scholarly journals Effect of the protein content of the diet on the vitamin B12 status in rats

1974 ◽  
Vol 31 (2) ◽  
pp. 219-225
Author(s):  
V. S. Jathar ◽  
R. S. Satoskar ◽  
B. M. Mehta ◽  
D. V. Rege
Keyword(s):  
Vitamin B12 ◽  
Protein Content ◽  
Serum Protein ◽  
Vitamin B ◽  
Tissue Binding ◽  
Fresh Weight ◽  
Protein Starvation ◽  
Nitrogen Contents ◽  
Total Tissue

1. The effects of the protein content of the diet on the vitamin B12 concentration of serum and of various tissues were studied in rats by means of microbiological and radioisotopic techniques.2. Protein starvation reduced tissue weights and nitrogen contents, serum protein concentrations and haemoglobin values.3. The vitamin B12 contents of the serum and of several organs and tissues were greater in the protein-starved animals for reasons that remain unexplained.4. The retention of radioactive cyanocobalamin per g fresh weight was significantly greater in liver, kidney, spleen and brain in the protein-depleted rats than in those given adequate protein. However, the total tissue retention was not significantly different between these groups, so that there was a greater capacity for tissue binding and for body conservation of vitamin B12 in the protein-starved animals.

scholarly journals The effects of dietary histidine, methionine and homocystine on vitamin B12 and folate levels in rat liver

1976 ◽  
Vol 35 (3) ◽  
pp. 299-307 ◽  
Author(s):  
D. L. Williams ◽  
G. H. Spray
Keyword(s):  
Amino Acids ◽  
Body Weight ◽  
Vitamin B12 ◽  
Protein Content ◽  
Rat Liver ◽  
Liver Weight ◽  
Soya Bean ◽  
Vitamin B ◽  
Deficient Diet ◽  
Bean Flour

1. L-histidine (20 g/kg) added to vitamin B12-deficient and cyanocobalamin-supplemented diets based on soya-bean flour reduced the growth of rats given the vitamin B12-deficient diet but stimulated growth of rats given the cyanocobalamin-supplemented diet. Liver weight (g/kg body-weight) increased, but the protein content of the livers decreased, in rats given histidine supplements. The histidine was associated with significantly higher folate concentrations in the livers of cyanocobalamin-supplemented rats.2. Vitamin B12-deficient and cyanocobalamin-supplemented rats were given diets based on a mixture of amino acids that was balanced apart from methionine, which was added in various amounts, and with the addition of homocystine. The only vitamin B12-deficient rats which had reasonable gains in weight were those receiving a diet containing 8 g L-methionine/kg. The remainder, particularly those given diets containing only homocystine, had little or no increase in weight. All the cyanocobalamin-supplemented rats gained weight; those given diets containing 2 and 8 g L-methionine/kg, or 8 g homocystine/kg, had the highest gains.3. There was a tendency for a higher concentration of either methionine or homocystine in the diet to be associated with higher concentrations of both folate and vitamin B12 in the livers.4. In vitamin B12 deficiency methionine appeared to increase the accumulation of folate in the liver, affecting mainly the amounts of polyglutamate derivatives.

scholarly journals Molecularly imprinted membrane for transport of urea, creatinine, and vitamin B12 as a hemodialysis candidate membrane

2021 ◽  
Vol 19 (1) ◽  
pp. 806-817
Author(s):  
Muhammad Cholid Djunaidi ◽  
Nabilah Anindita Febriola ◽  
Abdul Haris
Keyword(s):  
Polyethylene Glycol ◽  
Vitamin B12 ◽  
Kidney Function ◽  
Cross Linking ◽  
Vitamin B ◽  
Molecularly Imprinted ◽  
Selective Transport ◽  
Molecularly Imprinted Membrane ◽  
Better Than ◽  
Imprinted Membrane

