scholarly journals Association between Gastric Cancer with Behavioral and Dietary Factors: A Hospital Based Case-Control Study in South Asia

2021 ◽  
Author(s):  
Arun Shahi ◽  
Venkata Pradeep Babu Koyyala ◽  
Ela Singh Rathaur ◽  
Md. Assaduzaman Biddut ◽  
Anwor Hossain ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Red Meat ◽  
Dietary Factors ◽  
Inverse Association ◽  
Effective Prevention ◽  
Regular Consumption ◽  
History Of ◽  
Control Study

Abstract Background Gastric cancer (GC) is one of the most common malignancies and a leading cause of mortality and morbidity worldwide. It is the fourth leading cancer in Bangladesh. Identification of risk factors, effective prevention, and early diagnosis are the most important interventions against GC. Objectives To find an association of dietary and behavioral factors in the development of GC among the Bangladeshi population. Methods This case–control study was conducted from January 2017 to December 2018 at the National Institute of Cancer Research and Hospital, Dhaka, Bangladesh. A total of 178 patients were studied (89 case and 89 controls). Data were collected via face-to-face interview using a standard structured questionnaire, posing questions about socio-demographic, behavioral and dietary habits, and clinical factors. A binary logistic regression method was used to calculate the odds ratio (OR). Results Among 178 patients, the age group ranged from 30 to 80 years and most patients were between 51 to 60 years. The results showed that regular consumption of red meat, duration of smoking, smokeless tobacco, fast food and fatty food, and family history of any type of cancer were directly associated with the risk of GC. On the contrary, a habit of regular walking and playing sports has an inverse association with GC. Adjusted OR shows regular consumption of red meat has 2.6 times more risk (OR = 2.661) of developing GC compared with irregular meat consumption, and a person with a history of Helicobacter pylori infection is 53% (OR = 7.263; 95% confidence interval: 3.614–14.597) more likely to develop cancer. In contrast, people who were doing exercise regularly for at least 30 minutes/day are 62.7% (OR = 0.373) less likely to develop GC than those who did not. Conclusion The study showed an association of some dietary and behavioral factor in the development of GC. However, more research in this field is required to understand the etiology, for the development of suitable screening test, for demarcation of high-risk population, and to develop and evaluate the effectiveness of primary prevention programs.

scholarly journals The effect of raw vegetable and fruit intake on thyroid cancer risk among women: a case–control study in South Korea

2012 ◽  
Vol 109 (1) ◽  
pp. 118-128 ◽  
Author(s):  
Su Kyoung Jung ◽  
Kirang Kim ◽  
Kyung Tae ◽  
Gu Kong ◽  
Mi Kyung Kim
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Early Stage ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Dietary Factors ◽  
Inverse Association ◽  
Thyroid Cancer Risk ◽  
Control Study

Thyroid cancer is the most common cancer among Korean women. However, there are few data on dietary factors related to thyroid cancer risk. The objective of the present study was to evaluate the association between raw vegetables and fruits intake and thyroid cancer in a case–control study. We included 111 histologically confirmed malignant thyroid cancer cases and 115 benign cases. Controls who did not have nodules in thyroid ultrasonography were matched to cases by age ( ± 2 years). Food and nutrient intakes were estimated using a quantitative FFQ with 121 items. Conditional logistic regression analysis was used to obtain OR and corresponding 95 % CI. The intake of total vegetables was not associated with malignant thyroid cancer, but inversely associated with benign cases. High raw vegetable intake was inversely associated with thyroid cancer risk both in malignant and benign cases (P for trend = 0·01 in both malignant and benign cases). Among fruits, persimmon intake had an inverse association with thyroid cancer risk in both malignant and benign cases (P for trend = 0·06 in malignant cases; P for trend = 0·01 in benign cases) and tangerine intake had an inverse association in malignant cases (P for trend = 0·03). The frequency of consumption of raw vegetables and persimmon also had a consistent inverse association in both malignant and benign cases. These results suggest that high consumption of raw vegetables, persimmons and tangerines may decrease thyroid cancer risk and help prevent early-stage thyroid cancer.

scholarly journals A case–control study on red meat consumption and risk of stroke among a group of Iranian adults

