Testicular microlithiasis — a possibly premalignant condition

1998 ◽  
Vol 39 (5) ◽  
pp. 583-586 ◽  
Author(s):  
A. Berger ◽  
K. Brabrand
Keyword(s):  
Rare Condition ◽  
Review Of The Literature ◽  
Testicular Microlithiasis ◽  
Premalignant Condition ◽  
Testicular Malignancy

Testicular microlithiasis (TM) is a rare condition characterized by the presence of multiple small intratesticular calcifications. the etiology is unknown but the condition has been observed in a variety of different urological conditions. We report on 5 cases diagnosed by ultrasonography at our departments from 1992 to 1994 A review of the literature plus our present 5 cases gives a total of 124 reported cases of TM. TM was associated with testicular malignancy in 44 patients (35%) of whom 24 (19%) had a seminoma and 20 (16%) a non-seminoma. There were 4 reports of testicular malignancy developing in patients with a prior diagnosis of TM. the condition should be considered premalignant and a careful follow-up of TM patients is advocated

scholarly journals Tropheryma whipplei Endocarditis: Case Presentation and Review of the Literature

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Michael McGee ◽  
Stephen Brienesse ◽  
Brian Chong ◽  
Alexander Levendel ◽  
Katy Lai
Keyword(s):  
Heart Failure ◽  
Rare Condition ◽  
Tropheryma Whipplei ◽  
Review Of The Literature ◽  
Case Presentation ◽  
Gastrointestinal Manifestations ◽  
Presenting Symptoms ◽  
Physician Awareness ◽  
Culture Negative

Abstract Whipple’s disease is a rare infective condition, classically presenting with gastrointestinal manifestations. It is increasingly recognized as an important cause of culture-negative endocarditis. We present a case of Whipple’s endocarditis presenting with heart failure. A literature review identified 44 publications documenting 169 patients with Whipple’s endocarditis. The average age was 57.1 years. There is a clear sex predominance, with 85% of cases being male. Presenting symptoms were primarily articular involvement (52%) and heart failure (41%). In the majority of cases, the diagnosis was made on examination of valvular tissue. Preexisting valvular abnormalities were reported in 21%. The aortic valve was most commonly involved, and multiple valves were involved in 64% and 23% of cases, respectively. Antibiotic therapy was widely varied and included a ceftriaxone, trimethoprim, and sulfamethoxazole combination. The average follow-up was 20 months, and mortality was approximately 24%. Physician awareness is paramount in the diagnosis and management of this rare condition.

scholarly journals Pediatric testicular microlithiasis through four clinical case studies: review of the literature and proposal of clinical guidelines

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Amina Chaka ◽  
Amine Fredj Daassa ◽  
Wadye Hamdouni ◽  
Kamel Ktari ◽  
Rachida Laamiri ◽  
...  
Keyword(s):  
Clinical Case ◽  
Main Body ◽  
Review Of The Literature ◽  
Testicular Microlithiasis ◽  
Clinical Observations ◽  
Histological Criteria ◽  
Monitoring Framework ◽  
Clinical Case Studies ◽  
First Time

Abstract Background Testicular microlithiasis in children was defined for the first time in 1961 based on histological criteria. There should be more than 5 calcifications per testicle in order to say that the patient has testicular microlithiasis. It has three different echographic grades depending on the number of calcifications. However, this disease is uncommon, with inaccurate prevalence and no certain information about its evolution or etiology. Main body We studied 4 clinical cases of children diagnosed with testicular microlithiasis, in light of the conducted review of the literature, and we defined the characteristics of this disease and proposed a management and monitoring framework based on the clinical observations. Conclusion There is a link between testicular microlithiasis and testicular cancer. Therefore, it is recommended to make a regular follow-up of children who present testicular microlithiasis with the presence of risk factors.

scholarly journals Superior Dislocation of the Patella Treated by Closed Reduction: A Rare Case Report and Review of the Literature

2007 ◽  
Vol 14 (4) ◽  
pp. 225-227 ◽  
Author(s):  
R Lai ◽  
YK Lau
Keyword(s):  
Closed Reduction ◽  
Rare Condition ◽  
Review Of The Literature ◽  
Range Of Movement ◽  
Full Extension ◽  
Rare Case Report ◽  
Superior Dislocation ◽  
Knee Problem ◽  
Dislocation Of The Patella

Superior dislocation of the patella is a rare condition. We report a 70-year-old gentleman with his patella lower pole osteophyte interlocked with the anterior femoral condyles after hyperextension. The patella was reduced successfully with proper reduction technique under sedation. The active range of movement ranged from full extension to 120-degree flexion a few minutes after reduction. He walked unaided afterwards. There was no knee problem in two years of follow-up. On reviewing the literature, only 20 cases were reported till year 2007 worldwide and 19 cases could be treated by closed reduction with or without sedation.

scholarly journals Melkersson–Rosenthal Syndrome in Childhood: Report of Three Paediatric Cases and a Review of the Literature

2019 ◽  
Vol 16 (7) ◽  
pp. 1289 ◽  
Author(s):  
Savasta ◽  
Rossi ◽  
Foiadelli ◽  
Licari ◽  
Elena Perini ◽  
...  
Keyword(s):  
Literature Review ◽  
Genetic Factors ◽  
Treatment Success ◽  
Rare Condition ◽  
Allergic Reactions ◽  
Immune Functions ◽  
Review Of The Literature ◽  
Peripheral Facial Palsy ◽  
Fissured Tongue

Melkersson–Rosenthal syndrome (MRS) in children is a rare condition, clinically characterised by a triad of synchronous or metachronous symptoms: recurrent peripheral facial palsy, relapsing orofacial oedema, and a fissured tongue; the most recent review published on the topic has reported 30 published patients. The aetiology of this disease is still unclear. However, genetic factors, as well as alterations in immune functions, infections, and allergic reactions have been postulated. We report three children suffering from MRS and perform a literature review of paediatric cases. Taking into account that clinical and laboratoristical criteria for the diagnosis of MRS are lacking, this syndrome is probably underestimated, and we suggest increasing awareness of such a rare syndrome. Close multidisciplinary follow-up of these children with a team composed by paediatricians, neurologists, neuro-ophthalmologists, dermatologists, and otolaryngologists is crucial to guarantee exhaustive management and treatment success, while minimising relapses.

