Concentrations of lead, cadmium, and zinc in human heart muscle and aorta after acute myocardial infarction.

1982 ◽  
Vol 1 (3) ◽  
pp. 255-262 ◽  
Author(s):  
M Speich
1991 ◽  
Vol 24 (2) ◽  
pp. 195-201 ◽  
Author(s):  
Takao Tanaka ◽  
Yuzo Hirota ◽  
Koh-Ichi Sohmiya ◽  
Sinzo Nishimura ◽  
Keishiro Kawamura

1997 ◽  
Vol 43 (8) ◽  
pp. 1372-1378 ◽  
Author(s):  
Junnichi Ishii ◽  
Jian-hua Wang ◽  
Hiroyuki Naruse ◽  
Shinn Taga ◽  
Masatomo Kinoshita ◽  
...  

Abstract We compared the diagnostic utility of serum concentrations of human heart-type cytoplasmic fatty acid-binding protein (H-FABPc), myoglobin, and their ratio for the early diagnosis of acute myocardial infarction (AMI) in 104 healthy volunteers and 165 patients at admission within 6 h of the onset of chest pain. The ROC curves of the H-FABPc [0.946, 95% confidence interval (CI) = 0.913–0.979] and myoglobin (0.895, 95% CI = 0.846–0.944) between patients with AMI and healthy volunteers were significantly greater than the area under the ratio of myoglobin to H-FABPc (0.823, 95% CI = 0.765–0.881). In 165 patients, the sensitivity (81.8%, 95% CI = 74.2–89.4%), specificity (86.4%, 95% CI = 78.1–94.6%), and predictive accuracy (83.6%, 95% CI = 78.0–89.3%) of H-FABPc >12 μg/L in diagnosing AMI were significantly higher than those of myoglobin, and were similar to those of the combination of H-FABPc >12 μg/L and the ratio ≤14. We conclude that H-FABPc is a more sensitive and specific marker than myoglobin for the early diagnosis of AMI, and that their ratio cannot give a clear advantage over the measurement of H-FABPc alone.


1980 ◽  
Vol 26 (12) ◽  
pp. 1662-1665 ◽  
Author(s):  
M Speich ◽  
B Bousquet ◽  
G Nicolas

Abstract Atomic absorption spectrometry was used to measure magnesium, calcium, and sodium, and emission spectrometry to measure potassium, in myocardium (left and right ventricles) of 26 control subjects who died of acute trauma. Results were expressed in mumol/g of proteins. Mg/Ca and K/Na ratios were also determined. The same measurements were made in 24 patients who died from acute myocardial infarction. Samples were also taken from the necrotic area. Mg/Ca and K/Na ratios were significantly higher in the left ventricle of both populations, thus providing evidence of anatomical and physiological differences between the two ventricles. As a result of cytolysis and anoxia, the Mg/Ca ratio was very significantly inverted, and the K/Na ratio very significantly smaller, for samples from the necrotic area. In these clinical conditions arrhythmias could certainly be considered likely, and there is reason to believe that magnesium depletion may be a cause of arrhythmias.


1981 ◽  
Vol 102 (3) ◽  
pp. 324-329 ◽  
Author(s):  
Tsutomu Iwasaki ◽  
Lair G.T. Ribeiro ◽  
Duarte B. Faria ◽  
Wai-Man Cheung ◽  
Peter R. Maroko

2013 ◽  
Vol 35 (6) ◽  
pp. 376-385 ◽  
Author(s):  
A. M. van der Laan ◽  
E. N. ter Horst ◽  
R. Delewi ◽  
M. P. V. Begieneman ◽  
P. A. J. Krijnen ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document