Comparing self-affirmation manipulations to reduce alcohol consumption in university students

Author(s):  
Katharina Sophie Vogt, ◽  
John Stephenson, ◽  
Paul Norman,
1998 ◽  
Vol 33 (11) ◽  
pp. 2303-2321 ◽  
Author(s):  
Chudley E. Werch ◽  
Deborah M. Pappas ◽  
Joan M. Carlson ◽  
Carlo C. Diclemente

2021 ◽  
Author(s):  
Gaurav Bedse ◽  
Nathan D. Winters ◽  
Anastasia Astafyev ◽  
Toni A. Patrick ◽  
Vikrant R. Mahajan ◽  
...  

ABSTRACTAlcohol use disorder (AUD) is associated with substantial morbidity, mortality, and societal cost, and pharmacological treatment options for AUD are limited. The endogenous cannabinoid (eCB) signaling system is critically involved in reward processing and alcohol intake is positively correlated with release of the eCB ligand 2-Arachidonoylglycerol (2-AG) within reward neurocircuitry. Here we show that genetic and pharmacological inhibition of diacylglycerol lipase (DAGL), the rate limiting enzyme in the synthesis of 2-AG, reduces alcohol consumption in a variety of preclinical models ranging from a voluntary free-access model to aversion resistant-drinking, and dependence-like drinking induced via chronic intermittent ethanol vapor exposure in mice. DAGL inhibition also prevented ethanol-induced suppression of GABAergic transmission onto midbrain dopamine neurons, providing mechanistic insight into how DAGL inhibition could affect alcohol reward. Lastly, DAGL inhibition during either chronic alcohol consumption or protracted withdrawal was devoid of anxiogenic and depressive-like behavioral effects. These data suggest reducing 2-AG signaling via inhibition of DAGL could represent a novel approach to reduce alcohol consumption across the spectrum of AUD severity.


2012 ◽  
Vol 15 (11) ◽  
pp. 2131-2139 ◽  
Author(s):  
Carlos Moreno-Gómez ◽  
Dora Romaguera-Bosch ◽  
Pedro Tauler-Riera ◽  
Miquel Bennasar-Veny ◽  
Jordi Pericas-Beltran ◽  
...  

AbstractObjectiveTo ascertain the prevalence of and association between main lifestyle factors (diet, physical activity, alcohol consumption and smoking) in students from the Balearic Islands University.DesignA cross-sectional, descriptive study. A questionnaire including questions on lifestyle, dietary habits and physical activity habits was administered to the students. Four different diet quality scores were calculated (Diet Diversity Score, Mediterranean Diet Score, Dietary Guidelines Score and Global Dietary Guidelines Score).SettingA sample of students from the Balearic Islands University.SubjectsNine hundred and eighty-seven students (45·5 % males; mean age 21·5 (sd 3·3) years).ResultsThe dietary pattern of the student population was characterized by a low consumption of cereals and tubers, fruits, vegetables, olive oil, legumes and nuts, and a high consumption of processed meat, sweets, snacks, soft drinks and pastries. Linear, positive and statistically significant correlations were found between the number of meals consumed daily and all of the diet quality scores determined. Determinants of diet quality, both in the univariate and multivariate analyses, were physical activity practice, sex, age and number of meals consumed daily.ConclusionsRisk factors such as smoking, diet and physical inactivity had a tendency of clustering among Spanish university students. Overall diet quality was low, due to important departures from dietary recommendations and loss of the traditional Mediterranean dietary pattern. Nutritional education campaigns that include promotion of physical activity practice are needed to improve the overall health status of this population.


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