2014 ◽  
Vol 18 (6) ◽  
pp. 1084-1090 ◽  
Author(s):  
Parvane Saneei ◽  
Mohammad Saadatnia ◽  
Forough Shakeri ◽  
Masumeh Beykverdi ◽  
Ammar Hassanzadeh Keshteli ◽  
...  
Keyword(s):  
Case Control Study ◽  
Meat Consumption ◽  
Cerebrovascular Diseases ◽  
Case Control ◽  
Red Meat ◽  
Dietary Intakes ◽  
Stroke Patients ◽  
Meat Intake ◽  
History Of ◽  
Control Study

AbstractObjectiveWe aimed to examine the association between red meat consumption and stroke in a group of Iranian adults.DesignA hospital-based case–control study.SettingThe study included stroke patients and hospital-based controls. Usual dietary intakes of participants were assessed by means of a validated 168-item semi-quantitative FFQ. Total red meat consumption was calculated by summing up the consumption of red, processed and visceral meats.SubjectsOne hundred and ninety-five cases were stroke patients hospitalized in the neurology ward and 195 controls were recruited from patients hospitalized in other wards with no history of cerebrovascular diseases or neurological disorders.ResultsParticipants with stroke were older, more likely to be male and less likely to be obese. Individuals in the highest tertile of red meat intake were 119 % more likely to have stroke (OR=2·19; 95 % CI 1·33, 3·60) compared with those in the lowest tertile. After controlling for age, sex and total energy intake, the association between red meat consumption and stroke was strengthened (OR=2·72; 95 % CI 1·53, 4·83). This association remained significant even after further controlling for physical activity and smoking as well as dietary intakes. Additional adjustments for BMI, diabetes, hypertension and hyperlipidaemia did not influence the association significantly (OR=2·51; 95 % CI 1·19, 5·09).ConclusionsConsumption of red meat was associated with greater odds of having stroke in a group of Iranian adults.

scholarly journals Association Between Dietary Phytochemical Index and Breast Cancer: a Case-control Study

2020 ◽  
Author(s):  
Seyed Mojtaba Ghoreishy ◽  
Azadeh Aminianfar ◽  
Sanaz Benisi-Kohansal ◽  
Leila Azadbakht ◽  
Ahmad Esmaillzadeh
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Cluster Method ◽  
Inverse Association ◽  
Dietary Intakes ◽  
Crude Model ◽  
Disease Associations ◽  
History Of ◽  
Control Study

Abstract Background: Dietary intake of isoflavones has been positively associated with risk of breast cancer (BC) in some earlier studies. In addition, most studies on diet-disease associations came from western countries and limited data are available in the Middle-East. Methods: This case-control study was performed on 350 women with breast cancer aged over 30 years old who were recruited from hospitals or private clinics in Isfahan, Iran. All patients were diagnosed with BC during the maximum of the last 6 months using physical examination and mammography findings. Using cluster method sampling, 700 apparently healthy age- and socioeconomic status-matched controls were randomly selected from healthy women who had no relationship with BC patients and had no familial history of BC. Data on dietary intakes were collected using a validated food frequency questionnaire. The DPI was calculated based on dietary energy derived from foods rich in phytochemicals (kcal) divided by total daily energy intake (kcal) of each participant. Results: Mean ± SD age and BMI in the study participants were 62.4±10.8 y and 24.3±5.2 kg/m2, respectively. In the crude model, participants in the highest quartile of DPI had 63% lower odds of breast cancer compared to those in the lowest quartile (95% CI: 0.26, 0.54; P-trend <0.001). After adjustment for potential confounders, this inverse association became strengthened (95% CI: 0.22, 0.49; P-trend <0.001). Further adjustment for BMI did not change the association (OR for the highest quartile vs. the lowest quartile = 0.40, 95% CI: 0.26, 0.60; P-trend <0.001). Conclusion: In conclusion, a protective association was observed between DPI and BC in this case-control study. Therefore, high consumption of foods rich in phytochemicals such as fruits, vegetables and whole grains might help reducing the odds of BC among women.

