Innovation articles.

2021 ◽  
pp. 85-105
Author(s):  
Rhonda Smith

Abstract In this chapter, ten entrepreneurs who have led the establishment of their companies and are vigorously leading their development, share their motivations and insights. Hear from those who now lead international well-established enterprises to those who are emerging from the start-up or pilot phase and continue to work towards that first significant grant, or angel investment, that will enable them to take the first step to scale up.

Author(s):  
Gilles Duruflé ◽  
Thomas Hellmann ◽  
Karen Wilson

This chapter examines the challenge for entrepreneurial companies of going beyond the start-up phase and growing into large successful companies. We examine the long-term financing of these so-called scale-up companies, focusing on the United States, Europe, and Canada. The chapter first provides a conceptual framework for understanding the challenges of financing scale-ups. It emphasizes the need for investors with deep pockets, for smart money, for investor networks, and for patient money. It then shows some data about the various aspects of financing scale-ups in the United States, Europe, and Canada, showing how Europe and Canada are lagging behind the US relatively more at the scale-up than the start-up stage. Finally, the chapter raises the question of long-term public policies for supporting the creation of a better scale-up environment.


2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Seedhabadee Ganeshan ◽  
Seon Hwa Kim ◽  
Vladimir Vujanovic

AbstractThe benefit of microorganisms to humans, animals, insects and plants is increasingly recognized, with intensified microbial endophytes research indicative of this realization. In the agriculture industry, the benefits are tremendous to move towards sustainable crop production and minimize or circumvent the use of chemical fertilizers and pesticides. The research leading to the identification of potential plant endophytes is long and arduous and for many researchers the challenge is ultimately in scale-up production. While many of the larger agriculture and food industries have their own scale-up and manufacturing facilities, for many in academia and start-up companies the next steps towards production have been a stumbling block due to lack of information and understanding of the processes involved in scale-up fermentation. This review provides an overview of the fermentation process from shake flask cultures to scale-up and the manufacturing steps involved such as process development optimization (PDO), process hazard analysis (PHA), pre-, in- and post-production (PIP) challenges and finally the preparation of a technology transfer package (TTP) to transition the PDO to manufacturing. The focus is on submerged liquid fermentation (SLF) and plant endophytes production by providing original examples of fungal and bacterial endophytes, plant growth promoting Penicillium sp. and Streptomyces sp. bioinoculants, respectively. We also discuss the concepts, challenges and future perspectives of the scale-up microbial endophyte process technology based on the industrial and biosafety research platform for advancing a massive production of next-generation biologicals in bioreactors.


2021 ◽  
Vol 11 (4) ◽  
pp. 1-54
Author(s):  
Mohammad Rishad Faridi ◽  
Saloni Sinha

