Bovine luteal blood flow: basic mechanism and clinical relevance

2013 ◽  
Vol 25 (1) ◽  
pp. 71 ◽  
Author(s):  
Heinrich Bollwein ◽  
Johannes Lüttgenau ◽  
Kathrin Herzog
Keyword(s):  
Blood Flow ◽  
Doppler Sonography ◽  
Decisive Role ◽  
Basic Mechanism ◽  
Colour Doppler Sonography ◽  
Plasma Progesterone ◽  
Luteal Function ◽  
Additional Information ◽  
Interindividual Variations

The introduction of transrectal colour Doppler sonography (CDS) has allowed the evaluation of luteal blood flow (LBF) in cows. Because appropriate angiogenesis plays a decisive role in the functioning of the corpus luteum (CL), studies on LBF may provide valuable information about the physiology and pathophysiology of the CL. Studies on cyclic cows have shown that progesterone concentrations in blood plasma can be more reliably predicted by LBF than by luteal size (LS), especially during the regression phase of the CL. In contrast with non-pregnant cows, a significant increase in LBF is seen in pregnant cows during the third week after insemination. However, because there are high interindividual variations in LBF between animals, LBF is not useful for the early diagnosis of pregnancy. Determination of LBF is more sensitive than LS for detecting the effects of acute systemic inflammation and exogenous hormones on the CL. Cows with low progesterone levels have smaller CL during the mid-luteal phase, but LBF related to LS did not differ between cows with low and high progesterone levels. In conclusion, LBF determined by CDS provides additional information about luteal function compared with LS and plasma progesterone concentrations, but its role concerning fertility in the cow is yet to be clarified.

scholarly journals Doppler ultrasound in pregnancy – quality requirements of DEGUM and clinical application (part 2)

2021 ◽  
Author(s):  
Renaldo Faber ◽  
Kai-Sven Heling ◽  
Horst Steiner ◽  
Ulrich Gembruch
Keyword(s):  
Blood Flow ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Umbilical Artery ◽  
Prophylactic Treatment ◽  
Doppler Sonography ◽  
First Trimester ◽  
Ductus Venosus ◽  
Fetal Diagnosis

AbstractThis second part on Doppler sonography in prenatal medicine and obstetrics reviews its clinical applications. While this has not become the initially anticipated screening tool, it is used for the diagnosis and surveillance of a variety of fetal pathologies. For example, the sonography-based determination of uterine artery blood flow indices is an important parameter for the first trimester multimodal preeclampsia risk assessment, increasing accuracy and providing indication for the prophylactic treatment with aspirin. It also has significant implications for the diagnosis and surveillance of growth-restricted fetuses in the second and third trimesters through Doppler-sonographic analysis of umbilical artery, middle cerebral artery and ductus venosus. Here, especially the hemodynamics of the ductus venosus provides a critical criterium for birth management of severe, early-onset FGR before 34 + 0 weeks of gestation. Further, determination of maximum blood flow velocity of the middle cerebral artery is a central parameter in fetal diagnosis of anemia which has been significantly improved by this analysis. However, it is important to note that the mentioned improvements can only be achieved through highest methodological quality. Importantly, all these analyses are also applied to twins and higher order multiples. Here, for the differential diagnosis of specific complications such as TTTS, TAPS and TRAP, the application of Doppler sonography has become indispensable. To conclude, the successful application of Doppler sonography requires both exact methodology and precise pathophysiological interpretation of the data.

Investigation of mammary blood flow changes by transrectal colour Doppler sonography in anEscherichia colimastitis model

2010 ◽  
Vol 77 (2) ◽  
pp. 205-212 ◽  
Author(s):  
André Potapow ◽  
Carola Sauter-Louis ◽  
Sandra Schmauder ◽  
Jutta Friker ◽  
Cordula Poulsen Nautrup ◽  
...  
Keyword(s):  
Blood Flow ◽  
Doppler Sonography ◽  
Early Stage ◽  
Preliminary Investigation ◽  
Intraclass Correlation ◽  
Colour Doppler Sonography ◽  
Colour Doppler ◽  
Flow Changes ◽  
The Difference ◽  
The Right

The objectives of this preliminary investigation were to evaluate the feasibility of transrectal colour Doppler sonography (TCDS) for determining blood flow of the pudendoepigastric trunk in cows with experimentally inducedEscherichia coliMastitis. Five primiparous Holstein dairy cows, 4–6 months after calving, were examined in two trials. All monitored udder quarters were initially clinically healthy, somatic cell count (SCC) was <50 000 cells/ml and bacteriologically negative. The blood flow of the left and the right pudendoepigastric trunk was described by the blood flow volume (BFV). In the methodological part of the study, the intra-observer precision of the method was evaluated. The coefficients of variation of the BFV were 7·1% for the left and 9·4% for the right pudendoepigastric trunk. The intraclass correlation coefficients of the BFV were 0·99 (P<0·001) for the left and 0·75 (P=0·004) for the right vessel. BFV did not differ significantly between the left and the right side nor between pre- and post-milking nor between oestrus and dioestrus. In the experimental part of the study, significant differences of increasing BFV between 0 and 12 h p.i. (post infectionem) (P=0·043) and decreasing BFV between 12 and 24 h p.i. (P=0·043) were discovered for the pudendoepigastric trunk of the infected right side. In the left-right (control-infection) comparison a significant increase of the right BFV was observed at 12 h p.i. (P=0·043). The difference of an increasing SCC correlated positively with the difference of an increasing BFV between 0 and 12 h p.i. (Spearman's ρ=1·00;P=0·043) for the right infected side. It was shown that TCDS is a reproducible technique for investigating pathological mammary blood flow changes at an early stage of acute mastitis.

