Biological rhythms, chronodisruption and chrono-enhancement: The role of physical activity as synchronizer in correcting steroids circadian rhythm in metabolic dysfunctions and cancer

2018 ◽  
Vol 35 (9) ◽  
pp. 1185-1197 ◽  
Author(s):  
Jacopo Antonino Vitale ◽  
Giovanni Lombardi ◽  
Andi Weydahl ◽  
Giuseppe Banfi
Keyword(s):  
Physical Activity ◽  
Circadian Rhythm ◽  
Biological Rhythms ◽  
Metabolic Dysfunctions

scholarly journals Role of biological rhythms in the performance of physical activity

2017 ◽  
Vol 6 (3) ◽  
pp. 125-134 ◽  
Author(s):  
Takahiro Sato ◽  
Takanori Ida ◽  
Masayasu Kojima
Keyword(s):  
Physical Activity ◽  
Biological Rhythms

scholarly journals The role of depressive symptoms and symptom dimensions in actigraphy-assessed sleep, circadian rhythm, and physical activity

2021 ◽  
pp. 1-7
Author(s):  
Sonia Difrancesco ◽  
Brenda W. J.H. Penninx ◽  
Harriëtte Riese ◽  
Erik J. Giltay ◽  
Femke Lamers
Keyword(s):  
Physical Activity ◽  
Circadian Rhythm ◽  
Depressive Symptoms ◽  
Sleep Disturbances ◽  
Depressive Symptomatology ◽  
Night Time ◽  
Time Activity ◽  
Symptom Dimensions ◽  
Monitor Treatment Response

Abstract Background Considering the heterogeneity of depression, distinct depressive symptom dimensions may be differentially associated with more objective actigraphy-based estimates of physical activity (PA), sleep and circadian rhythm (CR). We examined the association between PA, sleep, and CR assessed with actigraphy and symptom dimensions (i.e. mood/cognition, somatic/vegetative, sleep). Methods Fourteen-day actigraphy data of 359 participants were obtained from the Netherlands Study of Depression and Anxiety. PA, sleep, and CR estimates included gross motor activity (GMA), sleep duration (SD), sleep efficiency (SE), relative amplitude between daytime and night-time activity (RA) and sleep midpoint. The 30-item Inventory of Depressive Symptomatology was used to assess depressive symptoms, which were categorised in three depression dimensions: mood/cognition, somatic/vegetative, and sleep. Results GMA and RA were negatively associated with higher score on all three symptom dimensions: mood/cognition (GMA: β = −0.155, p < 0.001; RA: β = −0.116, p = 0.002), somatic/vegetative (GMA: β = −0.165, p < 0.001; RA: β = −0.133, p < 0.001), sleep (GMA: β = −0.169, p < 0.001; RA: β = −0.190, p < 0.001). The association with sleep was more pronounced for two depression dimensions: longer SD was linked to somatic/vegetative (β = 0.115, p = 0.015) dimension and lower SE was linked to sleep (β = −0.101, p = 0.011) dimension. Conclusion As three symptom dimensions were associated with actigraphy-based low PA and dampened CR, these seem to be general indicators of depression. Sleep disturbances appeared more linked to the somatic/vegetative and sleep dimensions; the effectiveness of sleep interventions in patients reporting somatic/vegetative symptoms may be explored, as well as the potential of actigraphy to monitor treatment response to such interventions.

Major Depressive Disorder and Bipolar Disorder Subtypes Differ in their Genetic Correlations with Physical Activity, Circadian Rhythm, and Sleep

2021 ◽  
Author(s):  
Lea Sirignano ◽  
Fabian Streit ◽  
Josef Frank ◽  
Lea Zillich ◽  
Stephanie Witt ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bipolar Disorder ◽  
Major Depressive Disorder ◽  
Circadian Rhythm ◽  
Mood Disorders ◽  
Genetic Correlations ◽  
Biological Rhythms ◽  
Moderate Activity ◽  
Healthy Controls ◽  
Major Depressive

Abstract Alterations in biological rhythms are features of mood disorders. Patients suffering from major depressive disorder (MDD) show decreased physical activity compared to healthy controls. Bipolar disorder (BIP) patients differ in their activity patterns during different mood phases, and in comparison to their non-affected relatives and healthy controls. In both MDD and BIP, circadian rhythms can be disrupted, accompanied by sleep problems and changes in sleep duration. It is unclear whether the observed associations are due to common etiology or if they are influenced by the current mood state in which they are observed. Here, we used summary statistics from large-scale genome-wide association analysis (GWAS) to test the genetic correlations of MDD, BIP-I, and BIP-II with physical activity (overall physical activity, moderate activity, sedentary behavior), circadian rhythm (relative amplitude) and sleep features (sleep duration, daytime sleepiness). MDD showed positive genetic correlations with sedentary behavior, and negative correlations with overall physical activity and moderate activity, while BIP-I showed associations in the opposite direction. MDD and BIP-II had negative genetic correlations with relative amplitude. All mood disorders were positively genetically correlated with daytime sleepiness. The correlational patterns show that MDD and BIP-I differ the most in their correlations with biological rhythms with BIP-II seemingly occupying a intermediate position. Furthermore, our results suggest that the clinically observed associations between mood disorders and biological rhythms have shared genetic underpinnings. Future research considering possible joint mechanisms may offer potential avenues for improving disease detection and treatment.