Learning outcomes Appendix 1: Comic Frames A At the end of the case study discussion, students will able to as follows: Explain various growth strategies as a potential unicorn with the exponential growth mindset rather than linear growth mindset through adaptation of Massive Transformative Purpose (MTP) and Moonshot Thinking (MT). Demonstrate innovative and creative plans and ideas, with the ability to scale up in the circular economy. Review and summarize the power of Collaborative Innovation (CI). Compare and contrast different ways in dealing with Hedgehog and Fox style of leadership into the business. Appendix 2: Comic Frames B At the end of the case study discussion, students will able to as follows: Act with a growth strategy as a potential unicorn with the exponential growth mindset rather than linear growth mindset through adaptation of MTP and MT. Simulate innovative and creative plans and ideas, with the ability to scale up in the circular economy. Assess and leverage the power of CI. Decide and differentiate in dealing with Hedgehog and Fox style of leadership into the business. Case overview/synopsis Ankit Tripathi, was a compassionate 22-year-old, the typical lad from New Delhi, India, who seemed driven to change the world. His elder brother Atul Tripathi, a young, creative 25-year-old, was sat there next to him, beaming with pride and gratitude. Both brothers, being mechanical engineering graduates, had experienced the advancement of technology at the cost of Mother Earth. It pained them no end. It was the reason that Atul had refused to serve as an engineer in a government institution after graduating. The parents were shocked when Ankit followed suit. The brothers were poles apart in their personality and temperament, and it was rare to see them agree on anything in this way. Yet, they agreed to disagree with their parents and ventured into becoming entrepreneurs with a purpose and passion to salvage the environment. They had a vision, but without a proper roadmap, it would certainly be a tough game. Nevertheless, they boldly embarked upon their journey and established their start-up “Uneako” in 2019. “Uneako” was a calculated risk, taking into account family resistance (parents’ attitude/perception), personal conflicts (psychological), financial limitations (resources), shallow expertise (professionalism), social concern acceptability and low awareness (environment), government regulations (legalities/approvals), conflicts between brothers (personality issues), etc. Being from a nonbusiness family, the brothers had defied the wave of obstacles and challenges in daring to start their own business, putting at stake the hard-earned money of their father, Satendra Tripathi. Amidst so much social mockery, would Atul and Ankit succumb and become a laughing stock or would they find something that they could live and die for? Complexity Academic Level Appendix 1: Comic Frames A: This case has been particularly focused on undergraduate level students pursuing business or commerce programs. Especially those studying core courses, for example, entrepreneurial and strategic management. Appendix 2: Comic Frames B: This case has been particularly focused postgraduate-early stage or higher level students pursuing business or commerce programs. Particularly those specializing in entrepreneurial and strategic management courses. Also, can be taught in the entrepreneurial or start-up workshops. Supplementary materials www.pewresearch.org/topics/generation-z/ Paulynice. J.P., (2019) “From Idea to Reality: An Entrepreneur’s Guide to Meaningful Business Growth” Paulynice Consulting Group. Hardy.D., (2015) “The Entrepreneur Roller Coaster: It’s Your Turn to Join The Ride” Success Publishers. Wadhwa.V., Amla.I., Salkever.A., (2020) “From Incremental to Exponential” Berrett-Koehler Publishers. Sustainable Entrepreneurship: Business Success through Sustainability edited by Christina Weidinger, Franz Fischler, René Schmidpeter, Springer 2014. Teaching notes are available for educators only. Subject code CSS 3: Entrepreneurship.


2019 ◽  
Vol 18 ◽  
pp. 44
Author(s):  
Anita Cassidy

<p>In 2015 the City of Burlington developed a new 2015-2040 Strategic Plan: <em>Grow Bold, </em>which tasked Burlington Economic Development Corporation (BEDC) with supporting the start up and scale up of companies and making Burlington a start up destination. This article will outline the process that BEDC went through to better understand the local innovation ecosystem and the role that BEDC could play in supporting it. This process resulted in BEDC going from no role in supporting companies to start and grow to launching, TechPlace, Burlington’s new innovation Centre in 2017, which supported over 4,000 visitors in their entrepreneurial journey in year one of operations. </p><p><strong>Keywords: </strong>Innovation, Entrepreneurship, Startups, Job Creation, Startup Support, Innovation Centre</p>


2018 ◽  
Vol 8 (3) ◽  
pp. 1-27
Author(s):  
Ammani Pagadala ◽  
Rajiv Gupta

Subject area Strategy Study level/applicability Strategic Management course in an undergraduate programme. Case overview PKC Laundries started a technology-driven laundry service that would be just a click away for their customers and would provide a quick and satisfying cost-effective solution to the customers’ laundry needs. The business, conceived as a start-up, was based on the asset-light aggregation model which used existing vendors to provide the service. The business has been running for almost two years now but has encountered certain operational challenges of vendor management and in generating sufficient operating profits. At this juncture, the question that is bothering the owners is would it be right if PKC went in for backward integration by investing in an automatic laundry plant to manage the risk of dependency on their vendors or should they strengthen and scale-up the present business model? The owners seem to be in a muddle about their strengths and weaknesses and the foreseeable opportunities and threats and going forward what sort of challenges should they prepare themselves for? This case requires the reader to understand the scenario in which a small and medium enterprise (SME) operates within its micro and macro environment. It then makes the reader think and critically analyse the dilemma the young entrepreneurs are facing and identify the problems and possible strategies to overcome these problems. The case highlights the challenges faced by PKC as an aggregator business and the scope of what PKC can do in the future to strengthen its position. It also explores various marketing management issues such as segmenting, targeting and positioning. The case also helps in understanding strategic management issues such as analysis and formulation and implementation of the strategy. Expected learning outcomes The expected learning outcomes are as follows: To understand the micro and macro environmental factors affecting a firm; to understand the issues involved in formulating and implementing a strategy; to understand the challenges faced by a start-up (both operational and for scaling up); and to understand the strategies adopted by the company to develop their business. Supplementary materials Teaching Notes are available for educators only. Please contact your library to gain login details or email [email protected] to request teaching notes. Subject code CSS 11: Strategy.