Dietary factors and gastric cancer in Korea: A case-control study

2002 ◽  
Vol 97 (4) ◽  
pp. 531-535 ◽  
Author(s):  
Hyun Ja Kim ◽  
Woong Ki Chang ◽  
Mi Kyung Kim ◽  
Sang Sun Lee ◽  
Bo Youl Choi
Keyword(s):  
Gastric Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Dietary Factors ◽  
Control Study

scholarly journals Plasma alkylresorcinol metabolite, a biomarker of whole-grain wheat and rye intake, and risk of ischemic stroke: a case-control study

2019 ◽  
Vol 109 (2) ◽  
pp. 1-7 ◽  
Author(s):  
Taoping Sun ◽  
Yanwei Zhang ◽  
Hao Huang ◽  
Xiaoqian Wang ◽  
Li Zhou ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Stroke Risk ◽  
Case Control Study ◽  
Smoking Status ◽  
Case Control ◽  
Inverse Association ◽  
Whole Grain ◽  
History Of ◽  
Ischemic Stroke Risk ◽  
Control Study

ABSTRACT Background Epidemiologic studies on whole grains and risk of stroke have reported inconsistent results, with some suggesting a protective effect but others showing a null association. Objectives The aim of this study was to examine whether plasma 3-(3,5-dihydroxyphenyl)-1-propanoic acid (DHPPA), a biomarker of whole-grain wheat and rye intake, is associated with risk of ischemic stroke. Methods A hospital-based case-control study was conducted between March 2011 and May 2016. Cases (n = 990) with first ischemic stroke were matched to controls (n = 990) by sex and age. Concentrations of plasma DHPPA were determined by high-performance liquid chromatography–tandem mass spectrometry. We calculated ORs for the association of plasma DHPPA concentrations with ischemic stroke risk through the use of logistic regression. Results Plasma DHPPA was inversely associated with ischemic stroke risk. After adjustment for potential confounding factors, the ORs for ischemic stroke across increasing quartiles of plasma DHPPA concentrations were 1 (referent), 0.76 (95% CI: 0.58, 0.99), 0.71 (95% CI: 0.54, 0.92), and 0.59 (95% CI: 0.45, 0.77), respectively (P-trend = 0.001). The inverse association was also observed in all subgroups of participants according to sex, age, body mass index, smoking status, alcohol consumption, history of hypertension, and history of diabetes. Conclusions Our study showed that higher plasma DHPPA concentrations were associated with lower risk of ischemic stroke. This finding provides further evidence to support the health benefits of whole-grain consumption.

scholarly journals Dietary factors and gastric cancer risk. A case-control study in Spain

Cancer ◽  
1993 ◽  
Vol 71 (5) ◽  
pp. 1731-1735 ◽  
Author(s):  
Jose M. Ramón ◽  
Luis Serra ◽  
Carlos Cerdó ◽  
Joaquin Oromí
Keyword(s):  
Gastric Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Dietary Factors ◽  
Gastric Cancer Risk ◽  
Control Study

scholarly journals Dietary Carotenoids Intake and the Risk of Gastric Cancer: A Case—Control Study in Korea

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1031 ◽  
Author(s):  
Ji Hyun Kim ◽  
Jeonghee Lee ◽  
Il Ju Choi ◽  
Young-Il Kim ◽  
Oran Kwon ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Fruits And Vegetables ◽  
Case Control Study ◽  
Case Control ◽  
Cancer Center ◽  
Inverse Association ◽  
Tomato Ketchup ◽  
Center Hospital ◽  
H Pylori ◽  
Control Study

Although the incidence of gastric cancer (GC) has declined, it remains the second most common cancer in Korea. As a class of phytochemicals, carotenoids are fat-soluble pigments that are abundant in fruits and vegetables and have health-promoting properties, including cancer prevention effects. This case-control study investigated the effects of total dietary carotenoids, dietary carotenoid subclasses (α-carotene, β-carotene, β-cryptoxanthin, lutein/zeaxanthin, and lycopene), and foods contributing to the dietary intake of each carotenoid on the risk of GC. Four hundred and fifteen cases and 830 controls were recruited from the National Cancer Center Hospital in Korea between March 2011 and December 2014. A significant inverse association between total dietary carotenoids and GC risk was observed among women (odds ratio (OR) 0.56, 95% confidence interval (CI) 0.32–0.99). A higher intake of dietary lycopene was inversely associated with GC risk overall in the subjects (OR 0.60, 95% CI 0.42–0.85, p for trend = 0.012), men (OR 0.60, 95% CI 0.39–0.93), and women (OR 0.54, 95% CI 0.30–0.96, p for trend = 0.039). This significant association between dietary lycopene intake and GC risk was also observed in the subgroups of Helicobacter pylori (H. pylori)-positive subjects and those who had ever smoked. Among the major contributing foods of dietary lycopene, consumption of tomatoes and tomato ketchup was inversely associated with GC risk in the overall subjects, men, and women. Based on our findings, a higher intake of dietary lycopene and contributing foods of lycopene (tomatoes and tomato ketchup) may be inversely associated with the risk of GC.

