scholarly journals The Forkhead Transcription Factor FOXO4 Induces the Down-regulation of Hypoxia-inducible Factor 1α by a von Hippel-Lindau Protein-independent Mechanism

2003 ◽  
Vol 278 (32) ◽  
pp. 30125-30135 ◽  
Author(s):  
Tracy Tzu-Ling Tang ◽  
Laurence A. Lasky
Keyword(s):  
Transcription Factor ◽  
Hypoxia Inducible Factor ◽  
Forkhead Transcription Factor ◽  
Down Regulation ◽  
Von Hippel Lindau ◽  
Hypoxia Inducible Factor 1Α ◽  
Independent Mechanism

scholarly journals Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Xianyi Meng ◽  
Bettina Grötsch ◽  
Yubin Luo ◽  
Karl Xaver Knaup ◽  
Michael Sean Wiesener ◽  
...  
Keyword(s):  
Transcription Factor ◽  
B Cells ◽  
Autoimmune Disease ◽  
Hypoxia Inducible Factor ◽  
Hypoxia Inducible Factor 1Α

scholarly journals Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories

MedChemComm ◽  
2017 ◽  
Vol 8 (1) ◽  
pp. 21-52 ◽  
Author(s):  
Anthony R. Martin ◽  
Cyril Ronco ◽  
Luc Demange ◽  
Rachid Benhida
Keyword(s):  
Stem Cells ◽  
Transcription Factor ◽  
Cancer Stem Cells ◽  
Hypoxia Inducible Factor ◽  
Large Set ◽  
Down Regulation ◽  
Self Renewal ◽  
Hypoxia Inducible Factor 1 ◽  
Success Stories ◽  
Tumour Vascularization

In cancers, hypoxia inducible factor 1 (HIF-1) is an over-expressed transcription factor, which regulates a large set of genes involved in tumour vascularization, metastases, and cancer stem cells (CSCs) formation and self-renewal.

Abstract 383: Down-regulation of tumoral Hypoxia-Inducible Factor-1α expression in OVCAR-3 tumors by albendazole

2010 ◽  
Author(s):  
Mohammad H. Pourgholami ◽  
Zhao Yan Cai ◽  
Samina Badar ◽  
Marianne Poruchynsky ◽  
David Lawson Morris
Keyword(s):  
Hypoxia Inducible Factor ◽  
Down Regulation ◽  
Hypoxia Inducible Factor 1Α ◽  
Tumoral Hypoxia
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