107 Anti-Müllerian hormone plasma concentration in alpacas as a predictor of their ovarian reserve

2022 ◽  
Vol 34 (2) ◽  
pp. 290
Author(s):  
R. Céliz ◽  
E. Alvarado ◽  
A. Gallegos-Cárdenas
Keyword(s):  
Plasma Concentration ◽  
Ovarian Reserve

The influence of sex steroids in commercial fish meals and fish diets on plasma concentration of estrogens and vitellogenin in cultured Siberian sturgeonAcipenser baeri

1989 ◽  
Vol 2 (3) ◽  
pp. 161-168 ◽  
Author(s):  
Catherine Pelissero ◽  
Blandine Cuisset ◽  
Françoise Le Menn
Keyword(s):  
Plasma Concentration ◽  
Sex Steroids ◽  
Commercial Fish ◽  
Fish Diets

Bispectral index-guided titration of sevoflurane during on-pump cardiac surgery reduces sevoflurane plasma concentration and vasopressor requirements

2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
R. Nitzschke ◽  
J. Wilgusch ◽  
S. Haas ◽  
C. Trepte ◽  
A.E. Goetz ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Plasma Concentration ◽  
Bispectral Index

Elevated Levels of Prothrombin Activation Fragment 1+2 in Plasma from Patients with Heterozygous Arg506 to Gin Mutation in the Factor V Gene (APC-Resistance) and/or Inherited Protein S Deficiency

1996 ◽  
Vol 75 (02) ◽  
pp. 270-274 ◽  
Author(s):  
Benget Zöller ◽  
Johan Holm ◽  
Peter Svensson ◽  
Björn Dahlbäck
Keyword(s):  
Plasma Concentration ◽  
Protein C ◽  
Protein S ◽  
Factor V ◽  
Protein S Deficiency ◽  
Apc Resistance ◽  
S Deficiency ◽  
Increased Risk ◽  
Factor V Gene ◽  
V Gene

SummaryInherited resistance to activated protein C (APC-resistance), caused by a point mutation in the factor V gene leading to replacement of Arg(R)506 with a Gin (Q), and inherited protein S deficiency are associated with functional impairment of the protein C anticoagulant system, yielding lifelong hypercoagulability and increased risk of thrombosis. APC-resistance is often an additional genetic risk factor in thrombosis-prone protein S deficient families. The plasma concentration of prothrombin fragment 1+2 (F1+2), which is a marker of hyper-coagulable states, was measured in 205 members of 34 thrombosis-prone families harbouring the Arg506 to Gin mutation (APC-resistance) and/or inherited protein S deficiency. The plasma concentration of F1+2 was significantly higher both in 38 individuals carrying the FV:Q506 mutation in heterozygous state (1.7 ± 0.7 nM; mean ± SD) and in 48 protein S deficient cases (1.9 ± 0.9 nM), than in 100 unaffected relatives (1.3 ±0.5 nM). Warfarin therapy decreased the F1+2 levels, even in those four patients who had combined defects (0.5 ± 0.3 nM). Our results agree with the hypothesis that individuals with APC-resistance or protein S deficiency have an imbalance between pro- and anti-coagulant forces leading to increased thrombin generation and a hypercoagulable state.

Intoxication with Phenprocoumon (Marcoumar) Pharmacokinetics and Side Effects

1969 ◽  
Vol 21 (02) ◽  
pp. 320-324 ◽  
Author(s):  
K Seiler ◽  
F Duckert
Keyword(s):  
Plasma Concentration ◽  
Side Effects ◽  
Half Life ◽  
Plasma Proteins ◽  
Repeated Administration ◽  
High Plasma ◽  
Vitamin K1 ◽  
Clotting Factors ◽  
Therapeutic Concentration ◽  
High Plasma Concentration

SummaryA case of severe Marcoumar intoxication is described. Eleven hours after the intake a plasma concentration of 15.75 µg/ml was found which corresponds approximately to the 5-fold therapeutic concentration. Repeated administration of vitamin K1 made it possible to avoid extreme lowering of the activity of the clotting factors II, VII and X and to prevent bleeding. Side effects were not observed. The biologic half-life of Phenprocoumon has been found to be shortened at high plasma concentration (3.7 instead of 5.9 days). It is probable that in extreme concentration the drug is less strongly bound to the plasma proteins.

