An innovative approach for blood oxygen monitoring by implantable diodes – first in vitro conclusions

2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
C Heilmann ◽  
J Fiala ◽  
S Reichelt ◽  
E Just ◽  
K Förster ◽  
...  
Keyword(s):  
Innovative Approach ◽  
Blood Oxygen ◽  
Oxygen Monitoring

scholarly journals Optical Measurement of Blood Oxygen Saturation of Dental Pulp

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Satoko Kakino ◽  
Shinya Kushibiki ◽  
Azusa Yamada ◽  
Zenzo Miwa ◽  
Yuzo Takagi ◽  
...  
Keyword(s):  
Light Intensity ◽  
Oxygen Saturation ◽  
Dental Pulp ◽  
Optical Measurement ◽  
Blood Oxygen ◽  
Arterial Pulse ◽  
Blood Oxygen Saturation ◽  
Visible Wavelengths

The applicability of arterial pulse oximetry to dental pulp was demonstrated using in vitro and in vivo measurements. First, porcine blood of known oxygen saturation (SO2) was circulated through extracted human upper incisors, while transmitted-light plethysmography was performed using three different visible wavelengths. From the light intensity waveforms measured in vitro, a parameter that is statistically correlated to SO2 was calculated using the pulsatile/nonpulsatile component ratios of two wavelengths for different SO2. Then, values were measured in vivo for living incisors, and the corresponding SO2 values were calculated using the results of in vitro measurements. The estimated SO2 values of the upper central incisors measured in vivo were from 71.0 to 92.7%. This study showed the potential to measure the oxygen saturation changes to identify the sign of pulpal inflammation.

scholarly journals Autosomal dominant polycythemia

Blood ◽  
1985 ◽  
Vol 66 (5) ◽  
pp. 1208-1214 ◽  
Author(s):  
JT Prchal ◽  
WM Crist ◽  
E Goldwasser ◽  
G Perrine ◽  
JF Prchal
Keyword(s):  
Autosomal Dominant ◽  
Oxygen Affinity ◽  
Colony Growth ◽  
Blood Oxygen ◽  
Autosomal Dominant Trait ◽  
Volume Measurements ◽  
Blood Oxygen Affinity ◽  
Low Levels ◽  
Stimulation Of

Two families with polycythemia inherited as an autosomal dominant trait are described. Serial hemoglobin determinations in multiple family members and RBC volume measurements in selected affected subjects documented their polycythemia. Measurements of arterial p02s, p50s, and blood oxygen affinity were normal in all affected individuals from each family who were tested. Erythropoietin (EPO) levels were low in affected individuals from family 1 and normal in affected members of family 2. Stimulation of in vitro CFU-E colony growth by low levels of EPO was significantly increased in subjects from family 1, but normal in those affected from family 2. We conclude that although the inheritance pattern for the polycythemia in both of these families appeared to be the same, the biologic defect leading to the disorder in each of these unique families was different. The precise mechanism of the increased EPO sensitivity noted in affected subjects from family 1 awaits elucidation.

scholarly journals Brain oxygen monitoring: in-vitro accuracy, long-term drift and response-time of Licox- and Neurotrend sensors

2005 ◽  
Vol 147 (7) ◽  
pp. 767-774 ◽  
Author(s):  
B. M. Hoelper ◽  
B. Alessandri ◽  
A. Heimann ◽  
R. Behr ◽  
O. Kempski
Keyword(s):  
Response Time ◽  
Brain Oxygen ◽  
Oxygen Monitoring

Postnatal regulation of canine oxygen delivery: erythrocyte components affecting Hb function

1980 ◽  
Vol 238 (1) ◽  
pp. H73-H79 ◽  
Author(s):  
P. A. Mueggler ◽  
G. Jones ◽  
J. S. Peterson ◽  
J. M. Bissonnette ◽  
R. D. Koler ◽  
...  
Keyword(s):  
Oxygen Affinity ◽  
Fetal Hemoglobin ◽  
Blood Oxygen ◽  
Oxygen Dissociation ◽  
Affinity Change ◽  
Blood Oxygen Affinity ◽  
Postnatal Change ◽  
2,3 Dpg