scholarly journals Chronobiological features of primary headaches and the role of melatonin in the regulation of biological rhythms

2019 ◽  
pp. 33-38
Author(s):  
E. M. Evdokimova ◽  
M. G. Poluektov ◽  
G. R. Tabeyeva
Keyword(s):  
Circadian Rhythm ◽  
Cluster Headache ◽  
Suprachiasmatic Nucleus ◽  
Seasonal Pattern ◽  
Biological Rhythms ◽  
Primary Headaches ◽  
Melatonin Secretion ◽  
Clinical Observations

Frequency is considered as a key sign of the course of some forms of primary headaches (PH). One of the most prominent representatives is the hypnical and cluster headache, which predetermined their name. Clinical observations demonstrate a clear circadian rhythm and seasonal pattern of cluster headache (CH) and migraine (M) attacks. In accordance with modern concepts, the phenomenon of the periodicity of painful episodes of a number of forms of primary headaches is associated with dysfunction of the suprachiasmatic nucleus of the hypothalamus, the main pacemaker of biological rhythms. The connection of PH with chronopathology is confirmed by revealing the disturbances of melatonin secretion in CH and M. Melatonin has proven to be effective in treatment of these PH.

ROLE OF THE CENTERS OF THE CENTRAL AND INDEPENDENT CONTOURS IN REGULATION OF THE INTIMATE RHYTHM AT PERFORMANCE OF STANDARD PHYSICAL ACTIVITY

ASJ. ◽  
2020 ◽  
Vol 2 (40) ◽  
pp. 22-31
Author(s):  
A.B. Shutov ◽  
A.A. Matskanjuk ◽  
C. V. Korney
Keyword(s):  
Physical Activity ◽  
Nervous System ◽  
Analysis Time ◽  
Vegetative Nervous System ◽  
Distinctive Features

Use of a method of share tendencies in the analysis time of some R-R intervals of the electrocardiogram after performance of 20 knee-bends and after 1 minute of restoration has allowed to establish a role of the centers of vegetative nervous system in restoration of a rhythm of heart at 4-th level of dynamic hierarchy. After 20-ти knee-bends and through 1 minutes of restoration the maximum vegetative centers of the central contour dominate. In interaction of the central and independent contours each center entering into them is characterized with distinctive features of dynamics which are shown in an increasing role of the centers of an independent contour after 1 minute of restoration.

Physical activity promotion in primary health care in Slovenia

2014 ◽  
Vol 62 (2) ◽  
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Health Promotion ◽  
Health Professionals ◽  
Healthy Lifestyle ◽  
Graduate Nurses ◽  
Primary Health ◽  
The Family ◽  
Prevention Of Cardiovascular Disease

In Slovenia, the role of general practitioners in counselling physical activity for prevention of cardiovascular disease (CVD) is well recognized. The role of general practitioners in advising healthy lifestyle for individuals who are at risk of developing CVD is formally defined in the National Program for Primary Prevention of Cardiovascular Disease, which has been running since 2001. Part of the program is counselling on healthy lifestyle including physical activity, performed in all health centres across the country. First a screening and medical examination is performed. In case of higher risk for CVD (>20%) the physician should give advice on the particular risk factor and direct patients to health-education centres, where they can participate in healthy lifestyle workshops lead by health professionals. Physicians and other health professionals who are involved in the implementation of prevention activities within the program need knowledge and skills that are crucial for successful counselling on healthy lifestyle. The educational program “basic education in health promotion and prevention of chronic non-communicable diseases in primary health care/family medicine” consists of two parts. The first part of the training is open to all health professionals working within the program. The second part is intended for health professionals working in health-education workshops. In the last few years a new family practice model has been introduced and disseminated. Some duties of the family physician, including health promotion and counselling, are being transferred to graduate nurses who become part of the family practice team. This new division of work undoubtedly brings many advantages, both in terms of the work organization, and of high-quality patient care. Nevertheless preventive action cannot be fully passed on to graduate nurses. Careful planning and education are needed to ensure a comprehensive approach in healthy life style counselling.

Sign in / Sign up

Export Citation Format

Share Document