Immune responses and behavior alterations of Persian sturgeon fingerlingsAcipenser persicusexposed to sublethal concentrations of diazinon

2010 ◽  
Vol 92 (1) ◽  
pp. 159-167 ◽  
Author(s):  
Z. Padash-Barmchi ◽  
A. Safahieh ◽  
M. Bahmani ◽  
A. Savari ◽  
R. Kazemi
Keyword(s):  
Immune Responses ◽  
Persian Sturgeon ◽  
And Behavior ◽  
Sublethal Concentrations

scholarly journals Immune responses during the larval stages of Mytilus galloprovincialis: Metamorphosis alters immunocompetence, body shape and behavior

2013 ◽  
Vol 35 (2) ◽  
pp. 438-447 ◽  
Author(s):  
Pablo Balseiro ◽  
Rebeca Moreira ◽  
Rubén Chamorro ◽  
Antonio Figueras ◽  
Beatriz Novoa
Keyword(s):  
Immune Responses ◽  
Body Shape ◽  
Mytilus Galloprovincialis ◽  
Larval Stages ◽  
And Behavior

scholarly journals Hippocampal astroglial hypertrophy in mice subjected to early life maternal deprivation

2021 ◽  
Author(s):  
Arnab Nandi ◽  
Garima Virmani ◽  
Swananda Marathe
Keyword(s):  
Immune Responses ◽  
Life Stress ◽  
Early Life ◽  
Maternal Separation ◽  
Early Life Stress ◽  
Stratum Radiatum ◽  
Late Adulthood ◽  
Synaptic Physiology ◽  
And Behavior

Early-life stress (ELS), including chronic deprivation of maternal care, exerts persistent life-long effects on animal physiology and behavior, and is associated with several neurodevelopmental disorders. Long-lasting changes in neuronal plasticity and electrophysiology are documented extensively in the animal models of ELS. However, the role of astroglia in the lasting effects of ELS remains elusive. Astrocytes are intricately involved in the regulation of synaptic physiology and behavior. Moreover, astrocytes play a major role in the innate and adaptive immune responses in the central nervous system (CNS). The role of immune responses and neuroinflammation in the altered brain development and persistent adverse effects of ELS are beginning to be explored. Innate immune response in the CNS is characterized by a phenomenon called astrogliosis, a process in which astrocytes undergo hypertrophy, along with changes in gene expression and function. While the immune activation and neuroinflammatory changes concomitant with ELS, or in juveniles and young adults have been reported, it is unclear whether mice subjected to ELS exhibit astrogliosis-like alterations well into late-adulthood. Here, we subjected mice to maternal separation from postnatal day 2 to day 22 and performed comprehensive morphometric analysis of hippocampal astrocytes during late-adulthood. We found that the astrocytes in the stratum radiatum region of the CA1 hippocampal subfield from maternally separated mice exhibit significant hypertrophy as late as 8 months of age, revealing the crucial changes in astrocytes that manifest long after the cessation of ELS. This study highlights the persistence of neuroinflammatory changes in mice exposed to ELS.

Interruption of immune responses in primary macrophages exposed to nonylphenol provides insights into the role of ER and NF-KB in immunotoxicity of Persian sturgeon

2019 ◽  
Vol 86 ◽  
pp. 125-134 ◽  
Author(s):  
Sara Rastgar ◽  
Abdolali Movahedinia ◽  
Negin Salamat ◽  
Amir Parviz Salati ◽  
Ebrahim Zabihi
Keyword(s):  
Immune Responses ◽  
Persian Sturgeon

scholarly journals CD3 and Immunoglobulin G Fc Receptor Regulate Cerebellar Functions

2007 ◽  
Vol 27 (14) ◽  
pp. 5128-5134 ◽  
Author(s):  
Kazuhiro Nakamura ◽  
Hirokazu Hirai ◽  
Takashi Torashima ◽  
Taisuke Miyazaki ◽  
Hiromichi Tsurui ◽  
...  
Keyword(s):  
Immune Responses ◽  
Immunoglobulin G ◽  
High Speed ◽  
Fc Receptor ◽  
Purkinje Neurons ◽  
Normal Brain ◽  
Neuronal Functions ◽  
And Behavior ◽  
Normal Brain Development ◽  
Deficient Mice

ABSTRACT The immune and nervous systems display considerable overlap in their molecular repertoire. Molecules originally shown to be critical for immune responses also serve neuronal functions that include normal brain development, neuronal differentiation, synaptic plasticity, and behavior. We show here that FcγRIIB, a low-affinity immunoglobulin G Fc receptor, and CD3 are involved in cerebellar functions. Although membranous CD3 and FcγRIIB are crucial regulators on different cells in the immune system, both CD3ε and FcγRIIB are expressed on Purkinje cells in the cerebellum. Both CD3ε-deficient mice and FcγRIIB-deficient mice showed an impaired development of Purkinje neurons. In the adult, rotarod performance of these mutant mice was impaired at high speed. In the two knockout mice, enhanced paired-pulse facilitation of parallel fiber-Purkinje cell synapses was shared. These results indicate that diverse immune molecules play critical roles in the functional establishment in the cerebellum.

