Formulation, development and in vitro characterization of modified release tablets of capecitabine

2019 ◽  
Vol 46 (1) ◽  
pp. 20-30
Author(s):  
Sachin S. Gaikwad ◽  
Rohini D. Avhad ◽  
Ramesh S. Kalkotwar
Author(s):  
Ishwari Choudhary ◽  
Preeti K. Suresh

This study was aimed at the development of natamycin loaded nano-structured lipid carriers (NLCs) and their characterization for physicochemical properties i.e., Fourier Transform Infrared (FTIR), UV-Visible spectroscopy, meting point, solubility profile and partition coefficient. FTIR and Differential Scanning Calorimetry (DSC) permit the characterization of the drug, excipients and binary mixture and thus assisted in predicting the compatibility of natamycin with other excipients. Lipid screening for formulation of NLCs were performed by their solubility and drug affinity studies. High homogenization and sonication method was employed for the development of natamycin loaded NLCs and it was characterized for vesicle size, zeta potential, % entrapment efficiency, viscosity, pH and percentage drug release up to 12 h.


2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Amjad Hussain ◽  
Maham Misbah ◽  
Nasir Abbas ◽  
Muhammad Irfan ◽  
Muhammad Sohail Arshad ◽  
...  

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