A case-control study on food intake of patients with recurrent aphthous stomatitis

Author(s):  
Masayuki Ogura ◽  
Tatsuo Yamamoto ◽  
Manabu Morita ◽  
Tatsuo Watanabe
2018 ◽  
Vol 126 (6) ◽  
pp. 485-492 ◽  
Author(s):  
Petra Borilova Linhartova ◽  
Julius Janos ◽  
Simona Slezakova ◽  
Jirina Bartova ◽  
Jitka Petanova ◽  
...  

2021 ◽  
Vol 35 ◽  
pp. 205873842110644
Author(s):  
Shereen A Baioumy ◽  
Shaimaa H Fouad ◽  
Shaimaa A Abdalgeleel ◽  
Ahmed A Baiomy ◽  
Dina E Sallam ◽  
...  

Objectives: Dysregulation of the immune response appears to play a significant role in recurrent aphthous stomatitis (RAS) development. The main objective of this case–control study is to investigate the blood levels of mannose-binding lectin (MBL) and the frequency of the MBL2 gene (gly54asp) polymorphism in RAS patients, including 40 RAS patients and 40 healthy controls. Methods: Serum MBL levels were determined by ELISA, while the PCR-restriction fragment length polymorphism was used in MBL2 genotyping. Results: The median serum MBL level was significantly lower in the RAS group than in the control group (975 ng/mL (545–1320) vs. 1760 ng/mL (1254–2134); p≤ 0.001). The MBL levels were significantly lower in the BB genotype, whereas they were significantly higher in the wild type AA with a median of 525 and 1340 ng/mL, respectively ( p =0.005). The B allele was expressed in significantly higher percentages of RAS patients than in controls. There was no significant association between MBL serum levels ( p=0.685) or MBL2 codon 54 genotypes ( p=0.382) with the type of ulcers. Conclusion: There was an association between low MBL serum levels and the variant allele B of the MBL2 (gly54asp) gene, and the susceptibility to RAS. As a result, potential novel therapeutic options for RAS patients with MBL deficiency should be investigated.


2019 ◽  
Vol 118 (3) ◽  
pp. 664-670 ◽  
Author(s):  
Kuan-Chou Lin ◽  
Lo Lin Tsai ◽  
Edward Chengchuan KO ◽  
Kevin Sheng-Po Yuan ◽  
Szu-Yuan Wu

2009 ◽  
Vol 91 (3) ◽  
pp. 812-818 ◽  
Author(s):  
Jaime Mendiola ◽  
Alberto M. Torres-Cantero ◽  
José M. Moreno-Grau ◽  
Jorge Ten ◽  
Manuela Roca ◽  
...  

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