Role of plasma membrane surface charges in dictating the feasibility of membrane-nanoparticle interactions

2017 ◽  
Vol 111 (26) ◽  
pp. 263702 ◽  
Author(s):  
Shayandev Sinha ◽  
Haoyuan Jing ◽  
Harnoor Singh Sachar ◽  
Siddhartha Das
1977 ◽  
Vol 25 (5) ◽  
pp. 359-370 ◽  
Author(s):  
S K Aggarwal

Ascites sarcoma-180 cells, when stained with platinum-pyrimidine complexes as the sole electron dense stain, show distinct dense patches to granular appearance on the surface of the plasma membrane which has been suggested to be attributable to deoxyribonucleic acid. Swiss Webster mice, 4-5 weeks of age, weighing 24-26 g with 4 X 10(6) ascites sarcoma-180 cells when injected with 3 X 7.0 micronC of tritiated thymidine on day 5 of the tumor implant, show specific labeling on the plasma membrane surface. The photopositive silver grain distribution in both the light and electron microscope autoradiograms when followed from the nucleus outwards show a distinct peak over the nucleus and the plasma membrane. The quantity and origin and role of this surface-associated deoxyribonucleic acid is not clear.


1978 ◽  
Vol 77 (2) ◽  
pp. 323-328 ◽  
Author(s):  
WW Franke ◽  
C Grund ◽  
E Schmid ◽  
E Mandelkow

In cultured cells of the rat kangaroo PtK2 line, veils of the cell surface were observed which consisted of only plasma membrane and paracrystalline arrays of membrane-associated particles sandwiched in between. These membrane-to-membrane cross-bridging 9-to 11-nm wide particles were somewhat coumellar-shaped and were arranged on a hexagonal lattice with an interparticle distance of 16nm. At higher magnification, they revealed an unstained core, thus suggesting a ringlike substructure. Similar arrays of paracrystal-containing veils, which were rather variable in size and frequency, were also observed in other cultured cells. It is hypothesized that these paracrystals represent protein macromolecular complexes associated with the inner plasma membrane surface which crystallize when plasma membranes come into close intracellular contact and other components of the subsurface network are removed.


Author(s):  
S. V. Zubova ◽  
D. S. Kabanov ◽  
A. Yu. Ivanov ◽  
E. V. Voloshina ◽  
I. I. Proskuryakov ◽  
...  

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