2019 ◽  
Vol 31 (3) ◽  
pp. 1525-1533 ◽  
Author(s):  
Bahar Aslanbay Guler ◽  
Irem Deniz ◽  
Zeliha Demirel ◽  
Suphi S. Oncel ◽  
Esra Imamoglu

2019 ◽  
Vol 69 (686) ◽  
pp. e605-e611 ◽  
Author(s):  
Helen P Booth ◽  
Arlene M Gallagher ◽  
David Mullett ◽  
Lucy Carty ◽  
Shivani Padmanabhan ◽  
...  

BackgroundQuality improvement (QI) is a priority for general practice, and GPs are expected to participate in and provide evidence of QI activity. There is growing interest in harnessing the potential of electronic health records (EHR) to improve patient care by supporting practices to find cases that could benefit from a medicines review.AimTo develop scalable and reproducible prescribing safety reports using patient-level EHR data.Design and settingUK general practices that contribute de-identified patient data to the Clinical Practice Research Datalink (CPRD).MethodA scoping phase used stakeholder consultations to identify primary care QI needs and potential indicators. QI reports containing real data were sent to 12 pilot practices that used Vision GP software and had expressed interest. The scale-up phase involved automating production and distribution of reports to all contributing practices that used both Vision and EMIS software systems. Benchmarking reports with patient-level case review lists for two prescribing safety indicators were sent to 457 practices in December 2017 following the initial scale-up (Figure 2).ResultsTwo indicators were selected from the Royal College of General Practitioners Patient Safety Toolkit following stakeholder consultations for the pilot phase involving 12 GP practices. Pilot phase interviews showed that reports were used to review individual patient care, implement wider QI actions in the practice, and for appraisal and revalidation.ConclusionElectronic health record data can be used to provide standardised, reproducible reports that can be delivered at scale with minimal resource requirements. These can be used in a national QI initiative that impacts directly on patient care.


2014 ◽  
pp. 107-143
Author(s):  
Gustavo Crespi ◽  
Eduardo Fernández-Arias ◽  
Ernesto Stein
Keyword(s):  
Scale Up ◽  

With the rise of E-Cinemas, Indians are watching movies like never before. As per data released by Statista, a media research agency, it is believed that nearly 20,000 movies hit the theatres every year, making India the largest movie producer worldwide. Movies are a way of social bonding for families given the multiplex culture in Urban areas. With the proliferation of technology and the reach of 4G, there is also the convenience of buying tickets online. Gone are the days of long queues and nonavailability of information regarding show timings. The emergence of online ticketing platforms have simplified the hassles of buying tickets through counters and increased audience showing up in theatres. The present study makes an attempt to study the rise of ‘Book My Show’, an online ticketing company who pioneered the model of selling movie tickets online during the early 2000s when Indian laws were not so favourable. Being an innovative start up, the company is a game-changer who transformed the movie experience of cinema goers in India. It has touched the prestigious $ 1 billion valuation recently. The paper investigates the rise of the company to its present state by a thorough study of all the aspects of business. Through an indepth secondary data reference the study analyses the factors that contributed to the rise of the company. The study is important as it explains techno-preneurship as a medium of disrupting traditional markets. The current study is organised as follows: Part I explores the business model of the company, how it negotiated its presence in the market and some nuances related to strategy which propelled its growth. Part II explores the dimensions of digital media that helped the company to scale up exponentially.


2020 ◽  
Vol 8 (1) ◽  
pp. 155-196
Author(s):  
JOAQUÍN GARCIA-TAPIAL ◽  
MANUEL ALEJANDRO CARDENETE
Keyword(s):  
Scale Up ◽  

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