A rightward shift in the blood oxygen dissociation curve occurs during the 1st mo of canine life. A detailed peptide analysis indicated that dogs do not have a separate fetal hemoglobin. Other erythrocyte components such as ATP, K+, Na+, and H+ were excluded as significant mediators of the postnatal oxygen affinity change. Erythrocyte 2,3-DPG levels essentially zero in fetal dogs, increased rapidly during the 1st mo of canine life. There was a significant correlation between this postnatal 2,3-DPG increase and the postnatal decrease in blood oxygen affinity. Dialyzed hemolysates of fetal or adult canine blood have the same intrinsic oxygen affinity and the same response to normal adult levels of 2,3-DPG. Furthermore, the magnitude and direction of this 2,3-DPG-induced decrease in oxygen affinity in vitro are comparable to the in vivo postnatal change in oxygen affinity.

scholarly journals Self-Powered Flexible Blood Oxygen Monitoring System Based on a Triboelectric Nanogenerator

Nanomaterials ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 778 ◽  
Author(s):  
Huamin Chen ◽  
Yun Xu ◽  
Jiushuang Zhang ◽  
Weitong Wu ◽  
Guofeng Song
Keyword(s):  
Monitoring System ◽  
Sacrificial Layer ◽  
Triboelectric Nanogenerator ◽  
Blood Oxygen ◽  
Wearable Electronics ◽  
Output Performance ◽  
Supply Problem ◽  
Self Powered ◽  
Oxygen Monitoring ◽  
Functional Components

Flexible optoelectronics based on inorganic functional components have attracted worldwide attention due to their inherent advantages. However, the power supply problem presents a significant obstacle to the commercialization of wearable optoelectronics. Triboelectric nanogenerator (TENG) technology has the potential to realize self-powered applications compared to the conventional charging technologies. Herein, a flexible self-powered blood oxygen monitoring system based on TENG was first demonstrated. The flexibility of the TENG is mainly due to the inherent properties of polydimethylsiloxane (PDMS) and the continuously undulating surface of crumpled gold (Au) and the rough surface on the electrode and PDMS effectively increased the output performance. The output voltage, output current density, and power density were 75.3 V, 7.4 μA, and 0.2 mW/cm2, respectively. By etching the sacrificial layer, we then derived a flexible blood oxygen and pulse detector without any obvious performance degradation. Powered by the TENG, the detector is mounted onto the thumbnail, from where it detects a stable photoplethysmography (PPG) signal which can be used to calculate the oxyhemoglobin saturation and pulse rate. This self-powered system provides a new way to sustainably monitor physiological parameters, which paves the way for development of wearable electronics and battery-free systems.

Autosomal dominant polycythemia

Blood ◽  
1985 ◽  
Vol 66 (5) ◽  
pp. 1208-1214 ◽  
Author(s):  
JT Prchal ◽  
WM Crist ◽  
E Goldwasser ◽  
G Perrine ◽  
JF Prchal
Keyword(s):  
Autosomal Dominant ◽  
Oxygen Affinity ◽  
Colony Growth ◽  
Blood Oxygen ◽  
Autosomal Dominant Trait ◽  
Volume Measurements ◽  
Blood Oxygen Affinity ◽  
Low Levels ◽  
Stimulation Of

Abstract Two families with polycythemia inherited as an autosomal dominant trait are described. Serial hemoglobin determinations in multiple family members and RBC volume measurements in selected affected subjects documented their polycythemia. Measurements of arterial p02s, p50s, and blood oxygen affinity were normal in all affected individuals from each family who were tested. Erythropoietin (EPO) levels were low in affected individuals from family 1 and normal in affected members of family 2. Stimulation of in vitro CFU-E colony growth by low levels of EPO was significantly increased in subjects from family 1, but normal in those affected from family 2. We conclude that although the inheritance pattern for the polycythemia in both of these families appeared to be the same, the biologic defect leading to the disorder in each of these unique families was different. The precise mechanism of the increased EPO sensitivity noted in affected subjects from family 1 awaits elucidation.

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