Growth hormone response during OGTT: The impact of assay method, gender and BMI on the estimation of reference values in patients with acromegaly and in healthy controls

2007 ◽  
Vol 115 (S 1) ◽  
Author(s):  
AM Arafat ◽  
M Möhlig ◽  
MO Weickert ◽  
FH Perschel ◽  
J Purschwitz ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Reference Values ◽  
Growth Hormone Response ◽  
Assay Method ◽  
Healthy Controls ◽  
Hormone Response ◽  
The Impact

Menstrual cycle and oral contraceptives’ effects on growth hormone response to sprinting

2011 ◽  
Vol 36 (4) ◽  
pp. 495-502 ◽  
Author(s):  
Caroline Sunderland ◽  
Victoria Tunaley ◽  
Fleur Horner ◽  
Daniel Harmer ◽  
Keith A. Stokes
Keyword(s):  
Growth Hormone ◽  
Menstrual Cycle ◽  
Growth Hormone Response ◽  
Hormone Response ◽  
Menstrual Phase ◽  
Mean Power ◽  
Menstruating Women ◽  
Mean Power Output ◽  
The Impact ◽  
Midluteal Phase

The present study examined the impact of the menstrual cycle and oral contraceptive (OC) use on the growth hormone response to nonmotorized treadmill sprinting. Nine monophasic OC users (21.5 ± 4.7 years old), and 8 normally menstruating women (NM; 21.4 ± 2.9 years old) participated in the study. Each participant completed 2 main trials, each consisting of an all-out 30-s treadmill sprint. The NM group performed one trial in the midfollicular phase (NM follicular) and one in the midluteal phase (NM luteal); the OC group’s trials occurred one week into the start of the pill-taking cycle and once during the week in which pills were not taken.Venous blood samples were analyzed for growth hormone, pH, lactate, glucose, and progesterone concentrations. Peak and mean power output did not differ between the groups or with menstrual phase, or between the OC-free and OC trials. Integrated growth hormone was greater in the OC group than in the NM group (p = 0.04) with no phase difference (p = 0.80, mean (SD); NM follicular: 421 (335) and NM luteal: 345 (304) vs. OC free: 737 (471) and OC: 758 (389) µg·L–1·90 min–1). Blood lactate was higher in the OC group than in the NM group (p = 0.007) and, conversely, pH was lower in the OC group (p = 0.01). These results demonstrate that OC users who take high-androgenicity pills have a higher growth hormone response to sprint running than do normally menstruating women.

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