 2020, which was out of sync with seasonality peaks (Winter) in previous years. While this increase might be explained by the implementation of the national guideline to use co-amoxiclav and doxycycline to manage pneumonia in the community during COVID-19, further investigation is required to see whether the observed reduction in OOH antibiotic prescribing persists and how this reduction might influence antimicrobial resistance and patient outcomes.

scholarly journals Oral Antibiotic for Empirical Management of Acute Dentoalveolar Infections—A Systematic Review

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 240
Author(s):  
Leanne Teoh ◽  
Monique C Cheung ◽  
Stuart Dashper ◽  
Rodney James ◽  
Michael J McCullough
Keyword(s):  
Systematic Review ◽  
Clinical Outcomes ◽  
Broad Spectrum ◽  
Dental Treatment ◽  
Clinical Success ◽  
Empirical Therapy ◽  
Oral Antibiotic ◽  
Dose Frequency ◽  
Odontogenic Infections ◽  
Broad Spectrum Antibiotics

Concerns regarding increasing antibiotic resistance raise the question of the most appropriate oral antibiotic for empirical therapy in dentistry. The aim of this systematic review was to investigate the antibiotic choices and regimens used to manage acute dentoalveolar infections and their clinical outcomes. A systematic review was undertaken across three databases. Two authors independently screened and quality-assessed the included studies and extracted the antibiotic regimens used and the clinical outcomes. Searches identified 2994 studies, and after screening and quality assessment, 8 studies were included. In addition to incision and drainage, the antibiotics used to manage dentoalveolar infections included amoxicillin, amoxicillin/clavulanic acid, cefalexin, clindamycin, erythromycin, metronidazole, moxifloxacin, ornidazole and phenoxymethylpenicillin. Regimens varied in dose, frequency and duration. The vast majority of regimens showed clinical success. One study showed that patients who did not receive any antibiotics had the same clinical outcomes as patients who received broad-spectrum antibiotics. The ideal choice, regimen and spectrum of empirical oral antibiotics as adjunctive management of acute dentoalveolar infections are unclear. Given that all regimens showed clinical success, broad-spectrum antibiotics as first-line empirical therapy are unnecessary. Narrow-spectrum agents appear to be as effective in an otherwise healthy individual. This review highlights the effectiveness of dental treatment to address the source of infection as being the primary factor in the successful management of dentoalveolar abscesses. Furthermore, the role of antibiotics is questioned in primary space odontogenic infections, if drainage can be established.

scholarly journals Evaluation of Clinical Outcomes after Introduction of a Dedicated Infectious Diseases- Critical Care Medicine Service in Critical Care Units

2021 ◽  
Author(s):  
Polina Trachuk ◽  
Vagish Hemmige ◽  
Ruth Eisenberg ◽  
Kelsie Cowman ◽  
Victor Chen ◽  
...  
Keyword(s):  
Critical Care ◽  
Infectious Diseases ◽  
Clinical Outcomes ◽  
Broad Spectrum ◽  
Critical Care Medicine ◽  
Care Hospital ◽  
Intervention Period ◽  
Broad Spectrum Antibiotics ◽  
Antibiotic Utilization ◽  
The Impact

Abstract Objective Infection is a leading cause of admission to intensive care units (ICU), with critically ill patients often receiving empiric broad-spectrum antibiotics. Nevertheless, a dedicated infectious diseases (ID) consultation and stewardship team is not routinely established. An ID-Critical Care Medicine (ID-CCM) pilot program was designed at a 400-bed tertiary care hospital in which an ID attending was assigned to participate in daily rounds with the ICU team, as well as provide ID consultation on select patients. We sought to evaluate the impact of this dedicated ID program on antibiotic utilization and clinical outcomes in patients admitted to the ICU. Method In this single site retrospective study, we analyzed antibiotic utilization and clinical outcomes in patients admitted to an ICU during post-intervention period from January 1, 2017 to December 31, 2017 and compared it to antibiotic utilization in the same ICUs during the pre-intervention period from January 1, 2015 to December 31, 2015. Results Our data showed a statistically significant reduction in usage of most frequently prescribed antibiotics including vancomycin, piperacillin-tazobactam and cefepime during the intervention period. When compared to pre-intervention period there was no difference in-hospital mortality, hospital length of stay and re-admission. Conclusion With this multidisciplinary intervention, we saw a decrease in the use of the most frequently prescribed broad-spectrum antibiotics without a negative impact on clinical outcomes. Our study shows that the implementation of an ID-CCM service is a feasible way to promote antibiotic stewardship in the ICU and can be used as a strategy to reduce unnecessary patient exposure to broad-spectrum agents.

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