scholarly journals The Effects of Natural Biopesticide from Mirabilis jalapa toward the Immune System of Spodoptera litura

2018 ◽  
Author(s):  
Dina Maulina ◽  
Sutiman Bambang Sumitro ◽  
Mohamad Amin ◽  
Sri Rahayu Lestari ◽  
Muhammad Aziz ◽  
...  
Keyword(s):  
Immune Responses ◽  
Phagocytic Activity ◽  
Spodoptera Litura ◽  
Insect Pest ◽  
Control Group ◽  
Agricultural Pest ◽  
Chemical Substances ◽  
Mirabilis Jalapa ◽  
Sublethal Concentrations ◽  
Control Samples

Biological control provides a safer alternative to reduce the population of agricultural pest. Mirabilis jalapa is one of biopesticides containing chemical substances that have a feeding deterrent property against Spodoptera litura as folifagus insect pest. This study aimed to analyze the humoral and cellular immunes responses of S. litura after exposure to biopesticide extracted from M. jalapa. The measured indicator immune responses were activity of hemocyte, lectin, phenoloxidase (PO), and phagocytic activity. The results showed that the average total hemocyte was different significantly depending on the treatment. Exposure to 0.1% and 0.2% (w/v) of M. jalapa extract increased the total number of hemocytes as much as 38.08% and 64.15%, respectively. Lectin was quickly formed at 0.1% and 0.2% (w/v) concentrations. The amount of PO enzymes was significantly different at sublethal concentrations compared with control samples (P < 0.05). The highest increase in PO activity occurred at 2 h post-treatment and at M. jalapa extract concentrations of 0.2% (592.33 IU/mg) and 0.1% (521.33 IU/mg), whereas the highest concentration of the extract (0.8% w/v) caused a decrease in lectin and PO activities. In terms of phagocytic activity, the proportion of phagocytosis cells were 47.62% in control group, and decreased significanlty in both concentrations exposure.

Physiological, ionoregulatory, metabolic and immune responses of Persian sturgeon,Acipenser persicus(Borodin, 1897) to stress

2015 ◽  
Vol 47 (12) ◽  
pp. 3729-3739 ◽  
Author(s):  
Seyyed Morteza Hoseini ◽  
Lluis Tort ◽  
Mohammad Hadi Abolhasani ◽  
Hamid Rajabiesterabadi
Keyword(s):  
Immune Responses ◽  
Persian Sturgeon ◽  
Acipenser Persicus ◽  
Persian Sturgeon Acipenser Persicus

scholarly journals Dendritic Cells: Neglected Modulators of Peripheral Immune Responses and Neuroinflammation in Mood Disorders?

Cells ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 941
Author(s):  
Rafael Leite Dantas ◽  
Jana Freff ◽  
Oliver Ambrée ◽  
Eva C. Beins ◽  
Andreas J. Forstner ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Animal Models ◽  
Immune Responses ◽  
Mood Disorders ◽  
Current Knowledge ◽  
Serum Levels ◽  
Self Tolerance ◽  
Antigen Presenting ◽  
And Behavior ◽  
The Impact

Affective disorders (AD) including major depressive disorder (MDD) and bipolar disorder (BD) are common mood disorders associated with increased disability and poor health outcomes. Altered immune responses characterized by increased serum levels of pro-inflammatory cytokines and neuroinflammation are common findings in patients with AD and in corresponding animal models. Dendritic cells (DCs) represent a heterogeneous population of myeloid cells that orchestrate innate and adaptive immune responses and self-tolerance. Upon sensing exogenous and endogenous danger signals, mature DCs secrete proinflammatory factors, acquire migratory and antigen presenting capacities and thus contribute to neuroinflammation in trauma, autoimmunity, and neurodegenerative diseases. However, little is known about the involvement of DCs in the pathogenesis of AD. In this review, we summarize the current knowledge on DCs in peripheral immune responses and neuroinflammation in MDD and BD. In addition, we consider the impact of DCs on neuroinflammation and behavior in animal models of AD. Finally, we will discuss therapeutic perspectives targeting DCs and their effector molecules in mood disorders.

How Homo economicus lost her mind and how we can revive her

2018 ◽  
Vol 41 ◽  
Author(s):  
Peter DeScioli
Keyword(s):  
Economic Thought ◽  
History Of Economic Thought ◽  
Homo Economicus ◽  
Economic Theories ◽  
Target Article ◽  
History Of ◽  
The Mind ◽  
And Behavior

AbstractThe target article by Boyer & Petersen (B&P) contributes a vital message: that people have folk economic theories that shape their thoughts and behavior in the marketplace. This message is all the more important because, in the history of economic thought, Homo economicus was increasingly stripped of mental capacities. Intuitive theories can help restore the mind of Homo economicus.

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