Uterine perfusion in patients with MMP2 gene polymorphisms

GYNECOLOGY ◽  
2021 ◽  
Vol 23 (5) ◽  
pp. 413-420
Author(s):  
Tatiana E. Filipenkova ◽  
Liia N. Shcherbakova ◽  
Aleksandr V. Balatskiy ◽  
Larisa M. Samokhodskaya ◽  
Olga B. Panina
Keyword(s):  
Blood Flow ◽  
Pulsatility Index ◽  
Qualitative Assessment ◽  
Control Group ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Additional Information ◽  
Uterine Perfusion ◽  
Definition Of

Aim. To investigate the effect of allelic polymorphisms of the MMP2 gene on uterine perfusion in patients planning pregnancy. Materials and methods. 95 women planning pregnancy were examined. The patients underwent clinical and laboratory examination, analysis of single nucleotide polymorphisms rs2285052 and rs243865 of the MMP2 gene, ultrasound examination on days 1825 of the menstrual cycle with an assessment of the pulsatility index of blood flow of the uterine vessels and a qualitative assessment of endometrial and subendometrial perfusion. Depending on the genotype, the patients were divided into 3 groups: first with haplotype rs2285052(A)rs243865(T), second with haplotype rs2285052(A)rs243865(С), and a third control group with rs2285052(С/С)rs243865(С/С) genotype. Results. Decreased perfusion in the subendometrial zone was found in 40.6, 44.4 and 19.4% of patients in the 1, 2 and 3 groups, respectively; decreased perfusion of endometrium in 68.8, 55.6 and 36.1% of patients in the 1, 2 and 3 groups, respectively. Spiral arteries were not visualized in 28.1, 14.8 and 11.1% of patients in the 1, 2 and 3 groups, respectively. No statistical differences were found in the pulsatility index of uterine blood flow depending on the genotype. Conclusion. In patients with the A rs2285052 and T rs243865 alleles of the MMP2 gene poor vascular patterns of the endometrium and subendometrial zone of the uterus were statistically significantly more frequent, which can lead to infertility. These associations are more pronounced for the rs2285052 polymorphism. The simultaneous determination of the rs2285052 and rs243865 polymorphisms does not provide additional information compared to the definition of rs2285052 alone.

Relationship of luteal blood flow and corpus luteum function in pseudopregnant rats.

1979 ◽  
Vol 237 (1) ◽  
pp. E30
Author(s):  
C Y Pang ◽  
H R Behrman
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Corpus Luteum ◽  
Tissue Blood Flow ◽  
Corpora Lutea ◽  
Plasma Progesterone ◽  
Luteal Regression ◽  
Luteal Function ◽  
Arterial Blood ◽  
Relationship Of

An experiment was conducted to examine whether blood flow to corpora lutea may regulate luteal function as judged from plasma levels of progesterone (P) in mature pseudopregnant rats. 141Ce-labeled microspheres (14.1 +/- 0.8 micrometer diam) were used to measure cardiac output and organ and tissue blood flow in rats on days 6, 8, 10, and 12 of pseudopregnancy and in proestrus following luteal regression. The mean arterial blood pressure and cardiac output were similar among all groups of rats. Although a significant (P less than 0.05) decrease in plasma P was observed in rats on day 12 of pseudopregnancy, no change in luteal blood flow or distribution of ovarian blood flow to the corpora lutea was seen at this stage of pseudopregnancy when compared to day 8 or 10 of pseudopregnancy. However, a significant decrease (P less than 0.05) in luteal blood flow was seen in proestrous rats. Because a decrease in plasma progesterone preceded the decrease in luteal blood flow, it was concluded that physiological luteal regression may not be initiated by a reduction of blood flow to the corpus luteum.

scholarly journals Is it always DVT? evaluation of leg swelling with color Doppler Sonography

2016 ◽  
Vol 11 (3) ◽  
Author(s):  
Sadaf Batool ◽  
Asim Shaukat ◽  
Khawaja Khurshid Ahmad ◽  
Tahir Qadeer Khan ◽  
Afshan Qureshi ◽  
...  
Keyword(s):  
Doppler Ultrasonography ◽  
Doppler Sonography ◽  
Color Doppler ◽  
Duplex Ultrasound ◽  
Lower Limbs ◽  
Colour Doppler Sonography ◽  
Vein Thrombosis ◽  
Duplex Imaging ◽  
Deep Vein

Objective: The aim of this study was to assess the value of duplex ultrasound examination in establishing diagnosis in swollen lower limbs. Setting: This study was conducted at the Department of Diagnostic radiology Mayo hospital Lahore. Method: 50 consecutive patients presenting with leg swelling, submitted for colour Doppler sonography of the lower extremities were examined for deep vein thrombosis (DVT). Results: 46% of the patients were detected as having DVT , when examined through Doppler Ultrasonography. While 28% of the patients were not having any pathology in the limb.26% of the patients were having pathology other than DVT. Conclusion: The veins of the calf muscles are a common site of acute DVT and a source of pulmonary embolism. They should always be investigated in patients with leg swelling. Complete venous evaluation with duplex imaging can be very helpful in determination of underlying cause of the swelling.

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