scholarly journals Risk factors for early-onset colorectal cancer: a population-based case–control study in Ontario, Canada

2021 ◽  
Author(s):  
Vicky C. Chang ◽  
Michelle Cotterchio ◽  
Prithwish De ◽  
Jill Tinmouth
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Early Onset ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Dietary Factors ◽  
Supplement Use ◽  
History Of ◽  
Control Study

Abstract Purpose There has been an alarming increase in colorectal cancer (CRC) incidence among young adults aged < 50 years, and factors driving this upward trend are unknown. This study investigated associations between various medical, lifestyle, and dietary factors and risk of early-onset CRC (EO-CRC). Methods A population-based case–control study was conducted in Ontario, Canada during 2018–2019. EO-CRC cases aged 20–49 years (n = 175) were identified from the Ontario Cancer Registry; sex- and age group-matched controls (n = 253) were recruited through random digit dialing. Data on potential a priori risk factors were collected using a web-based self-reported questionnaire. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using multivariable logistic regression. Results Family history of CRC in a first- or second-degree relative (OR 2.37; 95% CI 1.47–3.84), longer sedentary time (≥ 10 vs. < 5 h/day, OR 1.93; 95% CI 1.02–3.65), greater consumption of sugary drinks (≥ 7 vs. < 1 drinks/week, OR 2.99; 95% CI 1.57–5.68), and a more Westernized dietary pattern (quartile 4 vs. 1, OR 1.92; 95% CI 1.01–3.66) were each associated with an increased risk of EO-CRC. Conversely, calcium supplement use (OR 0.53; 95% CI 0.31–0.92), history of allergy or asthma (OR 0.62; 95% CI 0.39–0.98), and greater parity in females (≥ 3 vs. nulliparity, OR 0.29; 95% CI 0.11–0.76) were each associated with a reduced risk. Conclusion Modifiable factors, particularly sedentary behavior and unhealthy diet including sugary drink consumption, may be associated with EO-CRC risk. Our findings, if replicated, may help inform prevention strategies targeted at younger persons.

scholarly journals Asthma and risk of glioma: a population-based case–control study

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e025746 ◽  
Author(s):  
Harsheen Kaur ◽  
Daniel H Lachance ◽  
Conor S Ryan ◽  
Youn Ho Sheen ◽  
Hee Yun Seol ◽  
...  
Keyword(s):  
Propensity Score ◽  
Index Date ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Inverse Association ◽  
Asthma Status ◽  
History Of ◽  
Community Controls ◽  
Control Study

ObjectivesLiterature suggests an inconsistent, but largely inverse, association between asthma and risk of glioma, which is primarily due to methodological inconsistency in sampling frame and ascertainment of asthma. The objective of the study was to clarify the association between asthma and risk of glioma by minimising methodological biases (eg, recall and detection bias).DesignA population-based case–control study.SettingGeneral population in Olmsted County, Minnesota, USA.ParticipantsAll eligible biopsy-proven incident glioma cases (1995–2014) and two sets of controls among residents matched to age and sex (first set: community controls without glioma; second set: MRI-negative controls from the same community).MethodsThe predetermined asthma criteria via medical record review were applied to ascertain asthma status of cases and controls. History of asthma prior to index date was compared between glioma cases and their matched controls using conditional logistic regression models. Propensity score for asthma status was adjusted for multivariate analysis.ResultsWe enrolled 135 glioma cases (median age at index date: 53 years) and 270 controls. Of the cases, 21 had a history of asthma (16%), compared with 36 of MRI controls (27%) (OR (95% CI) 0.48 (0.26 to 0.91), p=0.03). With MRI controls, an inverse association between asthma and risk of glioma persisted after adjusting for the propensity score for asthma status, but did not reach statistical significance probably due to the lack of statistical power (OR (95% CI) 0.48 (0.21 to 1.09); p=0.08). Based on comparison of characteristics of controls and cases, community controls seem to be more susceptible to a detection bias.ConclusionsWhile differential detection might account for the association between asthma and risk of glioma, asthma may potentially pose a protective effect on risk of glioma. Our study results need to be replicated by a larger study.

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