Anti-inflammatory Active Constituents of Aloe arborescens Miller

1991 ◽  
Vol 55 (6) ◽  
pp. 1627-1629 ◽  
Author(s):  
Masatoshi Yamamoto ◽  
Toshio Masui ◽  
Kiyoshi Sugiyama ◽  
Masami Yokota ◽  
Kazuya Nakagomi ◽  
...  
1991 ◽  
Vol 55 (6) ◽  
pp. 1627-1629 ◽  
Author(s):  
Masatoshi YAMAMOTO ◽  
Toshio MASUI ◽  
Kiyoshi SUOIYAMA ◽  
Masami YOKOTA ◽  
Kazuya NAKAGOMI ◽  
...  

Animals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 917 ◽  
Author(s):  
Matteo Mezzetti ◽  
Andrea Minuti ◽  
Massimo Bionaz ◽  
Fiorenzo Piccioli-Cappelli ◽  
Erminio Trevisi

The anti-hyperlipidemic and anti-inflammatory effects exerted by Aloe on monogastric mammals suggest it as a potential strategy to address the tremendous metabolic alterations that affect dairy cows during their transition to calving. A group of 20 multiparous Italian Holstein dairy cows were housed in freestalls and allocated into two homogeneous groups to receive either 200 g/d of water (CTR) or 200 g/day of Aloe arborescens Mill. whole plant homogenate through a rumen tube (AAM) between −14 and 14 days from calving (DFC). From −14 to 35 DFC, the BCS, and milk yield were measured, and blood samples were collected to assess the hematochemical profile. Data underwent ANOVA testing using a mixed model for repeated measurements, including the treatment and time and their interactions as fixed effects. Compared to CTR cows, AAM cows had a less pronounced BCS loss in early lactation (p < 0.01), indicating less mobilization of body reserves. Compared to CTR cows, AAM cows had a lower plasma concentration of nonesterified fatty acids and beta hydroxybutyrate (p < 0.01 and = 0.01 respectively) that, paired with the lower butterfat content and fat/protein ratio in their milk (p = 0.03 and < 0.01 respectively), indicates that Aloe reduced the mobilization of body fats. AAM cows had a reduced concentration of myeloperoxidase in plasma and a lower SCC in milk compared to CTR cows (p = 0.02 for both), indicating an anti-inflammatory effect of Aloe. Furthermore, AAM cows had a lower plasma concentration of ceruloplasmin (p < 0.05) and higher plasma concentration of cholesterol, retinol, and paraoxonase compared to CTR cows (p < 0.01, < 0.01 and < 0.05 respectively), indicating Aloe was effective in mitigating the acute phase response in early lactation. Finally, AAM cows had lower plasma creatinine concentrations around calving (p < 0.05), a lower concentration of plasma bilirubin, and a higher concentration of plasma tocopherol compared to CTR cows (p = 0.01 for both). These data suggest Aloe has anti-hyperlipidemic and anti-inflammatory effects on transition dairy cows that could have ameliorated liver and kidney function disruption and increased the availability of body antioxidants in early lactation.


Author(s):  
Shireen Sabah Kamil ◽  
ImadHadi Hameed ◽  
Lena Fadhil Hamza

Acoruscalamusis a herb used for the appetite and as an aid to the digestion. It is used for fevers, stomach cramps and cholic. Their rhizomes were used for toothache and powdered rhizome for congestion. The rhizome part is also used to treat several diseases like asthma and bronchitis and as sedative. Native tribes treated cough by making a decoction of the plant as a carminative and also for cholic. It is a main medhya drug, which has the property of improving the memory power and intellect. Acoruscalamusis used in the conditions of vata and kapha, stomatopathy, hoarseness, flatulence, dyspepsia, helminthiasis, amenorrhea, dysmenorrheal, nephropathy, calculi, stragury.Acoruscalamusleaves, rhizomes and its essential oil has many biological activities16 like antispasmodic, carminative and also used for treatment of epilepsy, mental ailments, chronic diarrhea, dysentery, bronchial catarrh, intermittent and tumors. It also has the insecticidal, antifungal, antibacterial, tranquilizing, antidiarrhoeal, antidyslipidemic, neuroprotective, antioxidant, anticholinesterase, spasmolytic, vascular modulator activities. The parts used in most of the experimental studies are the leaves, roots and stem of the plant. The dry rhizome contains some of the yellow aromatic oil, calamus oil that are responsible for their medicinal and insecticidal properties. Studies were also done on their rhizome part and in its oils in order to identify the active constituents and its medicinal values.


1977 ◽  
Vol 32 (9-10) ◽  
pp. 731-734 ◽  
Author(s):  
Toshifumi Hirata ◽  
Takayuki Suga

Abstract Several biologically active substances, such as aloenin (1), magnesium lactate, aloe-emodin (4), barbaloin (5), and succinic acid, were found to be contained in the leaf juice of Aloe arborescens Mill. var. natalensis Berger, which has widely been used in domestic medicines. Aloenin (1) and magnesium lactate were elucidated to exhibit an inhibitory action on the gastric juice secretion of rats. Various constituents other than the above bioactive substances were found in the leaves and the roots of the plant.


Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5690
Author(s):  
Hosakatte Niranjana Murthy ◽  
Dayanand Dalawai ◽  
Yaser Hassan Dewir ◽  
Abdullah Ibrahim

Garcinia morella (Gaertn.) Desr. is an evergreen tree that yields edible fruits, oil, and resin. It is a source of “gamboge”, a gum/resin that has a wide range of uses. The fruits, leaves, and seeds of this tree are rich in bioactive compounds, including xanthones, flavonoids, phenolic acids, organic acids, and terpenoids. Evidence from different studies has demonstrated the antioxidant, antifungal, antiviral, hepatoprotective, anticancer, anti-inflammatory, antibacterial, and larvicidal activities of the fruit, leaf, and seed extracts of G. morella. This review summarizes the information on the phytochemicals of G. morella and the biological activities of its active constituents.


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