Nonunion of a Fracture of the Lateral Malleolus: A Case Report and Review of the Literature

1997 ◽  
Vol 18 (1) ◽  
pp. 50-52 ◽  
Author(s):  
Nahshon Rand ◽  
Ram Mosheiff ◽  
Meir Liebergall
Keyword(s):  
Internal Fixation ◽  
Clinical Signs ◽  
Rare Condition ◽  
Autologous Bone Graft ◽  
Male Gender ◽  
Lateral Malleolus ◽  
Review Of The Literature ◽  
Weber Type ◽  
Type C

Nonunion of a fracture of the lateral malleolus is a rare condition. We present a case of established nonunion of a fracture of the lateral malleolus confirmed and treated surgically, using debridement and internal fixation with autologous bone graft. At 5-year follow-up, the fracture was united but the patient still showed clinical signs of reflex sympathetic dystrophy. Male gender, supination fractures, Weber type C fractures, and primary internal fixation are cited as possible risk factors. Prognosis is variable.

Langerhans Cell Histiocytosis of the Adult Cervical Spine: A Case Report and Literature Review

2018 ◽  
Vol 80 (01) ◽  
pp. 049-052 ◽  
Author(s):  
Ekkehard Hewer ◽  
Christian Ulrich ◽  
Ralph Schär
Keyword(s):  
Differential Diagnosis ◽  
Cervical Spine ◽  
Langerhans Cell Histiocytosis ◽  
Osteolytic Lesion ◽  
Rare Condition ◽  
Langerhans Cell ◽  
Review Of The Literature ◽  
Young Adult Patient ◽  
Important Differential Diagnosis

AbstractA 36-year-old man was diagnosed with Langerhans cell histiocytosis (LCH) of the cervical spine with a unifocal expansive osteolytic lesion of C4. The surgical management with a 2-year follow-up and a review of the literature on LCH of the cervical spine are presented. Although a rare condition, LCH is an important differential diagnosis of any osteolytic lesion in the cervical spine with localized pain in a young adult patient. Review of the literature suggests a higher prevalence of LCH lesions affecting the cervical spine as compared with the thoracic or lumbar spine than historically reported.

Testicular Microlithiasis, Long Term Experience of a Single Institution

2011 ◽  
Vol 4 (6) ◽  
pp. 248-252
Author(s):  
Michael Kimuli ◽  
Ian Beckley ◽  
James Cast ◽  
Graeme Cooksey
Keyword(s):  
Surveillance Program ◽  
Testicular Microlithiasis ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Scrotal Ultrasound ◽  
Testicular Malignancy ◽  
Associated Risk Factors ◽  
Self Examination

Introduction: Several studies have reported an association between testicular microlithiasis (TML) and testicular malignancy with some suggesting the concordance to be as high as 40%. In 2000, we published a large study of 4819 patients referred for scrotal ultrasound (USS) at four referral centers. Based on our findings we recommended ultrasound surveillance of patients with TML. The aim of this study was to determine the long-term outcome of our surveillance regimen. Methods: We reviewed the prospective database of all men diagnosed with TML at USS between 1996 and 2006 at our institution. All patients diagnosed with TML were scheduled for six-monthly USS and in addition they were given instructions to perform regular self-examination. Fifteen years after the surveillance program was commenced, all patients were contacted and asked to complete a short questionnaire. Results: 57 men were diagnosed with TML with no concurrent or previous testicular tumour. The mean period of follow up was 28.4 months (3–102). Only one man developed testicular cancer during the follow up period. Conclusions: We currently recommend regular testicular self-examination of all men with TML and reserve USS surveillance for selected patients with associated risk factors for testicular malignancy.

scholarly journals Pre-eruptive Intra-Coronal Resorption: A report of two cases and review of the literature

2021 ◽  
Author(s):  
Michelle Briner Garrido ◽  
Joanne Briner Prenafeta ◽  
Rohan Jagtap ◽  
Christopher D. Matesi ◽  
Andres Briner
Keyword(s):  
Pediatric Patients ◽  
Radiographic Finding ◽  
Rare Condition ◽  
Review Of The Literature ◽  
Variable Depth ◽  
Radiographic Findings ◽  
Second Molar ◽  
Unerupted Tooth ◽  
Mandibular Second Molar

Pre-eruptive intracoronary resorption is a rare condition mainly affecting pediatric patients. It is a radiographic finding in the dentin of the crown of an unerupted tooth just below the enamel-dentin junction. It is visualized in radiographs as a radiolucent coronal lesion of variable depth; it is well-defined and located in the dentin adjacent to the amelodentinal limit of an unerupted tooth. Historically, this lesion was misdiagnosed as caries and was misnamed pre-eruptive caries, when in reality they were pre-eruptive intracoronal resorptions. We present two rare cases of pre-eruptive intracoronary resorption in patients that needed radiographs for orthodontic purposes. The Oral & Maxillofacial Radiologist detected the existence of pre-eruptive intracoronary resorption in mandibular second premolars and mandibular second molar. These radiographic findings provided the clinician with the advantage of knowing this condition before teeth eruption, allowing for conservative treatment and periodic radiographic follow-up.

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