Abstract High levels of urea and creatinine in the blood are a sign of decreased kidney function. To remove these substances from the blood, hemodialysis which utilizes membranes could be used. In this study, a molecularly imprinted membrane (MIM) was synthesized for the selective transport of urea. The synthesis is initiated with the polymerization of eugenol into polyeugenol and then into polyeugenoxy acetate (PA). The PA is then contacted with urea and then used as the functional polymer in the synthesis of MIM with polysulfone as the membrane base, and polyethylene glycol as the cross-linking agent. The result was later analyzed with FTIR and SEM-EDX. The membrane is then used in the transport of urea, creatinine, and vitamin B12 and then compared with the non-imprinted membrane (NIM) performance. By using UV-Vis spectrophotometry, the results showed that the membrane with 10 h heating variation is able to transport more urea and is more selective than NIM; this proves that the urea template on the MIM enables it to recognize urea molecules better than creatinine and vitamin B12. The order of transport from the best results is urea > creatinine > vitamin B12.

Röntgenspektroskopische Bestimmung der Wertigkeit des Kobalts im Vitamin B12

1954 ◽  
Vol 9 (8) ◽  
pp. 509-513 ◽  
Author(s):  
G. Boehm ◽  
A. Faessler ◽  
G. Rittmayer
Keyword(s):  
Vitamin B12 ◽  
Vitamin B

Mit einem fokussierenden Spektrographen großer Dispersion wird die Lage der K-Röntgen-absorptionskante des Kobalts in verschiedenen Verbindungen untersucht. Die Ergebnisse zeigen, daß es möglich ist, durch Bestimmung der Kantenlage die Wertigkeit des Kobalts in einer Verbindung zu bestimmen. Die Methode gestattet den eindeutigen Nachweis, daß das Kobalt im Vitamin B12 dreiwertig ist.

scholarly journals Effect of Vitamin-B1 and Vitamin-B12 on the Growth and Carotenoid Content of Haematococcus pluvialis CH-1

2015 ◽  
Vol 7 (9) ◽  
pp. 709-711
Author(s):  
Li-Xin Li ◽  
Zhi-Wei Song ◽  
Shun-Shan Duan ◽  
Ke-Jie Luo ◽  
Ting Li ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Haematococcus Pluvialis ◽  
Carotenoid Content ◽  
Vitamin B

Preparation of Cod Liver Residues and Vitamin B12 Concentrates

1954 ◽  
Vol 11 (4) ◽  
pp. 355-361 ◽  
Author(s):  
Beryl Truscott ◽  
D. G. Gage ◽  
P. L. Hoogland
Keyword(s):  
Vitamin B12 ◽  
Nutritive Value ◽  
Vitamin B ◽  
Sodium Bisulphite ◽  
Drum Drying ◽  
Different Types

As the first part of an investigation of the nutritive value of cod liver, two methods of preparation of cod liver residue were studied, as well as the effect of drum drying the residue, with and without the presence of sodium bisulphite, defatting the dried residue and extracting vitamin B12 from the dried residue.It was found that Vandenheuvel's method of preparation of residue produces very good results. The fresh residue could be dried without appreciable loss of vitamin B12 activity on a double drum dryer, operated with steam at 20 p.s.i.g. Sodium bisulphite afforded some protection during the drying. The most satisfactory results in defatting were obtained by extraction with dichloroethylene. Concentrates with vitamin B12 activity equivalent to 2–4 micrograms per milliliter were produced by extraction of dried, defatted residue with water and evaporation in vacuo.Five different types of residue were prepared for further studies.

scholarly journals The study of clinical profile and vitamin B 12 in dengue fever patients

2021 ◽  
Vol 12 (7) ◽  
pp. 47-51
Author(s):  
Mamatha Tittamegalapalya Ramalingaiah ◽  
Jeetendra Kumar Jogihalli Mood ◽  
Satyanarayana Narayanashetty ◽  
Rashmi Madappa Bhuvaneshappa
Keyword(s):  
Vitamin B12 ◽  
Hospital Stay ◽  
Dengue Fever ◽  
Platelet Transfusion ◽  
Clinical Profile ◽  
Study Patient ◽  
Vitamin B ◽  
Severe Thrombocytopenia ◽  
Duration Of Hospital Stay ◽  
Vitamin B 12