A Common Thrombomodulin Amino Acid Dimorphism Is Associated with Myocardial Infarction

1997 ◽  
Vol 77 (02) ◽  
pp. 248-251 ◽  
Author(s):  
Lena Norlund ◽  
Johan Holm ◽  
Bengt Zöller ◽  
Ann-Kristin Öhlin
Keyword(s):  
Myocardial Infarction ◽  
Amino Acid ◽  
Plasma Concentration ◽  
Acute Coronary Syndromes ◽  
Protein C ◽  
Integral Membrane Protein ◽  
Control Group ◽  
Healthy Controls ◽  
Coronary Syndromes ◽  
Premature Myocardial Infarction

SummaryEndothelial dysfunction and haemostatic imbalance are believed to be important aetiological factors in the development of acute coronary syndromes. Thrombomodulin (TM) is an integral membrane protein crucial for normal endothelial function and activation of the protein C anticoagulant pathway. We have investigated the importance of a common C/T dimorphism in the TM gene (nucleotide 1418) for development of premature myocardial infarction (MI). The C/T dimorphism predicts an Ala455 to Val replacement in the sixth EGF-like domain of TM. The dimorphism was investigated in 97 MI survivors and 159 healthy controls. The C allele was significantly more frequent among patients than controls (p = 0.035). The allele frequency for the C allele was 0.82 in the patients and 0.72 in the control group. The plasma concentration of TM was investigated among healthy controls but was not related to the C/T dimorphism. In conclusion, the association of the C allele with premature MI, suggests that the TM gene and the C/T dimorphism may be aetiological factors involved in the pathogenesis of MI. Possibly, the Ala455 to Val replacement may affect the function of the TM molecule and the activation of the protein C anticoagulant pathway.

Serum AMH concentration has limited prognostic value for the density of primordial follicles questioning AMH as a parameter for the real ovarian reserve

2018 ◽  
Author(s):  
J Liebenthron ◽  
J Reinsberg ◽  
R Fimmers ◽  
N Sänger ◽  
K van der Ven ◽  
...  
Keyword(s):  
Ovarian Reserve ◽  
Prognostic Value ◽  
Primordial Follicles ◽  
The Real

PLACENTAL TRANSFER OF INSULIN-131I IN GUINEA PIGS IMMUNIZED AGAINST INSULIN

1966 ◽  
Vol 52 (2) ◽  
pp. 276-291 ◽  
Author(s):  
Jan I. Thorell
Keyword(s):  
Plasma Concentration ◽  
Guinea Pigs ◽  
Placental Transfer ◽  
Maternal Plasma ◽  
Insulin Antibodies ◽  
Insulin Antibody

ABSTRACT The placenta is considered to be impermeable or only slightly permeable to insulin. Insulin antibodies are transferred from mother to foetus in man and in guinea pigs. The passage of insulin-131I from mother to foetus was studied in guinea pigs with and without antibodies against insulin. Antibody-bound insulin-131I was recovered in plasma from foetuses of immunized pregnant guinea pigs, at intervals of more than 5 hours after the injection of insulin-131I to the mother. The foetal levels of insulin-131I were rather low, the highest recorded value being 27% of the maternal plasma concentration. This peak was reached 32 hours after the injection. No insulin-131I was found in the foetuses of non-immunized guinea pigs.

Thyroid hormone-catecholamine interrelationships during exposure to cold

1981 ◽  
Vol 97 (1) ◽  
pp. 91-97 ◽  
Author(s):  
H. Storm ◽  
C. van Hardeveld ◽  
A. A. H. Kassenaar
Keyword(s):  
Nervous System ◽  
Plasma Concentration ◽  
Thyroid Hormone ◽  
Sympathetic Nervous System ◽  
Plasma Levels ◽  
Surgical Procedure ◽  
Exposure To Cold ◽  
Basal Plasma ◽  
Sympathetic Nervous

Abstract. Basal plasma levels for adrenalin (A), noradrenalin (NA), l-triiodothyronine (T3), and l-thyroxine (T4) were determined in rats with a chronically inserted catheter. The experiments described in this report were started 3 days after the surgical procedure when T3 and T4 levels had returned to normal. Basal levels for the catecholamines were reached already 4 h after the operation. The T3/T4 ratio in plasma was significantly increased after 3, 7, and 14 days in rats kept at 4°C and the same holds for the iodide in the 24-h urine after 7 and 14 days at 4°C. The venous NA plasma concentration was increased 6- to 12-fold during the same period of exposure to cold, whereas the A concentration remained at the basal level. During infusion of NA at 23°C the T3/T4 ratio in plasma was significantly increased after 7 days compared to pair-fed controls, and the same holds for the iodide excretion in the 24-h urine. This paper presents further evidence for a role of the sympathetic nervous system on T4 metabolism in rats at resting conditions.

Evidence for preserved ovarian reserve in transgender men receiving testosterone therapy: Anti-mullerian hormone serum levels decrease modestly after one year of treatment

2019 ◽  
Author(s):  
Iris Yaish ◽  
Gad Malinger ◽  
Foad Azem ◽  
Yael Sofer ◽  
Nechama Golani ◽  
...  
Keyword(s):  
Ovarian Reserve ◽  
Serum Levels ◽  
Testosterone Therapy ◽  
One Year ◽  
Transgender Men

Long-term effects of childhood cancer treatment on hormonal and ultrasound markers of ovarian reserve

2019 ◽  
Author(s):  
van den Berg MH ◽  
Overbeek A ◽  
Lambalk CB ◽  
Kaspers GJL ◽  
Bresters D ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Childhood Cancer ◽  
Ovarian Reserve ◽  
Long Term Effects
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