Background: Dengue is an acute infectious febrile illness characterised by thrombocytopenia and platelet dysfunction leading to bleeding manifestations. Vitamin B12 is required for platelet production in the bone marrow. So, deficiency of vitamin B12 in dengue patients can have severe thrombocytopenia. Aims and Objective: Study was aimed to know the clinical profile of dengue fever patients and to correlate serum vitamin B12 level with severity of thrombocytopenia, platelet transfusion and duration of hospital stay. Materials and Methods: This observational study was done on dengue patients for period of 3 months January 2020 to March 2020. Confirmed cases of dengue fever with NS 1 Ag positive & Ig M antibody positive were included in the study. Patient with sepsis, underlying malignancy, autoimmune disorder, hematological disorder, drugs causing thrombocytopenia were excluded from the study. Appropriate statistical methods were applied. Results: Total 50 subjects were included. Majority of subjects were in the age group 31 to 40 years. 50% were males and females respectively. Most common clinical feature was fever and bleeding manifestations. Mean Vitamin B12 was significantly lower among those with severe thrombocytopenia and highest among those with no thrombocytopenia., there was significant difference in mean Platelet transfusion and duration of hospital stay with respect to severity of Platelet count. Conclusion: Dengue fever patients with vitamin B 12 deficiency had moderate to severe thrombocytopenia and more bleeding manifestations. Those patients required more platelet transfusion and increased duration of hospital stay.

Increased intake of vitamin B12, folate, and omega-3 fatty acids to improve cognitive performance in offspring born to rats with induced hypertension during pregnancy

2018 ◽  
Vol 9 (7) ◽  
pp. 3872-3883 ◽  
Author(s):  
Nisha Kemse ◽  
Anvita Kale ◽  
Preeti Chavan-Gautam ◽  
Sadhana Joshi
Keyword(s):  
Fatty Acids ◽  
Folic Acid ◽  
Docosahexaenoic Acid ◽  
Vitamin B12 ◽  
Cognitive Performance ◽  
Vitamin B ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Induced Hypertension

Vitamin B12, folic acid, and docosahexaenoic acid levels are reported to be altered in women with preeclampsia.

Über den Vitamin B12-Gehalt und den Vitamin E-Gehalt der einzelligen Grünalge Scenedesmus obliquus

1958 ◽  
Vol 13 (9) ◽  
pp. 605-610 ◽  
Author(s):  
Hermann Fink ◽  
Elisabeth Herold ◽  
Harry Lundin
Keyword(s):  
Vitamin E ◽  
Vitamin B12 ◽  
Scenedesmus Obliquus ◽  
Vitamin B

In neun Proben der einzelligen Zuchtalge Scenedesmus obliquus, geerntet aus nicht-sterilen Freilandkulturen, wurden Gehalte von Vitamin B12 von 0,02 —1,7 γ/g Trockensubstanz festgestellt. Diese lagen somit wenigstens zwanzig- bis fünfzigmal höher als die von Grünblatt höherer Pflanzen, in denen bisher höchstens Spuren von Vitamin B12 gefunden wurden.Mit den in fünf Chargen gefundenen Werten an Vitamin E von 111—183 γ/g Trockensubstanz entsprach unsere Alge Scenedesmus obliquus etwa Spinat und Weizenkeimlingen, also Pflanzenprodukten mit einem überdurchschnittlichen Gehalt an Vitamin E. Weit überlegen ist sie in dieser Hinsicht tierischen Produkten, z. B. der Milch.Da wir in früheren Studien auch einen sehr hohen biologischen Eiweißwert für das Wachstum der Ratte fanden, muß die Zuchtalge Scenedesmus obliquus, jedenfalls in getrocknetem Zustand, als ein neues interessantes Material von sehr hohem diätetischem Wert angesehen werden, das in seinem ernährungsphysiologischen Verhalten günstige Eigenschaften von tierischen und pflanzlichen Produkten in sich vereinigt.Es ergaben sich keine Anhaltspunkte dafür, den hohen biologischen Wert für das Wachstum nicht in erster Linie dem (verdaulichen) Eiweiß selbst zuzuschreiben und nicht dem Vitamin B12 und Vitamin E der Scenedesmus-Alge.

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